The antiapoptotic gene A1/BFL1 is a WT1 target gene that mediates granulocytic differentiation and resistance to chemotherapy.
about
The Wilms' tumor suppressor protein WT1 is processed by the serine protease HtrA2/OmiA1/Bfl-1 in leukocyte development and cell deathT-cell immune responses to Wilms tumor 1 protein in myelodysplasia responsive to immunosuppressive therapyUp-regulation of anti-apoptotic genes confers resistance to the novel anti-leukaemic compound PEP005 in primary AML cellsCharacterisation and manipulation of docetaxel resistant prostate cancer cell lines.Identification of a Novel C-Terminal Truncated WT1 Isoform with Antagonistic Effects against Major WT1 Isoforms.Wilms' tumor 1 silencing decreases the viability and chemoresistance of glioblastoma cells in vitro: a potential role for IGF-1R de-repressionThe transcription factor Wilms tumor 1 confers resistance in myeloid leukemia cells against the proapoptotic therapeutic agent TRAIL (tumor necrosis factor α-related apoptosis-inducing ligand) by regulating the antiapoptotic protein Bcl-xLNFAT but not NF-kappaB is critical for transcriptional induction of the prosurvival gene A1 after IgE receptor activation in mast cellsMolecular mechanisms of drug resistance in acute myeloid leukaemia.Tumour-associated antigens: considerations for their use in tumour immunotherapy.BCL2A1: the underdog in the BCL2 family.Leukemia-associated antigens and their relevance to the immunotherapy of acute myeloid leukemia.WT1 Alternative Splicing: Role of Its Isoforms in Neuroblastoma.Bcl-2 proteins in development, health, and disease of the hematopoietic system.WT1-mediated repression of the proapoptotic transcription factor ZNF224 is triggered by the BCR-ABL oncogeneRole of WT1-ZNF224 interaction in the expression of apoptosis-regulating genes.WT1 protein directly regulates expression of vascular endothelial growth factor and is a mediator of tumor response to hypoxia.WT1 induction of mitogen-activated protein kinase phosphatase 3 represents a novel mechanism of growth suppression.HtrA2, taming the oncogenic activities of WT1.DNA and RNA binding by the Wilms' tumour gene 1 (WT1) protein +KTS and -KTS isoforms-From initial observations to recent global genomic analyses.Synthetic CpG oligonucleotides induce a genetic profile ameliorating murine myocardial I/R injury.Deregulated expression of A1, Bcl-2, Bcl-xL, and Mcl-1 antiapoptotic proteins and Bid, Bad, and Bax proapoptotic genes in polycythemia vera patients
P2860
Q24655084-99540286-7AC9-4EDC-BE0F-1BCF2BDB8962Q27691571-18A46676-91E4-4188-B359-AD48E70E6960Q34707452-6AB01767-F42B-4740-BD86-9CB636DC6943Q34781362-634D0706-EC34-4B24-B5B4-BC6462096DA5Q35462077-8BC94E8D-5D75-4C11-B974-DE2D1B0F11E1Q35668616-38CEF70D-9BE4-4E55-AC61-4830980298FAQ35751162-82E1D6FB-1A56-495E-802D-EE081BAE861BQ36294675-75E28243-9B0C-48B5-BB61-B88DFD047641Q36491849-CE5D6209-8916-4BCC-A304-6AAC750C9682Q36835812-1A1BDA3E-78DA-48E1-B6A9-D7F0FEDB023EQ37848203-128892F4-8411-4F24-971F-CBAC394CD79BQ37954995-CCB234D3-0DE4-4A57-A8B7-9E9BBE9D3D00Q38015123-4E770B30-B12E-43E2-99D1-C357EA3DCFCFQ38680330-BF5D79A2-6804-4365-8D9E-049628DE742EQ38735628-200142DD-1BFF-44A3-868D-4F47237DC580Q38839647-8CA76211-6DEF-436E-8BBF-701CF4505979Q39202260-016A0556-82FB-4FF8-86DF-0E3599BD0786Q39937224-86F8EB33-7E83-4F21-B747-E280961B1CCDQ39958704-E652CDB2-9153-41BB-8885-FD02583C2E2CQ42061130-F03F3E2C-7FF2-4F32-83DA-CDE515B2AE32Q47294532-93050D0F-2183-4317-85C7-99B2083576D0Q55366238-6CE5E3D2-544A-4D69-B602-9A110E89AA02Q56787010-81613ADA-49B0-41E6-ACF0-E97211A4CC55
P2860
The antiapoptotic gene A1/BFL1 is a WT1 target gene that mediates granulocytic differentiation and resistance to chemotherapy.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
The antiapoptotic gene A1/BFL1 ...... nd resistance to chemotherapy.
@en
The antiapoptotic gene A1/BFL1 ...... nd resistance to chemotherapy.
@nl
type
label
The antiapoptotic gene A1/BFL1 ...... nd resistance to chemotherapy.
@en
The antiapoptotic gene A1/BFL1 ...... nd resistance to chemotherapy.
@nl
prefLabel
The antiapoptotic gene A1/BFL1 ...... nd resistance to chemotherapy.
@en
The antiapoptotic gene A1/BFL1 ...... nd resistance to chemotherapy.
@nl
P2093
P2860
P1433
P1476
The antiapoptotic gene A1/BFL1 ...... nd resistance to chemotherapy.
@en
P2093
Allen R Chen
David M Loeb
Emily A Burwell
Kida A Thompson
Lesley A Simpson
Samira Shahnaz
P2860
P304
P356
10.1182/BLOOD-2005-10-4025
P407
P577
2006-02-16T00:00:00Z