about
Novel self-inactivating vectors for reconstitution of Wiskott-Aldrich syndrome.Modified lentiviral LTRs allow Flp recombinase-mediated cassette exchange and in vivo tracing of "factor-free" induced pluripotent stem cells.Insertional transformation of hematopoietic cells by self-inactivating lentiviral and gammaretroviral vectors.Protein transduction from retroviral Gag precursorsSkin tissue generation by laser cell printing.Avoiding cytotoxicity of transposases by dose-controlled mRNA deliverySustained knockdown of a disease-causing gene in patient-specific induced pluripotent stem cells using lentiviral vector-based gene therapy.Biosafety features of lentiviral vectorsPotent and reversible lentiviral vector restriction in murine induced pluripotent stem cells.Development of novel efficient SIN vectors with improved safety features for Wiskott-Aldrich syndrome stem cell based gene therapy.Rescue of ATP7B function in hepatocyte-like cells from Wilson's disease induced pluripotent stem cells using gene therapy or the chaperone drug curcumin.Limited complementarity between U1 snRNA and a retroviral 5' splice site permits its attenuation via RNA secondary structure.Physiological promoters reduce the genotoxic risk of integrating gene vectors.Murine leukemia virus regulates alternative splicing through sequences upstream of the 5' splice site.New way of regulating alternative splicing in retroviruses: the promoter makes a difference.
P50
Q33419981-E539BF3E-1CFF-4D64-9361-B9C774328D2EQ33587018-9225F6C4-1D80-4122-A163-8A1D287EBBA0Q33713156-0F2B646A-D0F9-48A3-90C8-C6430EE2D4BAQ33842785-AF46F14F-118C-4C95-AFDD-A4786D89BCFDQ34157061-CB3CFF0E-CF85-4002-B77A-9CE6C014DCB5Q35198350-1A128874-F205-4877-B523-4DE84B30C721Q37124547-A1F2F590-5B2D-4E90-8E36-31B9A527997FQ38073294-CDEC3439-6AF2-45AA-9746-85545D224475Q38751544-5B8745C3-375B-47FD-A068-9303A1C5D996Q39488638-0E8B6DAB-1004-4C7D-A286-86D04FEAF8BDQ39748845-98B688DA-1458-47EA-802C-6F449C988E29Q39783741-129E2A3A-C9C1-47E4-9D89-03B611290585Q40003414-E669E89B-A18B-4DB6-839F-A565C3C8DEDDQ40220650-5D41D1DF-707D-406F-A71D-6334344262EBQ41775010-5242A8BF-57EF-43D0-BE67-454E033C6EAB
P50
description
onderzoeker
@nl
name
Daniela Zychlinski
@ast
Daniela Zychlinski
@en
Daniela Zychlinski
@es
Daniela Zychlinski
@nl
Daniela Zychlinski
@sl
type
label
Daniela Zychlinski
@ast
Daniela Zychlinski
@en
Daniela Zychlinski
@es
Daniela Zychlinski
@nl
Daniela Zychlinski
@sl
prefLabel
Daniela Zychlinski
@ast
Daniela Zychlinski
@en
Daniela Zychlinski
@es
Daniela Zychlinski
@nl
Daniela Zychlinski
@sl