HDAC6 Brain Mapping with [18F]Bavarostat Enabled by a Ru-Mediated Deoxyfluorination

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HDAC6 Brain Mapping with [18F]Bavarostat Enabled by a Ru-Mediated Deoxyfluorination

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2017 nî lūn-bûn

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2017年の論文

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2017年論文

@yue

2017年論文

@zh-hant

2017年論文

@zh-hk

2017年論文

@zh-mo

2017年論文

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2017年论文

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2017年论文

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2017年论文

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HDAC6 Brain Mapping with [18F]Bavarostat Enabled by a Ru-Mediated Deoxyfluorination

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HDAC6 Brain Mapping with [18F]Bavarostat Enabled by a Ru-Mediated Deoxyfluorination

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HDAC6 Brain Mapping with [18F]Bavarostat Enabled by a Ru-Mediated Deoxyfluorination

@en

HDAC6 Brain Mapping with [18F]Bavarostat Enabled by a Ru-Mediated Deoxyfluorination

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HDAC6 Brain Mapping with [18F]Bavarostat Enabled by a Ru-Mediated Deoxyfluorination

@en

HDAC6 Brain Mapping with [18F]Bavarostat Enabled by a Ru-Mediated Deoxyfluorination

@nl

P1476

HDAC6 Brain Mapping with [18F]Bavarostat Enabled by a Ru-Mediated Deoxyfluorination

@en

P2093

Arthur J Campbell

http://www.w3.org/2001/XMLSchema#string

Florence F Wagner

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Frederick A Schroeder

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Jacob M Hooker

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Martin G Strebl

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Misha M Riley

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Peter S Chindavong

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Stephen J Haggarty

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Tobias Ritter

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Wen-Ning Zhao

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P2860

Exploration of the HDAC2 foot pocket: Synthesis and SAR of substituted N-(2-aminophenyl)benzamides

Acetylation of non-histone proteins modulates cellular signalling at multiple levels

Extra precision glide: docking and scoring incorporating a model of hydrophobic enclosure for protein-ligand complexes

In vivo imaging of histone deacetylases (HDACs) in the central nervous system and major peripheral organs.

Altered microtubule dynamics and vesicular transport in mouse and human MeCP2-deficient astrocytes.

Differential expression of 12 histone deacetylase (HDAC) genes in astrocytomas and normal brain tissue: class II and IV are hypoexpressed in glioblastomas.

Radionuclide labeling and evaluation of candidate radioligands for PET imaging of histone deacetylase in the brain

Image-guided synthesis reveals potent blood-brain barrier permeable histone deacetylase inhibitors.

Rational design and simple chemistry yield a superior, neuroprotective HDAC6 inhibitor, tubastatin A

Design, synthesis, and evaluation of hydroxamic acid-based molecular probes for in vivo imaging of histone deacetylase (HDAC) in brain.

P304

1006-1014

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P31

scholarly article

P356

10.1021/ACSCENTSCI.7B00274

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Thomas M Morin

P577

2017-09-06T00:00:00Z

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P698

28979942

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P932

5620987

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