about
Engineering and systems-level analysis of Saccharomyces cerevisiae for production of 3-hydroxypropionic acid via malonyl-CoA reductase-dependent pathwayImproving production of malonyl coenzyme A-derived metabolites by abolishing Snf1-dependent regulation of Acc1Diversion of flux toward sesquiterpene production in Saccharomyces cerevisiae by fusion of host and heterologous enzymes.Profiling of cytosolic and peroxisomal acetyl-CoA metabolism in Saccharomyces cerevisiaeBiofuels. Altered sterol composition renders yeast thermotolerant.De novo production of resveratrol from glucose or ethanol by engineered Saccharomyces cerevisiae.Adaptive mutations in sugar metabolism restore growth on glucose in a pyruvate decarboxylase negative yeast strain.Genetic modulation of the overexpression of tailoring genes eryK and eryG leading to the improvement of erythromycin A purity and production in Saccharopolyspora erythraea fermentationThermotolerant yeasts selected by adaptive evolution express heat stress response at 30 °C.Advances in metabolic pathway and strain engineering paving the way for sustainable production of chemical building blocks.From flavors and pharmaceuticals to advanced biofuels: production of isoprenoids in Saccharomyces cerevisiae.Microbial acetyl-CoA metabolism and metabolic engineering.Enabling technologies to advance microbial isoprenoid production.Biobased organic acids production by metabolically engineered microorganisms.Coupled incremental precursor and co-factor supply improves 3-hydroxypropionic acid production in Saccharomyces cerevisiae.Effects of acetoacetyl-CoA synthase expression on production of farnesene in Saccharomyces cerevisiae.Functional expression and evaluation of heterologous phosphoketolases in Saccharomyces cerevisiaeEngineering of acetyl-CoA metabolism for the improved production of polyhydroxybutyrate in Saccharomyces cerevisiaeFunctional pyruvate formate lyase pathway expressed with two different electron donors in Saccharomyces cerevisiae at aerobic growth.Comparison of the metabolic response to over-production of p-coumaric acid in two yeast strains.Elimination of the last reactions in ergosterol biosynthesis alters the resistance of Saccharomyces cerevisiae to multiple stresses.Improving biobutanol production in engineered Saccharomyces cerevisiae by manipulation of acetyl-CoA metabolism.Enhancing the copy number of episomal plasmids in Saccharomyces cerevisiae for improved protein production.Ach1 is involved in shuttling mitochondrial acetyl units for cytosolic C2 provision in Saccharomyces cerevisiae lacking pyruvate decarboxylase.Global rewiring of cellular metabolism renders Saccharomyces cerevisiae Crabtree negativeEstablishing a platform cell factory through engineering of yeast acetyl-CoA metabolismDynamic control of gene expression in Saccharomyces cerevisiae engineered for the production of plant sesquitepene α-santalene in a fed-batch modeModular Pathway Rewiring of Yeast for Amino Acid ProductionLipid engineering combined with systematic metabolic engineering of Saccharomyces cerevisiae for high-yield production of lycopeneProduction of 3-hydroxypropionic acid from glucose and xylose by metabolically engineered Saccharomyces cerevisiaeHeterologous phosphoketolase expression redirects flux towards acetate, perturbs sugar phosphate pools and increases respiratory demand in Saccharomyces cerevisiaeHarnessing xylose pathways for biofuels productionRewiring carbon metabolism in yeast for high level production of aromatic chemicalsMetabolic engineering and transcriptomic analysis of Saccharomyces cerevisiae producing p-coumaric acid from xyloseExpanding the Dynamic Range of a Transcription Factor-Based Biosensor in Saccharomyces cerevisiaeEffects of overexpression of STB5 in Saccharomyces cerevisiae on fatty acid biosynthesis, physiology and transcriptomeAdaptive laboratory evolution of tolerance to dicarboxylic acids in Saccharomyces cerevisiae
P50
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P50
description
onderzoeker
@nl
researcher ORCID: 0000-0002-2146-6008
@en
name
Yun Chen
@ast
Yun Chen
@en
Yun Chen
@es
Yun Chen
@nl
Yun Chen
@sl
type
label
Yun Chen
@ast
Yun Chen
@en
Yun Chen
@es
Yun Chen
@nl
Yun Chen
@sl
prefLabel
Yun Chen
@ast
Yun Chen
@en
Yun Chen
@es
Yun Chen
@nl
Yun Chen
@sl
P1053
G-6645-2017
P106
P1153
55922395800
P21
P31
P3829
P3835
P496
0000-0002-2146-6008