about
Viewing dynamic assembly of molecular complexes by multi-wavelength single-molecule fluorescence.Visualizing the splicing of single pre-mRNA molecules in whole cell extract.Design and construction of a multiwavelength, micromirror total internal reflectance fluorescence microscope.Bacterial RNA polymerase can retain σ70 throughout transcription.Single-molecule colocalization FRET evidence that spliceosome activation precedes stable approach of 5' splice site and branch site.RNA polymerase approaches its promoter without long-range sliding along DNASingle molecule analysis reveals reversible and irreversible steps during spliceosome activationMulti-wavelength single-molecule fluorescence analysis of transcription mechanisms.The dimerization equilibrium of a ClC Cl(-)/H(+) antiporter in lipid bilayers.Single-molecule studies of origin licensing reveal mechanisms ensuring bidirectional helicase loading.Quantifying transient interactions between Bacillus phosphatidylinositol-specific phospholipase-C and phosphatidylcholine-rich vesicles.The covalent trimethoprim chemical tag facilitates single molecule imaging with organic fluorophores.Alternative spliceosome assembly pathways revealed by single-molecule fluorescence microscopyA general mechanism for competitor-induced dissociation of molecular complexes.Mechanism of transcription initiation at an activator-dependent promoter defined by single-molecule observation.Ordered and dynamic assembly of single spliceosomes.Synergistic assembly of human pre-spliceosomes across introns and exons.Detection of ferromagnetic domains in a two-dimensional nuclear-spin systemZero-field magnetic order in the boundary layers of 3He on GrafoilThermal boundary resistance between PrNi5 and liquid 3HeSpatially resolved phase imaging of a programmable liquid-crystal gratingA conserved Mcm4 motif is required for Mcm2-7 double-hexamer formation and origin DNA unwindingHigh-efficiency liquid-crystal optical phased-array beam steeringDelayed inhibition mechanism for secondary channel factor regulation of ribosomal RNA transcription
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Larry J Friedman
@ast
Larry J Friedman
@en
Larry J Friedman
@es
Larry J Friedman
@nl
Larry J Friedman
@sl
type
label
Larry J Friedman
@ast
Larry J Friedman
@en
Larry J Friedman
@es
Larry J Friedman
@nl
Larry J Friedman
@sl
prefLabel
Larry J Friedman
@ast
Larry J Friedman
@en
Larry J Friedman
@es
Larry J Friedman
@nl
Larry J Friedman
@sl
P106
P21
P31
P496
0000-0003-4946-8731