about
The 19-kDa Mycobacterium tuberculosis protein induces macrophage apoptosis through Toll-like receptor-2The p110α and p110β isoforms of class I phosphatidylinositol 3-kinase are involved in toll-like receptor 5 signaling in epithelial cellsGeneration and characterization of murine alternatively activated macrophages.SHIP, SHIP2, and PTEN activities are regulated in vivo by modulation of their protein levels: SHIP is up-regulated in macrophages and mast cells by lipopolysaccharide.The role of SHIP1 in macrophage programming and activation.The inositol phosphatase SHIP controls Salmonella enterica serovar Typhimurium infection in vivoIgE-induced mast cell survival requires the prolonged generation of reactive oxygen species.SHIP prevents lipopolysaccharide from triggering an antiviral response in micePhosphatase regulation of macrophage activation.SHIP represses Th2 skewing by inhibiting IL-4 production from basophils.Salmonella enterica serovar Typhimurium periplasmic superoxide dismutases SodCI and SodCII are required for protection against the phagocyte oxidative burst.Tyrosine phosphorylation of SHIP promotes its proteasomal degradation.Linkage of Meis1 leukemogenic activity to multiple downstream effectors including Trib2 and Ccl3.Monocyte p110alpha phosphatidylinositol 3-kinase regulates phagocytosis, the phagocyte oxidase, and cytokine production.The Flt3 receptor tyrosine kinase collaborates with NUP98-HOX fusions in acute myeloid leukemia.IFN-γ directly inhibits murine B-cell precursor leukemia-initiating cell proliferation early in life.The Crohn's disease-associated polymorphism in ATG16L1 (rs2241880) reduces SHIP gene expression and activity in human subjects.Impaired NLRP3 inflammasome activity during fetal development regulates IL-1β production in human monocytesα-Integrin expression and function modulates presentation of cell surface calreticulin.Depletion and reconstitution of macrophages in mice.1alpha,25-dihydroxyvitamin D(3)-induced myeloid cell differentiation is regulated by a vitamin D receptor-phosphatidylinositol 3-kinase signaling complex.SHIP represses the generation of IL-3-induced M2 macrophages by inhibiting IL-4 production from basophils.Arginase activity in alternatively activated macrophages protects PI3Kp110δ deficient mice from dextran sodium sulfate induced intestinal inflammation.Intravenous immunoglobulin skews macrophages to an anti-inflammatory, IL-10-producing activation state.SHIP regulates the reciprocal development of T regulatory and Th17 cells.Combined immunodeficiency associated with homozygous MALT1 mutations.Derivation and characterization of murine alternatively activated (M2) macrophages.SHIP represses the generation of alternatively activated macrophages.Mutant IDH1 promotes leukemogenesis in vivo and can be specifically targeted in human AML.Assessment of Antibody-based Drugs Effects on Murine Bone Marrow and Peritoneal Macrophage Activation.SHIP negatively regulates type II immune responses in mast cells and macrophages.Endosomal pH modulation by peptide-gold nanoparticle hybrids enables potent anti-inflammatory activity in phagocytic immune cells.Inflammatory Bowel Disease and Immunonutrition: Novel Therapeutic Approaches Through Modulation of Diet and the Gut Microbiome.SHIP-deficient, alternatively activated macrophages protect mice during DSS-induced colitis.Activity of SHIP, Which Prevents Expression of Interleukin 1β, Is Reduced in Patients With Crohn's Disease.Alternative activation of macrophages by IL-4 requires SHIP degradation.Modeling the functional heterogeneity of leukemia stem cells: role of STAT5 in leukemia stem cell self-renewal.CD47-ligation induced cell death in T-acute lymphoblastic leukemia.IVIg and LPS Co-stimulation Induces IL-10 Production by Human Monocytes, Which Is Compromised by an FcγRIIA Disease-Associated Gene VariantA Low Carbohydrate, High Protein Diet Slows Tumor Growth and Prevents Cancer Initiation
P50
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P50
description
hulumtuese
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Laura M Sly
@ast
Laura M Sly
@en
Laura M Sly
@es
Laura M Sly
@nl
Laura M Sly
@sl
type
label
Laura M Sly
@ast
Laura M Sly
@en
Laura M Sly
@es
Laura M Sly
@nl
Laura M Sly
@sl
prefLabel
Laura M Sly
@ast
Laura M Sly
@en
Laura M Sly
@es
Laura M Sly
@nl
Laura M Sly
@sl
P106
P21
P31
P496
0000-0002-1673-467X