Engineering the redox potential over a wide range within a new class of FeS proteins.
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Mutation of the His ligand in mitoNEET stabilizes the 2Fe–2S cluster despite conformational heterogeneity in the ligand environmentStructure and Molecular Evolution of CDGSH Iron-Sulfur DomainsAllosteric control in a metalloprotein dramatically alters function.A point mutation in the [2Fe–2S] cluster binding region of the NAF-1 protein (H114C) dramatically hinders the cluster donor propertiesEnhancing Mn(II)-Binding and Manganese Peroxidase Activity in a Designed Cytochrome c Peroxidase through Fine-Tuning Secondary-Sphere InteractionsConserved hydrogen bonding networks of MitoNEET tune Fe-S cluster binding and structural stability.Interdomain communication revealed in the diabetes drug target mitoNEETFacile transfer of [2Fe-2S] clusters from the diabetes drug target mitoNEET to an apo-acceptor proteinNADPH inhibits [2Fe-2S] cluster protein transfer from diabetes drug target MitoNEET to an apo-acceptor protein.Design of a single protein that spans the entire 2-V range of physiological redox potentialsDesign and fine-tuning redox potentials of metalloproteins involved in electron transfer in bioenergetics.Oxidized and reduced [2Fe-2S] clusters from an iron(I) synthon.Phylogenetic analysis of eukaryotic NEET proteins uncovers a link between a key gene duplication event and the evolution of vertebrates.Electron transfer and proton-coupled electron transfer reactivity and self-exchange of synthetic [2Fe-2S] complexes: models for Rieske and mitoNEET clustersModel of the MitoNEET [2Fe-2S] Cluster Shows Proton Coupled Electron Transfer.Dissection of hydrogen bond interaction network around an iron-sulfur cluster by site-specific isotope labeling of hyperthermophilic archaeal Rieske-type ferredoxin.Molecular Dynamics Simulations of the [2Fe-2S] Cluster-Binding Domain of NEET Proteins Reveal Key Molecular Determinants That Induce Their Cluster Transfer/Release.Characterization of Arabidopsis NEET reveals an ancient role for NEET proteins in iron metabolism.Distinguishing the Protonation State of the Histidine Ligand to the Oxidized Iron-Sulfur Cluster from the MitoNEET Family of Proteins.The unique fold and lability of the [2Fe-2S] clusters of NEET proteins mediate their key functions in health and disease.Photoelectron spectroscopy and density functional theory studies of (FeS)mH- (m = 2-4) cluster anions: effects of the single hydrogen.Extending the essential dynamics analysis to investigate molecular properties: application to the redox potential of proteins.Properties of iron sulfide, hydrosulfide, and mixed sulfide/hydrosulfide cluster anions through photoelectron spectroscopy and density functional theory calculations.Redox tuning of two biological copper centers through non-covalent interactions: same trend but different magnitude
P2860
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P2860
Engineering the redox potential over a wide range within a new class of FeS proteins.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Engineering the redox potential over a wide range within a new class of FeS proteins.
@en
Engineering the redox potential over a wide range within a new class of FeS proteins.
@nl
type
label
Engineering the redox potential over a wide range within a new class of FeS proteins.
@en
Engineering the redox potential over a wide range within a new class of FeS proteins.
@nl
prefLabel
Engineering the redox potential over a wide range within a new class of FeS proteins.
@en
Engineering the redox potential over a wide range within a new class of FeS proteins.
@nl
P2093
P2860
P356
P1476
Engineering the redox potential over a wide range within a new class of FeS proteins.
@en
P2093
Andrea R Conlan
Danny A Halim
Edward C Abresch
John A Zuris
Mark L Paddock
Patricia A Jennings
P2860
P304
13120-13122
P356
10.1021/JA103920K
P407
P577
2010-09-01T00:00:00Z