Impaired thermogenesis and adipose tissue development in mice with fat-specific disruption of insulin and IGF-1 signalling. - Test2 - elhamkhani - TriplyDB

Impaired thermogenesis and adipose tissue development in mice with fat-specific disruption of insulin and IGF-1 signalling.

Impaired thermogenesis and adipose tissue development in mice with fat-specific disruption of insulin and IGF-1 signalling.

http://www.wikidata.org/entity/Q42427528

about

Browning of white adipose tissue uncouples glucose uptake from insulin signaling Transcription regulator TRIP-Br2 mediates ER stress-induced brown adipocytes dysfunction Vascular calcifying progenitor cells possess bidirectional differentiation potentials The obesity-induced transcriptional regulator TRIP-Br2 mediates visceral fat endoplasmic reticulum stress-induced inflammation DJ-1 contributes to adipogenesis and obesity-induced inflammation.Adipocytes arise from multiple lineages that are heterogeneously and dynamically distributed.Altered miRNA processing disrupts brown/white adipocyte determination and associates with lipodystrophy.Adaptive thermogenesis in adipocytes: is beige the new brown?Adipose tissue insulin receptor knockdown via a new primate-derived hybrid recombinant AAV serotype.Thyrotropin and obesity: increased adipose triglyceride content through glycerol-3-phosphate acyltransferase 3.Fatty acid binding protein 4 and 5 play a crucial role in thermogenesis under the conditions of fasting and cold stress Brown fat determination and development from muscle precursor cells by novel action of bone morphogenetic protein 6 ASC-1, PAT2, and P2RX5 are cell surface markers for white, beige, and brown adipocytes.Altered metabolism and resistance to obesity in long-lived mice producing reduced levels of IGF-I Disruption of insulin signaling in Myf5-expressing progenitors leads to marked paucity of brown fat but normal muscle development Differential Role of Insulin/IGF-1 Receptor Signaling in Muscle Growth and Glucose Homeostasis Suppression of hyperinsulinaemia in growing female mice provides long-term protection against obesity.Altered liver expression of genes involved in lipid and glucose metabolism in mice with partial IGF-1 deficiency: an experimental approach to metabolic syndrome The Rho-guanine nucleotide exchange factor PDZ-RhoGEF governs susceptibility to diet-induced obesity and type 2 diabetes.Lessons on conditional gene targeting in mouse adipose tissue IGFBP-2 is a negative predictor of cold-induced brown fat and bone mineral density in young non-obese women Dynamic gene expression profiles during postnatal development of porcine subcutaneous adipose.Insulin signalling mechanisms for triacylglycerol storage.Lack of AKT in adipocytes causes severe lipodystrophy.Olive leaf extract attenuates obesity in high-fat diet-fed mice by modulating the expression of molecules involved in adipogenesis and thermogenesis.Altered somatotroph feedback regulation improves metabolic efficiency and limits adipose deposition in male mice.Linking maternal obesity to early insulin resistance.Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression.Pharmacologic agents for type 2 diabetes therapy and regulation of adipogenesis.MicroRNAs in dysfunctional adipose tissue: cardiovascular implications.Interorgan Communication Pathways in Physiology: Focus on Drosophila.Macrophage and adipocyte IGF1 maintain adipose tissue homeostasis during metabolic stresses Peroxisome proliferator-activated receptor γ regulates genes involved in insulin/insulin-like growth factor signaling and lipid metabolism during adipogenesis through functionally distinct enhancer classes.Characteristics of adipose tissue macrophages and macrophage-derived insulin-like growth factor-1 in virus-induced obesity.Metabolic recovery of lipodystrophy, liver steatosis, and pancreatic β cell proliferation after the withdrawal of OSI-906.Muscle Conditional Medium Reduces Intramuscular Adipocyte Differentiation and Lipid Accumulation through Regulating Insulin Signaling Lipodystrophy Due to Adipose Tissue-Specific Insulin Receptor Knockout Results in Progressive NAFLD.Differential organ phenotypes after postnatal Igf1r gene conditional deletion induced by tamoxifen in UBC-CreERT2; Igf1r fl/fl double transgenic mice.Differential Roles of Insulin and IGF-1 Receptors in Adipose Tissue Development and Function IGFBP4 Is Required for Adipogenesis and Influences the Distribution of Adipose Depots.

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Impaired thermogenesis and adipose tissue development in mice with fat-specific disruption of insulin and IGF-1 signalling.

http://www.wikidata.org/entity/Q42427528

description

2012 nî lūn-bûn

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2012年论文

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2012年论文

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name

Impaired thermogenesis and adi ...... insulin and IGF-1 signalling.

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Impaired thermogenesis and adi ...... insulin and IGF-1 signalling.

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type

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Impaired thermogenesis and adi ...... insulin and IGF-1 signalling.

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Impaired thermogenesis and adi ...... insulin and IGF-1 signalling.

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Impaired thermogenesis and adi ...... insulin and IGF-1 signalling.

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Impaired thermogenesis and adi ...... insulin and IGF-1 signalling.

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Nature Communications

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Impaired thermogenesis and adi ...... insulin and IGF-1 signalling.

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Chong Wee Liew

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Graham Smyth

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Jeremie Boucher

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Kevin Y Lee

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Marcelo A Mori

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Matthias Bluher

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Michael Rourk

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Steven J Russell

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Yazmin Macotela

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Identification and importance of brown adipose tissue in adult humans

New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure

Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver

Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins

Brown adipose tissue-specific insulin receptor knockout shows diabetic phenotype without insulin resistance

Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese

UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality

Cold-activated brown adipose tissue in healthy men

Functional brown adipose tissue in healthy adults

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10.1038/NCOMMS1905

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