MDM2 overexpression generates a skin phenotype in both wild type and p53 null mice.
about
A mitosis block links active cell cycle with human epidermal differentiation and results in endoreplication.MDM2 induces hyperplasia and premalignant lesions when expressed in the basal layer of the epidermis.A small nuclear RNA, hdm365, is the major processing product of the human mdm2 gene.A novel microdeletion in LOR causing autosomal dominant loricrin keratoderma.The RING finger domain of MDM2 is essential for MDM2-mediated TGF-beta resistance.In Vitro Differentiation Potential of Human Placenta Derived Cells into Skin Cells.The mysterious human epidermal cell cycle, or an oncogene-induced differentiation checkpoint.A functional SNP in the MDM2 promoter, pigmentary phenotypes, and risk of skin cancerCellular stress response pathway system as a sentinel ensemble in toxicological screening.MDM2 and CDK4 amplifications are rare events in salivary duct carcinomasMolecular pathways: targeting Mdm2 and Mdm4 in cancer therapy.Cycling up the epidermis: reconciling 100 years of debate.A novel regulation of VEGF expression by HIF-1α and STAT3 in HDM2 transfected prostate cancer cells.The mdm2 proto-oncogene sensitizes human medullary thyroid carcinoma cells to ionizing radiation.Relationship between the epithelial expression of hMLH1, MDM2, and p63 and lower lip carcinogenesis.Switch from p53 to MDM2 as differentiating human keratinocytes lose their proliferative potential and increase in cellular size.Overexpression of mouse Mdm2 induces developmental phenotypes in Drosophila.Frequent alteration of MDM2 and p53 in the molecular progression of recurring non-Hodgkin's lymphoma.
P2860
Q33781053-D2CFD67B-E9DE-4370-AF92-A9FB24D15FA8Q34489720-FC926044-7FC6-488D-9F0A-156D6D1CC4C4Q34770842-D576AC1D-DE18-4BD8-B986-C7DE22E110CDQ35004400-F6C5E730-95AC-40B4-8766-0DB1FE30D87AQ35810677-33C41147-5309-4880-B525-34AB268164E8Q35852403-115E31D6-7C71-4F96-B89E-073271E19B5FQ36581649-EF8E9F4B-6377-4446-B676-2382D1FAED00Q37074563-E7C19E1C-5ACB-4516-9D36-2402702678F6Q37536673-D9F5D3D6-6737-449F-A6DA-8A452DF20454Q37688930-AA625B8E-0158-4341-86F2-CD50D54D0B32Q38069375-87D82DD3-AC7C-43C5-B065-AA882D92037EQ38164815-7A6C85E0-EC23-401E-9B31-DC55DF69E67BQ39457038-7062F753-8923-448E-AB7E-3FA519BD0535Q40738795-E7049912-0B7A-4FB1-8B80-A96362154EB3Q44992018-8D1FDDB3-6E29-4DD5-B24A-EF79DA4980A1Q47231411-239602AA-B827-461A-8B14-3A5E8DD6D909Q52121428-970CB520-8720-425D-960B-9323FDD1DA59Q53721170-87EC9344-B7C4-459B-9481-7DD2AC59D246
P2860
MDM2 overexpression generates a skin phenotype in both wild type and p53 null mice.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
MDM2 overexpression generates a skin phenotype in both wild type and p53 null mice.
@en
MDM2 overexpression generates a skin phenotype in both wild type and p53 null mice.
@nl
type
label
MDM2 overexpression generates a skin phenotype in both wild type and p53 null mice.
@en
MDM2 overexpression generates a skin phenotype in both wild type and p53 null mice.
@nl
prefLabel
MDM2 overexpression generates a skin phenotype in both wild type and p53 null mice.
@en
MDM2 overexpression generates a skin phenotype in both wild type and p53 null mice.
@nl
P2093
P2860
P356
P1433
P1476
MDM2 overexpression generates a skin phenotype in both wild type and p53 null mice
@en
P2093
M Alkhalaf
N Messaddeq
P2860
P2888
P304
P356
10.1038/SJ.ONC.1202448
P407
P577
1999-02-01T00:00:00Z
P5875
P6179
1045798606