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Influence of formulation factors on PpIX production and photodynamic action of novel ALA-loaded microparticles.Processing difficulties and instability of carbohydrate microneedle arrays.Hydrogel-forming and dissolving microneedles for enhanced delivery of photosensitizers and precursors.Antifungal photodynamic therapy.Drug delivery systems for photodynamic therapy.State of the art in benefit-risk analysis: medicines.Protein deregulation associated with breast cancer metastasis.Antibody targeting of camptothecin-loaded PLGA nanoparticles to tumor cells.Preparation and in vivo evaluation of insulin-loaded biodegradable nanoparticles prepared from diblock copolymers of PLGA and PEG.In vitro phototoxicity of 5-aminolevulinic acid and its methyl ester and the influence of barrier properties on their release from a bioadhesive patch.Phototoxicity of 5-aminolevulinic acid in the HeLa cell line as an indicative measure of photodynamic effect after topical administration to gynecological lesions of intraepithelial form.Evaluation of the penetration of 5-aminolevulinic acid through basal cell carcinoma: a pilot study.Hexyl aminolaevulinate is a more effective topical photosensitiser precursor than methyl aminolaevulinate and 5-aminolaevulinic acids when applied in equimolar doses.Novel patch-based systems for the localised delivery of ALA-esters.Influence of penetration enhancers on topical delivery of 5-aminolevulinic acid from bioadhesive patches.Influence of solution viscosity and injection protocol on distribution patterns of jet injectors: application to photodynamic tumour targeting.Aminolevulinic acid-loaded Witepsol microparticles manufactured using a spray congealing procedure: implications for topical photodynamic therapy.Delivery of Methylene Blue and meso-tetra (N-methyl-4-pyridyl) porphine tetra tosylate from cross-linked poly(vinyl alcohol) hydrogels: a potential means of photodynamic therapy of infected wounds.Preliminary clinical assessment of polyvinyl alcohol-tetrahydroxyborate hydrogels as potential topical formulations for local anesthesia of lacerations.Successful photodynamic therapy of vulval Paget's disease using a novel patch-based delivery system containing 5-aminolevulinic acid.Analysis of pyrazine 2,5-dipropionic acid in 5-aminolevulinic acid-loaded urological and topical delivery vehicles: methodology and assay validation.Fast-drying multi-laminate bioadhesive films for transdermal and topical drug delivery.Clinical and immunohistochemical assessment of vulval intraepithelial neoplasia following photodynamic therapy using a novel bioadhesive patch-type system loaded with 5-aminolevulinic acid.Bioadhesive patch-based delivery of 5-aminolevulinic acid to the nail for photodynamic therapy of onychomycosis.Evaluation of a water-soluble bioadhesive patch for photodynamic therapy of vulval lesions.Microneedle arrays permit enhanced intradermal delivery of a preformed photosensitizer.Aminolaevulinic acid diffusion characteristics in 'in vitro' normal human skin and actinic keratosis: implications for topical photodynamic therapy.Microneedle-mediated intradermal delivery of 5-aminolevulinic acid: potential for enhanced topical photodynamic therapy.Stability of 5-aminolevulinic acid in novel non-aqueous gel and patch-type systems intended for topical application.Comparison of a novel spray congealing procedure with emulsion-based methods for the micro-encapsulation of water-soluble drugs in low melting point triglycerides.Effect of poly(ethylene glycol) content and formulation parameters on particulate properties and intraperitoneal delivery of insulin from PLGA nanoparticles prepared using the double-emulsion evaporation procedure.Modulation of gel formation and drug-release characteristics of lidocaine-loaded poly(vinyl alcohol)-tetraborate hydrogel systems using scavenger polyol sugars.Pharmaceutical analysis of 5-aminolevulinic acid in solution and in tissues.Enhanced surface attachment of protein-type targeting ligands to poly(lactide-co-glycolide) nanoparticles using variable expression of polymeric acid functionality.Design and physicochemical characterisation of a bioadhesive patch for dose-controlled topical delivery of imiquimod.Design and evaluation of a water-soluble bioadhesive patch formulation for cutaneous delivery of 5-aminolevulinic acid to superficial neoplastic lesions.Topical bioadhesive patch systems enhance selectivity of protoporphyrin IX accumulation.Modulation of surface charge, particle size and morphological properties of chitosan-TPP nanoparticles intended for gene delivery.Characterisation and in vitro stability of low-dose, lidocaine-loaded poly(vinyl alcohol)-tetrahydroxyborate hydrogels.A non-inferiority randomized controlled trial comparing the clinical effectiveness of anesthesia obtained by application of a novel topical anesthetic putty with the infiltration of lidocaine for the treatment of lacerations in the emergency departm
P50
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hulumtues
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Paul A. McCarron
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Paul A. McCarron
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Paul A. McCarron
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Paul A. McCarron
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Paul A. McCarron
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Paul A. McCarron
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Paul A. McCarron
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Paul A. McCarron
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Paul A. McCarron
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Paul A. McCarron
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Paul A. McCarron
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Paul A. McCarron
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Paul A. McCarron
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Paul A. McCarron
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Paul A. McCarron
@sl
P106
P1153
7004926260
P21
P31
P496
0000-0002-2292-9887