The autism-linked UBE3A T485A mutant E3 ubiquitin ligase activates the Wnt/β-catenin pathway by inhibiting the proteasome.
about
Neuronal overexpression of Ube3a isoform 2 causes behavioral impairments and neuroanatomical pathology relevant to 15q11.2-q13.3 duplication syndrome.APC sets the Wnt tone necessary for cerebral cortical progenitor development.Neuronal Proteomic Analysis of the Ubiquitinated Substrates of the Disease-Linked E3 Ligases Parkin and Ube3a.
P2860
The autism-linked UBE3A T485A mutant E3 ubiquitin ligase activates the Wnt/β-catenin pathway by inhibiting the proteasome.
description
2017 nî lūn-bûn
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2017年の論文
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2017年学术文章
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name
The autism-linked UBE3A T485A ...... by inhibiting the proteasome.
@en
The autism-linked UBE3A T485A ...... by inhibiting the proteasome.
@nl
type
label
The autism-linked UBE3A T485A ...... by inhibiting the proteasome.
@en
The autism-linked UBE3A T485A ...... by inhibiting the proteasome.
@nl
prefLabel
The autism-linked UBE3A T485A ...... by inhibiting the proteasome.
@en
The autism-linked UBE3A T485A ...... by inhibiting the proteasome.
@nl
P2093
P2860
P356
P1476
The autism-linked UBE3A T485A ...... by inhibiting the proteasome.
@en
P2093
Giulia Fragola
Jason J Yi
Justin M Wolter
Mark J Zylka
Matthew P Walker
Michael B Major
Michael J Emanuele
Rajarshi Choudhury
Smita R Paranjape
P2860
P304
12503-12515
P356
10.1074/JBC.M117.788448
P407
P577
2017-05-30T00:00:00Z