Critical role of serum response factor in pulmonary myofibroblast differentiation induced by TGF-beta. - Test2 - elhamkhani - TriplyDB

Critical role of serum response factor in pulmonary myofibroblast differentiation induced by TGF-beta.

Critical role of serum response factor in pulmonary myofibroblast differentiation induced by TGF-beta.

http://www.wikidata.org/entity/Q42553529

about

Recent developments in myofibroblast biology: paradigms for connective tissue remodeling Actin cytoskeleton in myofibroblast differentiation: ultrastructure defining form and driving function Key Fibrogenic Signaling The Rho kinases: critical mediators of multiple profibrotic processes and rational targets for new therapies for pulmonary fibrosis A new antifibrotic target of Ac-SDKP: inhibition of myofibroblast differentiation in rat lung with silicosis Motile cilia harbor serum response factor as a mechanism of environment sensing and injury response in the airway Downregulation of TGF-β Receptor-2 Expression and Signaling through Inhibition of Na/K-ATPase Targeting the myofibroblast genetic switch: inhibitors of myocardin-related transcription factor/serum response factor-regulated gene transcription prevent fibrosis in a murine model of skin injury.Local delivery of novel MRTF/SRF inhibitors prevents scar tissue formation in a preclinical model of fibrosis.Genome-wide DNA methylation analysis in lung fibroblasts co-cultured with silica-exposed alveolar macrophages.Prostaglandin E2 inhibits α-smooth muscle actin transcription during myofibroblast differentiation via distinct mechanisms of modulation of serum response factor and myocardin-related transcription factor-A Cellular mechanisms of tissue fibrosis. 8. Current and future drug targets in fibrosis: focus on Rho GTPase-regulated gene transcription.Interferon-gamma-mediated inhibition of serum response factor-dependent smooth muscle-specific gene expression The Purα/Purβ single-strand DNA-binding proteins attenuate smooth-muscle actin gene transactivation in myofibroblasts.Reduced serum content and increased matrix stiffness promote the cardiac myofibroblast transition in 3D collagen matrices Bone marrow-derived cells may not be the original cells for carcinogen-induced mouse gastrointestinal carcinomas Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis Myofibroblasts exhibit enhanced fibronectin assembly that is intrinsic to their contractile phenotype.Serum response factor accelerates the high glucose-induced Epithelial-to-Mesenchymal Transition (EMT) via snail signaling in human peritoneal mesothelial cells.Megakaryoblastic leukemia-1 is required for the development of bleomycin-induced pulmonary fibrosis Delayed stress fiber formation mediates pulmonary myofibroblast differentiation in response to TGF-β.Transforming growth factor-β1-induced transcript 1 protein, a novel marker for smooth muscle contractile phenotype, is regulated by serum response factor/myocardin protein cAMP and Epac in the regulation of tissue fibrosis.Endogenous Semaphorin-7A Impedes Human Lung Fibroblast Differentiation A TRPC6-dependent pathway for myofibroblast transdifferentiation and wound healing in vivo.MBNL1-mediated regulation of differentiation RNAs promotes myofibroblast transformation and the fibrotic response.Transcriptional control of cardiac fibroblast plasticity.Matrix-driven Myosin II Mediates the Pro-fibrotic Fibroblast Phenotype Control of myofibroblast differentiation by microtubule dynamics through a regulated localization of mDia2 Regulation of myofibroblast differentiation by cardiac glycosides Regulation of myofibroblast differentiation and bleomycin-induced pulmonary fibrosis by adrenomedullin.Novel Rho/MRTF/SRF inhibitors block matrix-stiffness and TGF-β-induced fibrogenesis in human colonic myofibroblasts Akt1 mediates α-smooth muscle actin expression and myofibroblast differentiation via myocardin and serum response factor.Antifibrotic effects of noscapine through activation of prostaglandin E2 receptors and protein kinase A.The actin-MRTF-SRF gene regulatory axis and myofibroblast differentiation.Dynamic Interplay of Smooth Muscle α-Actin Gene-Regulatory Proteins Reflects the Biological Complexity of Myofibroblast Differentiation.Smooth Muscle Cell Differentiation: Model Systems, Regulatory Mechanisms, and Vascular Diseases.A differential network analysis approach for lineage specifier prediction in stem cell subpopulations.Pharmacological Inhibition of Myocardin-related Transcription Factor Pathway Blocks Lung Metastases of RhoC-Overexpressing Melanoma.Molecular networks underlying myofibroblast fate and fibrosis.

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P2860

Critical role of serum response factor in pulmonary myofibroblast differentiation induced by TGF-beta.

http://www.wikidata.org/entity/Q42553529

description

2009 nî lūn-bûn

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2009年の論文

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2009年論文

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2009年论文

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2009年论文

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2009年论文

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name

Critical role of serum respons ...... entiation induced by TGF-beta.

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Critical role of serum respons ...... entiation induced by TGF-beta.

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type

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Critical role of serum respons ...... entiation induced by TGF-beta.

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Critical role of serum respons ...... entiation induced by TGF-beta.

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Critical role of serum respons ...... entiation induced by TGF-beta.

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Critical role of serum respons ...... entiation induced by TGF-beta.

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RCMB.2008-0288OC

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American Journal of Respiratory Cell and Molecular Biology

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Critical role of serum respons ...... entiation induced by TGF-beta.

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Nathan Sandbo

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Nickolai O Dulin

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Sangeeta Bhorade

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Steven Kregel

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P2860

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

Signal-regulated activation of serum response factor is mediated by changes in actin dynamics

Serum response factor and myocardin mediate arterial hypercontractility and cerebral blood flow dysregulation in Alzheimer's phenotype.

Human and Drosophila homeodomain proteins that enhance the DNA-binding activity of serum response factor

The myofibroblast: one function, multiple origins

Phosphorylation of the vasodilator-stimulated phosphoprotein regulates its interaction with actin

Prostanoids and prostanoid receptors in signal transduction

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

cAMP- and cGMP-dependent protein kinase phosphorylation sites of the focal adhesion vasodilator-stimulated phosphoprotein (VASP) in vitro and in intact human platelets

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

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332-338

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3

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41

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Sebastien Taurin

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19151320

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2742753

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