Competition between homodimerization and cholesterol binding to the C99 domain of the amyloid precursor protein.
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Regulation of KCNQ/Kv7 family voltage-gated K+ channels by lipids.Probing Structural Dynamics and Topology of the KCNE1 Membrane Protein in Lipid Bilayers via Site-Directed Spin Labeling and Electron Paramagnetic Resonance Spectroscopy.Metals and cholesterol: two sides of the same coin in Alzheimer's disease pathology.EmrE dimerization depends on membrane environment.Structural heterogeneity in transmembrane amyloid precursor protein homodimer is a consequence of environmental selection.Structural investigation of the transmembrane domain of KCNE1 in proteoliposomesIndependent relationship between amyloid precursor protein (APP) dimerization and γ-secretase processivity.Analysis by a highly sensitive split luciferase assay of the regions involved in APP dimerization and its impact on processing.Extension of a protein docking algorithm to membranes and applications to amyloid precursor protein dimerization.Topologically Diverse Human Membrane Proteins Partition to Liquid-Disordered Domains in Phase-Separated Lipid Vesicles.Impact of membrane lipid composition on the structure and stability of the transmembrane domain of amyloid precursor protein.Conformational changes induced by the A21G Flemish mutation in the amyloid precursor protein lead to increased Aβ production.Cholesterol as a co-solvent and a ligand for membrane proteins.Lipid rafts in neurodegeneration and neuroprotection.Impact of bilayer lipid composition on the structure and topology of the transmembrane amyloid precursor C99 proteinStructural and biochemical differences between the Notch and the amyloid precursor protein transmembrane domains.How amyloid precursor protein protects itself from cleavage.Probing the interaction of the potassium channel modulating KCNE1 in lipid bilayers via solid-state NMR spectroscopy.GXXXG-Mediated Parallel and Antiparallel Dimerization of Transmembrane Helices and Its Inhibition by Cholesterol: Single-Pair FRET and 2D IR Studies.Dimerization of the transmembrane domain of amyloid precursor protein is determined by residues around the γ-secretase cleavage sites.Specific Binding of Cholesterol to C99 Domain of Amyloid Precursor Protein Depends Critically on Charge State of Protein.Transthyretin Suppresses Amyloid-β Secretion by Interfering with Processing of the Amyloid-β Protein PrecursorInteraction of the amyloid β peptide with sodium dodecyl sulfate as a membrane-mimicking detergent.Backbone Hydrogen Bond Strengths Can Vary Widely in Transmembrane Helices.Critical size dependence of domain formation observed in coarse-grained simulations of bilayers composed of ternary lipid mixtures.Both positional and chemical variables control in vitro proteolytic cleavage of a presenilin ortholog.The dynamic binding of cholesterol to the multiple sites of C99: as revealed by coarse-grained and all-atom simulations.Mapping Lipid Bilayer Recognition Sites of Metalloproteinases and Other Prospective Peripheral Membrane Proteins.Selective amine labeling of cell surface proteins guided by coiled-coil assembly.Binding of Bexarotene to the Amyloid Precursor Protein Transmembrane Domain in Liposomes Alters its α-Helical Conformation but Inhibits γ-Secretase Non-Selectively.Site-Directed Spin Labeling EPR for Studying Membrane Proteins.Minimotifs dysfunction is pervasive in neurodegenerative disorders
P2860
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P2860
Competition between homodimerization and cholesterol binding to the C99 domain of the amyloid precursor protein.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Competition between homodimeri ...... the amyloid precursor protein.
@en
Competition between homodimeri ...... the amyloid precursor protein.
@nl
type
label
Competition between homodimeri ...... the amyloid precursor protein.
@en
Competition between homodimeri ...... the amyloid precursor protein.
@nl
prefLabel
Competition between homodimeri ...... the amyloid precursor protein.
@en
Competition between homodimeri ...... the amyloid precursor protein.
@nl
P2093
P2860
P356
P1433
P1476
Competition between homodimeri ...... the amyloid precursor protein.
@en
P2093
Charles R Sanders
Eric J Hustedt
Suzanne Brandon
Yuanli Song
P2860
P304
P356
10.1021/BI400735X
P407
P577
2013-07-18T00:00:00Z