Plasmodium falciparum PfA-M1 aminopeptidase is trafficked via the parasitophorous vacuole and marginally delivered to the food vacuole
about
Bestatin-based chemical biology strategy reveals distinct roles for malaria M1- and M17-family aminopeptidasesA Naturally Variable Residue in the S1 Subsite of M1 Family Aminopeptidases Modulates Catalytic Properties and Promotes Functional SpecializationDistribution and biochemical properties of an M1-family aminopeptidase in Plasmodium falciparum indicate a role in vacuolar hemoglobin catabolismAminopeptidase N1 (EtAPN1), an M1 metalloprotease of the apicomplexan parasite Eimeria tenella, participates in parasite development.Fingerprinting the substrate specificity of M1 and M17 aminopeptidases of human malaria, Plasmodium falciparum.Engagement of the S1, S1' and S2' subsites drives efficient catalysis of peptide bond hydrolysis by the M1-family aminopeptidase from Plasmodium falciparum.Proteases as regulators of pathogenesis: examples from the Apicomplexa.Biochemical characterization of aminopeptidase N2 from Toxoplasma gondii.Selective inhibition of PfA-M1, over PfA-M17, by an amino-benzosuberone derivative blocks malaria parasites development in vitro and in vivo.Sitagliptin does not inhibit the M1 alanyl aminopeptidase from Plasmodium falciparum.Multi-targeted activity of maslinic acid as an antimalarial natural compound.Two cap residues in the S1 subsite of a Plasmodium falciparum M1-family aminopeptidase promote broad specificity and enhance catalysis.Metallopeptidases of Toxoplasma gondii: in silico identification and gene expression.
P2860
Q27671783-11975ECC-D405-4527-AC99-E4B590249E30Q27679264-C9D7681C-A649-4F10-AAA2-6D7895AD4B77Q27973831-185B1F24-DE37-4098-8D0C-819B8AE125A8Q34057071-ADA19D1E-239B-46C3-B0FB-7F5F129B492AQ34168471-4455EF0E-1424-4115-8739-C426BF66D304Q35840252-67B9AE86-715D-4645-8E62-78C0A7574409Q37891227-EC7C5442-33AA-47BB-96B6-6F69FBB917CDQ41538728-5EDE38EF-AA41-47C2-BB9D-0EBDE40C647AQ41693109-2AFD6FC6-3E89-4C4A-8977-56ABBBE8B5A7Q42535934-7B50AA2F-B550-45CF-907B-D271654024E1Q42732002-9053E418-A7B5-4DD8-927E-F998A4014701Q45065398-D629D2CC-096F-449F-815B-6C823ECD7372Q55283527-559DB149-85C0-4D27-8088-EA471FDF1478
P2860
Plasmodium falciparum PfA-M1 aminopeptidase is trafficked via the parasitophorous vacuole and marginally delivered to the food vacuole
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Plasmodium falciparum PfA-M1 a ...... delivered to the food vacuole
@en
Plasmodium falciparum PfA-M1 a ...... delivered to the food vacuole
@nl
type
label
Plasmodium falciparum PfA-M1 a ...... delivered to the food vacuole
@en
Plasmodium falciparum PfA-M1 a ...... delivered to the food vacuole
@nl
prefLabel
Plasmodium falciparum PfA-M1 a ...... delivered to the food vacuole
@en
Plasmodium falciparum PfA-M1 a ...... delivered to the food vacuole
@nl
P2093
P2860
P356
P1433
P1476
Plasmodium falciparum PfA-M1 a ...... delivered to the food vacuole
@en
P2093
Julius Nyalwidhe
P2860
P2888
P356
10.1186/1475-2875-9-189
P577
2010-06-30T00:00:00Z
P5875
P6179
1039111973