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Gene-environment interaction in the onset of eczema in infancy: filaggrin loss-of-function mutations enhanced by neonatal cat exposureGeneration Scotland: the Scottish Family Health Study; a new resource for researching genes and heritabilityCharacterization of a cDNA encoding a human kidney, cytochrome P-450 4A fatty acid omega-hydroxylase and the cognate enzyme expressed in Escherichia coliTwelve type 2 diabetes susceptibility loci identified through large-scale association analysisGenetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosisMale preponderance in early diagnosed type 2 diabetes is associated with the ARE insertion/deletion polymorphism in the PPP1R3A locusHaplotype analysis of the PPARgamma Pro12Ala and C1431T variants reveals opposing associations with body weight.The peroxisome proliferator activated receptor delta is required for the differentiation of THP-1 monocytic cells by phorbol esterAssociation of common variation in the PPARA gene with incident myocardial infarction in individuals with type 2 diabetes: a Go-DARTS studyPhenotype standardization for statin-induced myotoxicitySLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and goutEnergy balance and food intake: the role of PPARgamma gene polymorphismsLoss-of-function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizationsA comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery diseaseNew genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes riskThe burden of disease associated with filaggrin mutations: a population-based, longitudinal birth cohort studyA polymorphism controlling ORMDL3 expression is associated with asthma that is poorly controlled by current medicationsUnique mutations in the filaggrin gene in Japanese patients with ichthyosis vulgaris and atopic dermatitisGenome-wide association analysis identifies 13 new risk loci for schizophreniaCommon loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitisFilaggrin null mutations are associated with increased asthma severity in children and young adultsSkin-targeted inhibition of PPAR β/δ by selective antagonists to treat PPAR β/δ-mediated psoriasis-like skin disease in vivoTmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjectsQuantification of cytochrome P450 reductase gene expression in human tissuesDirectional dominance on stature and cognition in diverse human populationsCommon variants associated with plasma triglycerides and risk for coronary artery diseaseDiscovery and refinement of loci associated with lipid levels.A genome-wide association search for type 2 diabetes genes in African AmericansA role for coding functional variants in HNF4A in type 2 diabetes susceptibilityGenome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibilityInteraction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility.Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke.Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.Meta-analysis of genome-wide association studies of HDL cholesterol response to statins.Loss-of-function mutations in APOC3, triglycerides, and coronary diseaseCohort profile: the Scottish Research register SHARE. A register of people interested in research participation linked to NHS data sets.Carrier status for the common R501X and 2282del4 filaggrin mutations is not associated with hearing phenotypes in 5,377 children from the ALSPAC cohort.Ligand modulated antagonism of PPARgamma by genomic and non-genomic actions of PPARdelta.Genetic Variation in Kruppel like Factor 15 Is Associated with Left Ventricular Hypertrophy in Patients with Type 2 Diabetes: Discovery and Replication Cohorts.Variants in Pharmacokinetic Transporters and Glycemic Response to Metformin: A Metgen Meta-Analysis.
P50
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P50
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hulumtues
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հետազոտող
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Colin Palmer
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Colin Palmer
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Colin Palmer
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Colin Palmer
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Colin Palmer
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كولن بالمر
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Colin Palmer
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Colin Palmer
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Colin Palmer
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Colin Palmer
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كولن بالمر
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P1053
C-7053-2008
P106
P1153
57205269772
7403082031
P21
P31
P3829
P496
0000-0002-6415-6560