about
The zinc finger protein ZNF268 is overexpressed in human cervical cancer and contributes to tumorigenesis via enhancing NF-κB signalingNovel activity of KRAB domain that functions to reinforce nuclear localization of KRAB-containing zinc finger proteins by interacting with KAP1FOG-1-mediated recruitment of NuRD is required for cell lineage re-enforcement during haematopoiesisOncostatin M receptor β deficiency attenuates atherogenesis by inhibiting JAK2/STAT3 signaling in macrophages.AKT is a therapeutic target in myeloproliferative neoplasmsPSTPIP2 dysregulation contributes to aberrant terminal differentiation in GATA-1-deficient megakaryocytes by activating LYNIdentification of regulators of polyploidization presents therapeutic targets for treatment of AMKLFLIP: a novel regulator of macrophage differentiation and granulocyte homeostasisCharacterization of microRNA expression profiles and the discovery of novel microRNAs involved in cancer during human embryonic development.Global expression profiling reveals genetic programs underlying the developmental divergence between mouse and human embryogenesis.hERG potassium channel blockage by scorpion toxin BmKKx2 enhances erythroid differentiation of human leukemia cells K562miR-638 regulates differentiation and proliferation in leukemic cells by targeting cyclin-dependent kinase 2Zinc fingers function cooperatively with KRAB domain for nuclear localization of KRAB-containing zinc finger proteinsZNF300 knockdown inhibits forced megakaryocytic differentiation by phorbol and erythrocytic differentiation by arabinofuranosyl cytidine in K562 cellsCD11c-mediated deletion of Flip promotes autoreactivity and inflammatory arthritis.Intracellular Tat of human immunodeficiency virus type 1 activates lytic cycle replication of Kaposi's sarcoma-associated herpesvirus: role of JAK/STAT signaling.STAT1 promotes megakaryopoiesis downstream of GATA-1 in miceBaicalein antagonizes acute megakaryoblastic leukemia in vitro and in vivo by inducing cell cycle arrestTyrosine 625 plays a key role and cooperates with tyrosine 630 in MPL W515L-induced signaling and myeloproliferative neoplasms.The ubiquitin E3 ligase TRAF6 exacerbates pathological cardiac hypertrophy via TAK1-dependent signalling.Survivin is not required for the endomitotic cell cycle of megakaryocytesGraded repression of PU.1/Sfpi1 gene transcription by GATA factors regulates hematopoietic cell fate.GATA-2 reinforces megakaryocyte development in the absence of GATA-1Novel function of the chromosome 7 open reading frame 41 gene to promote leukemic megakaryocyte differentiation by modulating TPA-induced signaling.The E3 ligase tripartite motif 8 targets TAK1 to promote insulin resistance and steatohepatitis.Vinexin β Ablation Inhibits Atherosclerosis in Apolipoprotein E-Deficient Mice by Inactivating the Akt-Nuclear Factor κB Inflammatory Axis.C1orf61 acts as a tumor activator in human hepatocellular carcinoma and is associated with tumorigenesis and metastasis.[AKT Is A Therapeutic Target in Myeloproliferative Neoplasms].Induction of INKIT by Viral Infection Negatively Regulates Antiviral Responses through Inhibiting Phosphorylation of p65 and IRF3.Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates.Dickkopf-3 Ablation Attenuates the Development of Atherosclerosis in ApoE-Deficient Mice.Overexpression of survivin initiates hematologic malignancies in vivoA continuous T-bet expression is required to silence the interleukin-4-producing potential in T helper type 1 cells.The deubiquitinating enzyme TNFAIP3 mediates inactivation of hepatic ASK1 and ameliorates nonalcoholic steatohepatitis.An ALOX12-12-HETE-GPR31 signaling axis is a key mediator of hepatic ischemia-reperfusion injury.The deubiquitinating enzyme cylindromatosis mitigates nonalcoholic steatohepatitis.The Ubiquitin E3 Ligase TRAF6 Exacerbates Ischemic Stroke by Ubiquitinating and Activating Rac1.Tetrandrine antagonizes acute megakaryoblastic leukaemia growth by forcing autophagy-mediated differentiation.ANP32A dysregulation contributes to abnormal megakaryopoiesis in acute megakaryoblastic leukemia.Tmbim1 is a multivesicular body regulator that protects against non-alcoholic fatty liver disease in mice and monkeys by targeting the lysosomal degradation of Tlr4.
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Zan Huang
@ast
Zan Huang
@en
Zan Huang
@es
Zan Huang
@nl
Zan Huang
@sl
type
label
Zan Huang
@ast
Zan Huang
@en
Zan Huang
@es
Zan Huang
@nl
Zan Huang
@sl
prefLabel
Zan Huang
@ast
Zan Huang
@en
Zan Huang
@es
Zan Huang
@nl
Zan Huang
@sl
P108
P106
P1153
55494520500
P31
P496
0000-0001-5623-6950