about
The Role of Serine Proteases and Antiproteases in the Cystic Fibrosis LungRespiratory syncytial virus infections enhance cigarette smoke induced COPD in miceConjugated linoleic acid and atherosclerosis: no effect on molecular markers of cholesterol homeostasis in THP-1 macrophages.Evaluation of the ability of LL-37 to neutralise LPS in vitro and ex vivo.miR-31 dysregulation in cystic fibrosis airways contributes to increased pulmonary cathepsin S production.Type-I interferons induce lung protease responses following respiratory syncytial virus infection via RIG-I-like receptors.A functional variant of elafin with improved anti-inflammatory activity for pulmonary inflammation.Functional study of elafin cleaved by Pseudomonas aeruginosa metalloproteinases.Decreased levels of secretory leucoprotease inhibitor in the Pseudomonas-infected cystic fibrosis lung are due to neutrophil elastase degradation.Elafin, an elastase-specific inhibitor, is cleaved by its cognate enzyme neutrophil elastase in sputum from individuals with cystic fibrosisInnate host defense functions of secretory leucoprotease inhibitor.SLPI and elafin: multifunctional antiproteases of the WFDC family.Secretory leucoprotease inhibitor binds to NF-kappaB binding sites in monocytes and inhibits p65 binding.Inhibition of ataxia telangiectasia related-3 (ATR) improves therapeutic index in preclinical models of non-small cell lung cancer (NSCLC) radiotherapy.The Ability of Secretory Leukocyte Protease Inhibitor to Inhibit Apoptosis in Monocytes Is Independent of Its Antiprotease Activity.The role of whey acidic protein four-disulfide-core proteins in respiratory health and disease.Activity of innate antimicrobial peptides and ivacaftor against clinical cystic fibrosis respiratory pathogens.Docosahexaenoic acid induces an anti-inflammatory profile in lipopolysaccharide-stimulated human THP-1 macrophages more effectively than eicosapentaenoic acid.Antiproteases as therapeutics to target inflammation in cystic fibrosis.LPS induced tissue factor expression in the THP-1 monocyte cell line is attenuated by conjugated linoleic acid.A secretory leukocyte protease inhibitor variant with improved activity against lung infection.A role for whey acidic protein four-disulfide-core 12 (WFDC12) in the regulation of the inflammatory response in the lung.Inflammation and host-pathogen interaction: Cause and consequence in cystic fibrosis lung disease.Characterisation of eppin function: expression and activity in the lung.Cystic fibrosis epithelial cells are primed for apoptosis as a result of increased Fas (CD95).Proteolytic cleavage of elafin by 20S proteasome may contribute to inflammation in acute lung injury.Glucocorticoid receptor β and histone deacetylase 1 and 2 expression in the airways of severe asthma.Proteases and Their Inhibitors in Chronic Obstructive Pulmonary DiseaseThe parasitic 68-mer peptide FhHDM-1 inhibits mixed granulocytic inflammation and airway hyperreactivity in experimental asthmaSea snake cathelicidin (Hc-cath) exerts a protective effect in mouse models of lung inflammation and infectionTargeting of cathepsin S reduces cystic fibrosis-like lung diseaseAt the forefront of cystic fibrosis Basic Science research: 16th ECFS Basic Science ConferencePreclinical Evaluation of Dose-Volume Effects and Lung Toxicity Occurring In and Out-of-FieldTargeting Proteases in Cystic Fibrosis Lung Disease. Paradigms, Progress, and PotentialProtein Phosphatase 2A Reduces Cigarette Smoke-induced Cathepsin S and Loss of Lung FunctionLack of IL-1 Receptor Signaling Reduces Spontaneous Airway Eosinophilia in Juvenile Mice with Muco-Obstructive Lung Disease
P50
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P50
description
hulumtuese
@sq
researcher
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wetenschapper
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հետազոտող
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name
Sinead Weldon
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Sinead Weldon
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Sinead Weldon
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Sinead Weldon
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Sinead Weldon
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type
label
Sinead Weldon
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Sinead Weldon
@en
Sinead Weldon
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Sinead Weldon
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Sinead Weldon
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prefLabel
Sinead Weldon
@ast
Sinead Weldon
@en
Sinead Weldon
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Sinead Weldon
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Sinead Weldon
@sl
P1053
J-5451-2014
P106
P21
P31
P3829
P496
0000-0001-5628-6624