P688
Association of HFE protein with transferrin receptor in crypt enterocytes of human duodenumThe hereditary hemochromatosis protein, HFE, specifically regulates transferrin-mediated iron uptake in HeLa cellsCrystal structure of the hereditary haemochromatosis protein HFE complexed with transferrin receptorHFE interacts with the BMP type I receptor ALK3 to regulate hepcidin expressionCo-localization of the mammalian hemochromatosis gene product (HFE) and a newly identified transferrin receptor (TfR2) in intestinal tissue and cellsTransferrin receptor co-localizes and interacts with the hemochromatosis factor (HFE) and the divalent metal transporter-1 (DMT1) in trophoblast cellsThe hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand bindingA novel MHC class I-like gene is mutated in patients with hereditary haemochromatosisHFE association with transferrin receptor 2 increases cellular uptake of transferrin-bound ironA time course of hepcidin response to iron challenge in patients with HFE and TFR2 hemochromatosisCrystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptorThe hemochromatosis proteins HFE, TfR2, and HJV form a membrane-associated protein complex for hepcidin regulationThe WT hemochromatosis protein HFE inhibits CD8⁺ T-lymphocyte activation
P921
Q22001443-A98D038F-83FD-43E0-9A68-8DDAD565A806Q22009072-92F51F02-55E6-46F8-9D2A-2630B5DE232FQ22011090-A3F47A97-B5B2-4E13-BE0A-548350DA58CEQ24298843-3E939D1F-B4C8-4255-9CEE-FC94DD345543Q24300212-6441F546-2A37-4936-A98B-0B531E3A1507Q24301644-1F2B9535-3EF0-41AB-ACA4-767DAC3C8718Q24309651-BF252911-AEF9-4DF1-8A24-594855CBADBEQ24310146-1D264CB5-52C8-48DA-BFFF-43D112A12114Q24312763-B0246290-CC09-442E-8215-59252E6B3AA8Q24318821-2F5B39C2-7641-4AEB-B9CE-4FC4F7E49955Q24336313-CCB5F1CE-F6F4-4B7B-A1A0-939E274360BCQ24338877-98BF6E76-1E02-4A7B-82B8-3C253CCF578AQ24339411-A37B53B2-032A-4F1D-BBE0-34CD965BDE8A
P921
description
Protein
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteína
@es
proteïne in Homeostatic iron regulator
@nl
protèin
@ace
protéine
@fr
بروتين في الإنسان العاقل
@ar
name
Gen HFE
@sl
HFE
@cy
HFE
@es
HFE
@fr
HFE
@uk
Hereditäre-Hämochromatose-Protein
@de
Homeostatic iron regulator
@en
type
label
Gen HFE
@sl
HFE
@cy
HFE
@es
HFE
@fr
HFE
@uk
Hereditäre-Hämochromatose-Protein
@de
Homeostatic iron regulator
@en
altLabel
HFE
@en
HFE
@sl
HLA-H
@en
Hämochromatose-Protein
@de
MHC class I-like protein HFE
@en
hereditary hemochromatosis protein HLA-H
@en
hereditary hemochromatosis protein
@en
high Fe
@en
prefLabel
Gen HFE
@sl
HFE
@cy
HFE
@es
HFE
@fr
HFE
@uk
Hereditäre-Hämochromatose-Protein
@de
Homeostatic iron regulator
@en
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P2888
P31
P352
P361
P486
D000071020
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P637
NP_001287678
NP_001371093
P672
D12.776.395.550.489.200
D12.776.543.550.439.200
D23.050.301.500.100.363
D23.050.705.552.100.375
P680
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ENSP00000259699
ENSP00000311698
ENSP00000312342
ENSP00000313776
ENSP00000315936
ENSP00000337819
ENSP00000380217
ENSP00000417404
ENSP00000417534
ENSP00000419725