Systems pharmacology identifies drug targets for Stargardt disease-associated retinal degeneration
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Sarpogrelate, a 5-HT2A Receptor Antagonist, Protects the Retina From Light-Induced RetinopathyG Protein-Coupled Receptor (GPCR) Expression in Native Cells: "Novel" endoGPCRs as Physiologic Regulators and Therapeutic TargetsBiology and therapy of inherited retinal degenerative disease: insights from mouse modelsRetinal Neuroprotective Effects of Flibanserin, an FDA-Approved Dual Serotonin Receptor Agonist-AntagonistChemistry and biology of the initial steps in vision: the Friedenwald lecture.All-trans-retinal induces Bax activation via DNA damage to mediate retinal cell apoptosis.Serial block face-scanning electron microscopy: a method to study retinal degenerative phenotypes.Adrenergic and serotonin receptors affect retinal superoxide generation in diabetic mice: relationship to capillary degeneration and permeability.Manganese-Enhanced MRI for Preclinical Evaluation of Retinal Degeneration TreatmentsMolecular pharmacodynamics of emixustat in protection against retinal degeneration.Predicting Progression of ABCA4-Associated Retinal Degenerations Based on Longitudinal Measurements of the Leading Disease Front.Systems Pharmacology Links GPCRs with Retinal Degenerative Disorders.Serum levels of lipid metabolites in age-related macular degeneration.The impact of microRNA gene regulation on the survival and function of mature cell types in the eyeSynergistically acting agonists and antagonists of G protein-coupled receptors prevent photoreceptor cell degeneration.Retinoids and Retinal Diseases.Eyes on systems pharmacology.Inner and outer retinal changes in retinal degenerations associated with ABCA4 mutations.Transcriptome analysis reveals rod/cone photoreceptor specific signatures across mammalian retinas.A therapeutic combination of GPCR modulators that protects photoreceptors from degeneration.The Role of ERK1/2 Activation in Sarpogrelate-Mediated Neuroprotection.Human aging and disease: Lessons from age-related macular degeneration.New GABA modulators protect photoreceptor cells from light-induced degeneration in mouse models.A novel small molecule chaperone of rod opsin and its potential therapy for retinal degeneration.Blue light excited retinal intercepts cellular signaling.Expression of dopamine D2 and D3 receptors in the human retina revealed by positron emission tomography and targeted mass spectrometryVisual cycle proteins: Structure, function, and roles in human retinal diseaseLong-term intake of KW3110 prevents age-related chronic inflammation and retinal cell loss in physiologically aged mice
P2860
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P2860
Systems pharmacology identifies drug targets for Stargardt disease-associated retinal degeneration
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Systems pharmacology identifie ...... ssociated retinal degeneration
@en
Systems pharmacology identifie ...... ssociated retinal degeneration
@nl
type
label
Systems pharmacology identifie ...... ssociated retinal degeneration
@en
Systems pharmacology identifie ...... ssociated retinal degeneration
@nl
prefLabel
Systems pharmacology identifie ...... ssociated retinal degeneration
@en
Systems pharmacology identifie ...... ssociated retinal degeneration
@nl
P2093
P2860
P356
P1476
Systems pharmacology identifie ...... ssociated retinal degeneration
@en
P2093
Akiko Maeda
Debarshi Mustafi
Grazyna Palczewska
Marcin Golczak
Osamu Sawada
Tadao Maeda
Zhiqian Dong
P2860
P304
P356
10.1172/JCI69076
P407
P577
2013-11-15T00:00:00Z