Systems pharmacology identifies drug targets for Stargardt disease-associated retinal degeneration - Test2 - elhamkhani - TriplyDB

Systems pharmacology identifies drug targets for Stargardt disease-associated retinal degeneration

Systems pharmacology identifies drug targets for Stargardt disease-associated retinal degeneration

http://www.wikidata.org/entity/Q42818656

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Sarpogrelate, a 5-HT2A Receptor Antagonist, Protects the Retina From Light-Induced Retinopathy G Protein-Coupled Receptor (GPCR) Expression in Native Cells: "Novel" endoGPCRs as Physiologic Regulators and Therapeutic Targets Biology and therapy of inherited retinal degenerative disease: insights from mouse models Retinal Neuroprotective Effects of Flibanserin, an FDA-Approved Dual Serotonin Receptor Agonist-Antagonist Chemistry and biology of the initial steps in vision: the Friedenwald lecture.All-trans-retinal induces Bax activation via DNA damage to mediate retinal cell apoptosis.Serial block face-scanning electron microscopy: a method to study retinal degenerative phenotypes.Adrenergic and serotonin receptors affect retinal superoxide generation in diabetic mice: relationship to capillary degeneration and permeability.Manganese-Enhanced MRI for Preclinical Evaluation of Retinal Degeneration Treatments Molecular pharmacodynamics of emixustat in protection against retinal degeneration.Predicting Progression of ABCA4-Associated Retinal Degenerations Based on Longitudinal Measurements of the Leading Disease Front.Systems Pharmacology Links GPCRs with Retinal Degenerative Disorders.Serum levels of lipid metabolites in age-related macular degeneration.The impact of microRNA gene regulation on the survival and function of mature cell types in the eye Synergistically acting agonists and antagonists of G protein-coupled receptors prevent photoreceptor cell degeneration.Retinoids and Retinal Diseases.Eyes on systems pharmacology.Inner and outer retinal changes in retinal degenerations associated with ABCA4 mutations.Transcriptome analysis reveals rod/cone photoreceptor specific signatures across mammalian retinas.A therapeutic combination of GPCR modulators that protects photoreceptors from degeneration.The Role of ERK1/2 Activation in Sarpogrelate-Mediated Neuroprotection.Human aging and disease: Lessons from age-related macular degeneration.New GABA modulators protect photoreceptor cells from light-induced degeneration in mouse models.A novel small molecule chaperone of rod opsin and its potential therapy for retinal degeneration.Blue light excited retinal intercepts cellular signaling.Expression of dopamine D2 and D3 receptors in the human retina revealed by positron emission tomography and targeted mass spectrometry Visual cycle proteins: Structure, function, and roles in human retinal disease Long-term intake of KW3110 prevents age-related chronic inflammation and retinal cell loss in physiologically aged mice

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P2860

Systems pharmacology identifies drug targets for Stargardt disease-associated retinal degeneration

http://www.wikidata.org/entity/Q42818656

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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2013年论文

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2013年论文

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name

Systems pharmacology identifie ...... ssociated retinal degeneration

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Systems pharmacology identifie ...... ssociated retinal degeneration

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type

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Systems pharmacology identifie ...... ssociated retinal degeneration

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Systems pharmacology identifie ...... ssociated retinal degeneration

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Systems pharmacology identifie ...... ssociated retinal degeneration

@en

Systems pharmacology identifie ...... ssociated retinal degeneration

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Journal of Clinical Investigation

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Systems pharmacology identifie ...... ssociated retinal degeneration

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Akiko Maeda

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Debarshi Mustafi

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Grazyna Palczewska

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Marcin Golczak

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Osamu Sawada

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Tadao Maeda

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Yu Chen

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Zhiqian Dong

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P2860

Role of photoreceptor-specific retinol dehydrogenase in the retinoid cycle in vivo.

Clinical experience with guanfacine in long-term treatment of hypertension.

Clinical experience with guanfacine in long-term treatment of hypertension. Part II: adverse reactions to guanfacine.

Retinopathy in mice induced by disrupted all-trans-retinal clearance

Noninvasive two-photon imaging reveals retinyl ester storage structures in the eye

Systems pharmacology: network analysis to identify multiscale mechanisms of drug action

Oxygen sensing in retinal health and disease

Systems pharmacology of complex diseases

Mechanisms of age-related macular degeneration

Rhodopsin-mediated blue-light damage to the rat retina: effect of photoreversal of bleaching

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5119-5134

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scholarly article

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10.1172/JCI69076

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12

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123

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Krzysztof Palczewski

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2013-11-15T00:00:00Z

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24231350

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