Activation of the Rap1 guanine nucleotide exchange gene, CalDAG-GEF I, in BXH-2 murine myeloid leukemia.
about
RasGRP4 is a novel Ras activator isolated from acute myeloid leukemiaMegakaryocytes derived from embryonic stem cells implicate CalDAG-GEFI in integrin signaling.An essential role for RasGRP1 in mast cell function and IgE-mediated allergic responseMultiple roles of Rap1 in hematopoietic cells: complementary versus antagonistic functionsGuanine nucleotide exchange factors CalDAG-GEFI and CalDAG-GEFII are colocalized in striatal projection neuronsRap1GAP inhibits tumor growth in oropharyngeal squamous cell carcinomaHuman RAS superfamily proteins and related GTPases.Rap1 integrates tissue polarity, lumen formation, and tumorigenic potential in human breast epithelial cells.The Ras-related protein, Rap1A, mediates thrombin-stimulated, integrin-dependent glioblastoma cell proliferation and tumor growthRegulation and Function of the RasGRP Family of Ras Activators in Blood CellsThe role of Ras guanine nucleotide releasing protein 4 in Fc epsilonRI-mediated signaling, mast cell function, and T cell development.Rap1b regulates B cell development, homing, and T cell-dependent humoral immunity.DAG tales: the multiple faces of diacylglycerol--stereochemistry, metabolism, and signalingStructural Basis for the Failure of the C1 Domain of Ras Guanine Nucleotide Releasing Protein 2 (RasGRP2) to Bind Phorbol Ester with High Affinity.Rap1a null mice have altered myeloid cell functions suggesting distinct roles for the closely related Rap1a and 1b proteinsDifferential membrane binding and diacylglycerol recognition by C1 domains of RasGRPs.Active Rap1, a small GTPase that induces malignant transformation of hematopoietic progenitors, localizes in the nucleus and regulates protein expression.Thyroid-stimulating hormone/cAMP and glycogen synthase kinase 3beta elicit opposing effects on Rap1GAP stability.Relationships between Rap1b, affinity modulation of integrin alpha IIbbeta 3, and the actin cytoskeleton.Activation of clg, a novel dbl family guanine nucleotide exchange factor gene, by proviral insertion at evi24, a common integration site in B cell and myeloid leukemias.Rheb is in a high activation state and inhibits B-Raf kinase in mammalian cells.cAMP-dependent oncogenic action of Rap1b in the thyroid gland.
P2860
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P2860
Activation of the Rap1 guanine nucleotide exchange gene, CalDAG-GEF I, in BXH-2 murine myeloid leukemia.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Activation of the Rap1 guanine ...... BXH-2 murine myeloid leukemia.
@en
Activation of the Rap1 guanine ...... BXH-2 murine myeloid leukemia.
@nl
type
label
Activation of the Rap1 guanine ...... BXH-2 murine myeloid leukemia.
@en
Activation of the Rap1 guanine ...... BXH-2 murine myeloid leukemia.
@nl
prefLabel
Activation of the Rap1 guanine ...... BXH-2 murine myeloid leukemia.
@en
Activation of the Rap1 guanine ...... BXH-2 murine myeloid leukemia.
@nl
P2093
P2860
P356
P1476
Activation of the Rap1 guanine ...... BXH-2 murine myeloid leukemia.
@en
P2093
Copeland NG
Jenkins NA
Largaespada DA
von Lintig FC
P2860
P304
11804-11811
P356
10.1074/JBC.M008970200
P407
P577
2001-01-22T00:00:00Z