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Centromere-associated topoisomerase activity in bloodstream form Trypanosoma bruceiCentromere-associated repeat arrays on Trypanosoma brucei chromosomes are much more extensive than predictedEvaluating 5-nitrofurans as trypanocidal agents.Independent mechanisms recruit the cohesin loader protein NIPBL to sites of DNA damage.Trypanocidal activity of nitroaromatic prodrugs: current treatments and future perspectives.Repetitive DNA is associated with centromeric domains in Trypanosoma brucei but not Trypanosoma cruzi.Nifurtimox activation by trypanosomal type I nitroreductases generates cytotoxic nitrile metabolites.mRNA Quantification of NIPBL Isoforms A and B in Adult and Fetal Human Tissues, and a Potentially Pathological Variant Affecting Only Isoform A in Two Patients with Cornelia de Lange Syndrome.Synthesis and structure-activity relationships of nitrobenzyl phosphoramide mustards as nitroreductase-activated prodrugs.
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E-9811-2011
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0000-0001-6225-4047