Engineered biosynthesis of a novel amidated polyketide, using the malonamyl-specific initiation module from the oxytetracycline polyketide synthase.
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StreptomeDB: a resource for natural compounds isolated from Streptomyces speciesSynthetic biology of antimicrobial discoveryEvolution of polyketide synthases in bacteriaChemical biology of tetracycline antibioticsThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB — Systems and Chemical Biology, and has undergone the Journal's usual peer review process.Cloning and characterization of the ravidomycin and chrysomycin biosynthetic gene clustersHeterologous expression of the oxytetracycline biosynthetic pathway in Myxococcus xanthus.Biochemical analysis of the biosynthetic pathway of an anticancer tetracycline SF2575.Emerging strategies and integrated systems microbiology technologies for biodiscovery of marine bioactive compounds.Cyclization of aromatic polyketides from bacteria and fungiOxytetracycline biosynthesis.Characterization of FdmV as an amide synthetase for fredericamycin A biosynthesis in Streptomyces griseus ATCC 43944.The bacterial translation stress response.Alternative sigma factor over-expression enables heterologous expression of a type II polyketide biosynthetic pathway in Escherichia coli.Identification of a cluster-situated activator of oxytetracycline biosynthesis and manipulation of its expression for improved oxytetracycline production in Streptomyces rimosus.The Biosynthesis of Capuramycin-type Antibiotics: IDENTIFICATION OF THE A-102395 BIOSYNTHETIC GENE CLUSTER, MECHANISM OF SELF-RESISTANCE, AND FORMATION OF URIDINE-5'-CARBOXAMIDE.Genetics of Streptomyces rimosus, the oxytetracycline producer.Draft Genome Sequence of the Oxytetracycline-Producing Bacterium Streptomyces rimosus ATCC 10970.Decoding and engineering tetracycline biosynthesis.Heterologous expression systems for polyketide synthases.Engineered Streptomyces avermitilis host for heterologous expression of biosynthetic gene cluster for secondary metabolitesBioinformatics tools for genome mining of polyketide and non-ribosomal peptides.Strategies for the Discovery and Development of New Antibiotics from Natural Products: Three Case Studies.Gold- or Silver-Catalyzed Syntheses of Pyrones and Pyridine Derivatives: Mechanistic and Synthetic Aspects.Heterologous expression and manipulation of three tetracycline biosynthetic pathways.Investigation of early tailoring reactions in the oxytetracycline biosynthetic pathway.Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor.Warhead biosynthesis and the origin of structural diversity in hydroxamate metalloproteinase inhibitors.Heterologous expression of oxytetracycline biosynthetic gene cluster in Streptomyces venezuelae WVR2006 to improve production level and to alter fermentation process.Involvement of the Baeyer-Villiger Monooxygenase IfnQ in the Biosynthesis of Isofuranonaphthoquinone Scaffold of JBIR-76 and -77.Construction of a new class of tetracycline lead structures with potent antibacterial activity through biosynthetic engineering.Manipulation of two regulatory genes for efficient production of chromomycins in Streptomyces reseiscleroticus.
P2860
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P2860
Engineered biosynthesis of a novel amidated polyketide, using the malonamyl-specific initiation module from the oxytetracycline polyketide synthase.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Engineered biosynthesis of a n ...... racycline polyketide synthase.
@en
Engineered biosynthesis of a n ...... racycline polyketide synthase.
@nl
type
label
Engineered biosynthesis of a n ...... racycline polyketide synthase.
@en
Engineered biosynthesis of a n ...... racycline polyketide synthase.
@nl
prefLabel
Engineered biosynthesis of a n ...... racycline polyketide synthase.
@en
Engineered biosynthesis of a n ...... racycline polyketide synthase.
@nl
P2093
P2860
P1476
Engineered biosynthesis of a n ...... racycline polyketide synthase.
@en
P2093
Brian D Ames
Shiou-Chuan Tsai
Wenjun Zhang
P2860
P304
P356
10.1128/AEM.72.4.2573-2580.2006
P407
P577
2006-04-01T00:00:00Z