Reciprocal relationship between O6-methylguanine-DNA methyltransferase P140K expression level and chemoprotection of hematopoietic stem cells.
about
Repair of O4-alkylthymine by O6-alkylguanine-DNA alkyltransferases.Correction of murine β-thalassemia after minimal lentiviral gene transfer and homeostatic in vivo erythroid expansion.Foamy viral vector integration sites in SCID-repopulating cells after MGMTP140K-mediated in vivo selectionLong-term polyclonal and multilineage engraftment of methylguanine methyltransferase P140K gene-modified dog hematopoietic cells in primary and secondary recipientsEctopic HOXB4 overcomes the inhibitory effect of tumor necrosis factor-{alpha} on Fanconi anemia hematopoietic stem and progenitor cells.Amelioration of murine beta-thalassemia through drug selection of hematopoietic stem cells transduced with a lentiviral vector encoding both gamma-globin and the MGMT drug-resistance gene.In vivo selection of hematopoietic progenitor cells and temozolomide dose intensification in rhesus macaques through lentiviral transduction with a drug resistance gene.Semi-automated closed system manufacturing of lentivirus gene-modified haematopoietic stem cells for gene therapyEfficiency and safety of O⁶-methylguanine DNA methyltransferase (MGMT(P140K))-mediated in vivo selection in a humanized mouse modelMultifaceted roles of alkyltransferase and related proteins in DNA repair, DNA damage, resistance to chemotherapy, and research tools.Efficient in vivo regulation of cytidine deaminase expression in the haematopoietic system using a doxycycline-inducible lentiviral vector system.Mechanisms controlling titer and expression of bidirectional lentiviral and gammaretroviral vectors.Tightly regulated 'all-in-one' lentiviral vectors for protection of human hematopoietic cells from anticancer chemotherapy.Hematologic adverse events associated with temozolomide.F2A sequence linking MGMT(P140K) and MDR1 in a bicistronic lentiviral vector enables efficient chemoprotection of haematopoietic stem cells.
P2860
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P2860
Reciprocal relationship between O6-methylguanine-DNA methyltransferase P140K expression level and chemoprotection of hematopoietic stem cells.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
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name
Reciprocal relationship betwee ...... n of hematopoietic stem cells.
@en
Reciprocal relationship betwee ...... n of hematopoietic stem cells.
@nl
type
label
Reciprocal relationship betwee ...... n of hematopoietic stem cells.
@en
Reciprocal relationship betwee ...... n of hematopoietic stem cells.
@nl
prefLabel
Reciprocal relationship betwee ...... n of hematopoietic stem cells.
@en
Reciprocal relationship betwee ...... n of hematopoietic stem cells.
@nl
P2093
P2860
P1433
P1476
Reciprocal relationship betwee ...... n of hematopoietic stem cells.
@en
P2093
Amanda Watson
Axel Schambach
Chad E Harris
Christopher Baum
David A Williams
David Schleimer
Emily Broun
Geoffrey P Margison
Hartmut Geiger
Jamie Wilhelm
P2860
P304
P356
10.1158/0008-5472.CAN-08-0320
P407
P577
2008-08-01T00:00:00Z