Comparison of MAPK specificity across the ETS transcription factor family identifies a high-affinity ERK interaction required for ERG function in prostate cells.
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Regulation of endothelial homeostasis, vascular development and angiogenesis by the transcription factor ERGMAPK/ERK2 phosphorylates ERG at serine 283 in leukemic cells and promotes stem cell signatures and cell proliferation.ETS-targeted therapy: can it substitute for MEK inhibitors?The endothelial transcription factor ERG mediates Angiopoietin-1-dependent control of Notch signalling and vascular stability.Activation of mutant TERT promoter by RAS-ERK signaling is a key step in malignant progression of BRAF-mutant human melanomas.Role of L1CAM in the Regulation of the Canonical Wnt Pathway and Class I MAGE Genes.Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2.Thyroid transcription factor FOXE1 interacts with ETS factor ELK1 to co-regulate TERT.TERT promoter mutations in melanoma render TERT expression dependent on MAPK pathway activation.An Interaction with Ewing's Sarcoma Breakpoint Protein EWS Defines a Specific Oncogenic Mechanism of ETS Factors Rearranged in Prostate Cancer.An Elf2-like transcription factor acts as repressor of the mouse ecto-5'-nucleotidase gene expression in hepatic myofibroblasts.Golgi stress-induced transcriptional changes mediated by MAPK signaling and three ETS transcription factors regulate MCL1 splicing.Phosphorylation of the oncogenic transcription factor ERG in prostate cells dissociates polycomb repressive complex 2, allowing target gene activation.A bipolar role of the transcription factor ERG for cnidarian germ layer formation and apical domain patterning.Dynamic regulation of VEGF-inducible genes by an ERK/ERG/p300 transcriptional network.
P2860
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P2860
Comparison of MAPK specificity across the ETS transcription factor family identifies a high-affinity ERK interaction required for ERG function in prostate cells.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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name
Comparison of MAPK specificity ...... RG function in prostate cells.
@en
Comparison of MAPK specificity ...... RG function in prostate cells.
@nl
type
label
Comparison of MAPK specificity ...... RG function in prostate cells.
@en
Comparison of MAPK specificity ...... RG function in prostate cells.
@nl
prefLabel
Comparison of MAPK specificity ...... RG function in prostate cells.
@en
Comparison of MAPK specificity ...... RG function in prostate cells.
@nl
P2860
P1476
Comparison of MAPK specificity ...... ERG function in prostate cells
@en
P2093
Nagarathinam Selvaraj
Peter C Hollenhorst
P2860
P2888
P356
10.1186/S12964-015-0089-7
P407
P577
2015-02-19T00:00:00Z
P5875
P6179
1052195868