The T cell receptor-mediated phosphorylation of Pyk2 tyrosines 402 and 580 occurs via a distinct mechanism than other receptor systems.
about
CD28 and CD3 have complementary roles in T-cell traction forces.Functions of the FAK family kinases in T cells: beyond actin cytoskeletal rearrangement.Fyn inhibition rescues established memory and synapse loss in Alzheimer mice.Non-catalytic functions of Pyk2 and Fyn regulate late stage adhesion in human T cells.Proline-rich tyrosine kinase 2 controls PI3-kinase activation downstream of the T cell antigen receptor in human T cells.TCR-mediated functions are enhanced in activated peripheral blood T cells isolated from leucocyte reduction systems.Inhibition of Pyk2 blocks lung inflammation and injury in a mouse model of acute lung injuryStriatal-enriched protein-tyrosine phosphatase (STEP) regulates Pyk2 kinase activity.Exposure of Human CD4 T Cells to IL-12 Results in Enhanced TCR-Induced Cytokine Production, Altered TCR Signaling, and Increased Oxidative Metabolism.The focal adhesion kinase inhibitor PF-562,271 impairs primary CD4+ T cell activation.Focal adhesion kinase negatively regulates Lck function downstream of the T cell antigen receptor.Targeting Fyn Kinase in Alzheimer's Disease.A PLC-γ1 Feedback Pathway Regulates Lck Substrate Phosphorylation at the T-Cell Receptor and SLP-76 Complex.LFA-1 activates focal adhesion kinases FAK1/PYK2 to generate LAT-GRB2-SKAP1 complexes that terminate T-cell conjugate formationRole of increased guanosine triphosphate cyclohydrolase-1 expression and tetrahydrobiopterin levels upon T cell activation.Regulation of the tyrosine kinase Pyk2 by calcium is through production of reactive oxygen species in cytotoxic T lymphocytes.Sperm-oocyte contact induces outside-in signaling via PYK2 activation.Synaptotoxic Signaling by Amyloid Beta Oligomers in Alzheimer's Disease Through Prion Protein and mGluR5.The Amyloid-β Oligomer Hypothesis: Beginning of the Third Decade.
P2860
Q30572013-0D700A25-B00F-4928-9725-AC2B0661DF83Q34016697-E1C398D4-9FC5-42F9-BE37-AA6B3CBBAE17Q34464152-58E99454-A360-4035-B8C3-0B6F378679E8Q34541534-1B2B5F62-EC9D-4627-8449-ECED6087CBE1Q35005871-4DCC59D9-BD32-497C-8C80-19EED6DB8D46Q35071445-CF1D7754-DDF3-4CC5-8972-9852EE2648A1Q35744840-55775B5A-B649-4000-97F7-54E53D5027AEQ36033151-17A8449C-C98B-4028-9FFB-4207F5B27670Q36046409-1086BB9F-ACBE-437B-8CA1-C6186C1E7B42Q37146813-F80798D3-44A5-4A79-B01E-A7377AA5F74EQ37398394-4431FDCD-4DB5-4CD7-835B-85C42F162572Q38678555-D1590DE3-C0D4-4E94-9A93-7EBADBDA2F24Q38712356-11C9B7D6-167E-4A57-9FBD-E39E56DCB486Q41013111-1585B045-37A2-4186-8212-FBCDF2CCBFEEQ41907337-0F7274CA-6BFE-4D60-8E24-972562787604Q42413088-F857483A-4DC4-40E5-807F-BA71C20B255DQ46208390-CC006C17-FF86-4147-9E75-A7B2A4E7E583Q50138252-A2981360-D519-4DC0-AD5B-E5C4BF0B4FA5Q54977832-463319A8-96BD-4771-8601-CD55D59149BE
P2860
The T cell receptor-mediated phosphorylation of Pyk2 tyrosines 402 and 580 occurs via a distinct mechanism than other receptor systems.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
The T cell receptor-mediated p ...... m than other receptor systems.
@en
The T cell receptor-mediated p ...... m than other receptor systems.
@nl
type
label
The T cell receptor-mediated p ...... m than other receptor systems.
@en
The T cell receptor-mediated p ...... m than other receptor systems.
@nl
prefLabel
The T cell receptor-mediated p ...... m than other receptor systems.
@en
The T cell receptor-mediated p ...... m than other receptor systems.
@nl
P2093
P2860
P356
P1476
The T cell receptor-mediated p ...... m than other receptor systems.
@en
P2093
Jon C D Houtman
Michaela Collins
Mikaela Tremblay
Miranda Curtiss
Nicole Chapman
Paul B Rothman
P2860
P304
P356
10.1189/JLB.0409227
P577
2009-12-22T00:00:00Z