Monooxygenase activity of human liver in microsomal fractions of needle biopsy specimens.
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Molecular changes in hepatic metabolism and transport in cirrhosis and their functional importanceElucidation of xenobiotic metabolism pathways in human skin and human skin models by proteomic profilingSignificance of the (13)C-caffeine breath test for patients with cirrhosisUltra-performance liquid chromatography coupled to time-of-flight mass spectrometry for robust, high-throughput quantitative analysis of an automated metabolic stability assay, with simultaneous determination of metabolic data.Furafylline is a potent and selective inhibitor of cytochrome P450IA2 in man.Conjugation pathways in liver disease.A stereochemical investigation of the cytotoxicity of mianserin metabolites in vitro.A comparative study of the formation of chemically reactive drug metabolites by human liver microsomes.A form of cytochrome P450 in man, orthologous to form d in the rat, catalyses the O-deethylation of phenacetin and is inducible by cigarette smokingPhenacetin O-deethylase: an activity of a cytochrome P-450 showing genetic linkage with that catalysing the 4-hydroxylation of debrisoquine?The metabolism of 7-ethoxycoumarin in human liver microsomes and the effect of primary biliary cirrhosis: implications for studies of drug metabolism in liver disease.The effect of cigarette smoking on 7-ethoxyresorufin O-deethylase and other monooxygenase activities in human liver: analyses with monoclonal antibodiesComparison of the in vivo and in vitro rates of formation of the three main oxidative metabolites of antipyrine in man.Assay and characterisation of debrisoquine 4-hydroxylase activity of microsomal fractions of human liverAntipyrine elimination as a dynamic test of hepatic functional integrity in obstructive jaundice.Assessment of the drug metabolism capacity of the liver.The effect of alcoholic cirrhosis on the activities of microsomal aldrin epoxidase, 7-ethoxycoumarin O-de-ethylase and epoxide hydrolase, and on the concentrations of reduced glutathione in human liver.Induction of drug-metabolizing enzymes by tricyclic antidepressants in human liver: characterization and partial resolution of cytochromes P-450.Coumarin 7-hydroxylase activity in human liver microsomes. Properties of the enzyme and interspecies comparisons.Can the clinical course of cancer be influenced by non-antineoplastic drugs?Human hepatocytes as a key in vitro model to improve preclinical drug development.Species variation in the response of the cytochrome P-450-dependent monooxygenase system to inducers and inhibitors.Human cytochromes P-450.Antipyrine clearance and metabolite formation: the influence of liver volume and smoking.Evidence for an enzymatic defect in the 4-hydroxylation of debrisoquine by human liver.Tissue differences in the ontogeny of inducibility of drug-metabolizing enzymes by 3-methylcholanthrene in the rabbit.Inter-relatedness of some isoenzymes of cytochrome P-450 from rat, rabbit and human, determined with monoclonal antibodies.H3 receptor antagonist, thioperamide, inhibits adrenal steroidogenesis and histamine binding to adrenocortical microsomes and binds to cytochrome P450Attempts to phenotype human liver samples in vitro for debrisoquine 4-hydroxylase activity.An anti-peptide antibody targeted to a specific region of rat cytochrome P-450IA2 inhibits enzyme activity.Identification of a functionally conserved surface region of rat cytochromes P450IA.The site of general anaesthesia and cytochrome P450 oxygenases: similarities defined by straight chain and cyclic alcohols.Phenacetin O-deethylation by human liver microsomes: kinetics and propranolol inhibition.Quantitation of intrinsic drug-metabolizing capacity in human liver biopsy specimens: support for the intact-hepatocyte theory.Interlaboratory comparison of the assessment of P450 activities in human hepatic microsomal samples.Oxidative metabolism of carbazeran in vitro by liver cytosol of baboon and man.The metabolic activation of 4,4'-methylene-bis-(2-chlorobenzeneamine) to a bacterial mutagen by hepatic postmitochondrial supernatant from human and other species.Metabolism of diazepam and related benzodiazepines by human liver microsomes.Genetic and environmental regulation of aryl hydrocarbon hydroxylase in man: studies with liver, lung, placenta, and lymphocytes.Differences in metabolism of chemical carcinogens in cultured human epithelial tissues and cells.
P2860
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P2860
Monooxygenase activity of human liver in microsomal fractions of needle biopsy specimens.
description
1980 nî lūn-bûn
@nan
1980年の論文
@ja
1980年学术文章
@wuu
1980年学术文章
@zh
1980年学术文章
@zh-cn
1980年学术文章
@zh-hans
1980年学术文章
@zh-my
1980年学术文章
@zh-sg
1980年學術文章
@yue
1980年學術文章
@zh-hant
name
Monooxygenase activity of human liver in microsomal fractions of needle biopsy specimens.
@en
Monooxygenase activity of human liver in microsomal fractions of needle biopsy specimens.
@nl
type
label
Monooxygenase activity of human liver in microsomal fractions of needle biopsy specimens.
@en
Monooxygenase activity of human liver in microsomal fractions of needle biopsy specimens.
@nl
prefLabel
Monooxygenase activity of human liver in microsomal fractions of needle biopsy specimens.
@en
Monooxygenase activity of human liver in microsomal fractions of needle biopsy specimens.
@nl
P2093
P2860
P1476
Monooxygenase activity of human liver in microsomal fractions of needle biopsy specimens.
@en
P2093
P2860
P356
10.1111/J.1365-2125.1980.TB04790.X
P407
P577
1980-01-01T00:00:00Z