about
Effects of monobutyl and di(n-butyl) phthalate in vitro on steroidogenesis and Leydig cell aggregation in fetal testis explants from the rat: comparison with effects in vivo in the fetal rat and neonatal marmoset and in vitro in the humanProposed role for COUP-TFII in regulating fetal Leydig cell steroidogenesis, perturbation of which leads to masculinization disorders in rodentsInter-relationship between testicular dysgenesis and Leydig cell function in the masculinization programming window in the ratSelective ablation of the androgen receptor in mouse sertoli cells affects sertoli cell maturation, barrier formation and cytoskeletal developmentEnvironmental/lifestyle effects on spermatogenesisEffects of environmental pollutants on the reproduction and welfare of ruminantsTime-dependent and compartment-specific effects of in utero exposure to Di(n-butyl) phthalate on gene/protein expression in the fetal rat testis as revealed by transcription profiling and laser capture microdissection.The Maestro (Mro) gene is dispensable for normal sexual development and fertility in miceIntratubular germ cell neoplasia of the human testis: heterogeneous protein expression and relation to invasive potential.Fetal programming of adult Leydig cell function by androgenic effects on stem/progenitor cellsAndrogen action via testicular peritubular myoid cells is essential for male fertility.Critical androgen-sensitive periods of rat penis and clitoris development.Androgen action via testicular arteriole smooth muscle cells is important for Leydig cell function, vasomotion and testicular fluid dynamicsProlonged exposure to acetaminophen reduces testosterone production by the human fetal testis in a xenograft modelFoetal and post-natal exposure of sheep to sewage sludge chemicals disrupts sperm production in adulthood in a subset of animals.Is it time to end concerns over the estrogenic effects of bisphenol A?Xenografting of human fetal testis tissue: a new approach to study fetal testis development and germ cell differentiation.Dynamic changes in DNA modification states during late gestation male germ line development in the ratDeletion of androgen receptor in the smooth muscle of the seminal vesicles impairs secretory function and alters its responsiveness to exogenous testosterone and estradiolDiethylstilboestrol exposure does not reduce testosterone production in human fetal testis xenografts.Prostaglandins, masculinization and its disorders: effects of fetal exposure of the rat to the cyclooxygenase inhibitor- indomethacin.Anogenital distance plasticity in adulthood: implications for its use as a biomarker of fetal androgen actionIdentification in rats of a programming window for reproductive tract masculinization, disruption of which leads to hypospadias and cryptorchidismComparative effects of di(n-butyl) phthalate exposure on fetal germ cell development in the rat and in human fetal testis xenograftsReproduction Symposium: does grazing on biosolids-treated pasture pose a pathophysiological risk associated with increased exposure to endocrine disrupting compounds?Effects of di(n-butyl) phthalate exposure on foetal rat germ-cell number and differentiation: identification of age-specific windows of vulnerability.Effect of androgen treatment during foetal and/or neonatal life on ovarian function in prepubertal and adult rats.Sperm counts and fertility in men: a rocky road ahead. Science & Society Series on Sex and ScienceIn utero exposure to di(n-butyl) phthalate and testicular dysgenesis: comparison of fetal and adult end points and their dose sensitivity.Analgesic exposure in pregnant rats affects fetal germ cell development with inter-generational reproductive consequencesPeri-conceptional changes in maternal exposure to sewage sludge chemicals disturbs fetal thyroid gland development in sheepIn utero exposure to low doses of environmental pollutants disrupts fetal ovarian development in sheep.Perinatal germ cell development and differentiation in the male marmoset (Callithrix jacchus): similarities with the human and differences from the ratGerm cell differentiation in the marmoset (Callithrix jacchus) during fetal and neonatal life closely parallels that in the human.Exposure to chemical cocktails before or after conception--- the effect of timing on ovarian development.Testicular dysgenesis syndrome: mechanistic insights and potential new downstream effects.Foetal hypothalamic and pituitary expression of gonadotrophin-releasing hormone and galanin systems is disturbed by exposure to sewage sludge chemicals via maternal ingestion.Aquaporin 9 expression in the developing rat epididymis is modulated by steroid hormones.Effect of fetal or neonatal exposure to monobutyl phthalate (MBP) on testicular development and function in the marmosetMale fertility and strategies for fertility preservation following childhood cancer treatment.
P50
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P50
description
hulumtues
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onderzoeker
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researcher
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հետազոտող
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name
Richard M Sharpe
@ast
Richard M Sharpe
@en
Richard M Sharpe
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Richard M Sharpe
@nl
Richard M Sharpe
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type
label
Richard M Sharpe
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Richard M Sharpe
@en
Richard M Sharpe
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Richard M Sharpe
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Richard M Sharpe
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prefLabel
Richard M Sharpe
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Richard M Sharpe
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Richard M Sharpe
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Richard M Sharpe
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Richard M Sharpe
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P1053
D-2725-2013
P106
P21
P31
P3829
P496
0000-0003-1686-8085