The gamma-glutamylcysteine synthetase gene of Leishmania is essential and involved in response to oxidants.
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Interactions between BRCA2 and RAD51 for promoting homologous recombination in Leishmania infantumThe Leishmania nicotinamidase is essential for NAD+ production and parasite proliferationMultiple mutations in heterogeneous miltefosine-resistant Leishmania major population as determined by whole genome sequencingProteomic and genomic analyses of antimony resistant Leishmania infantum mutantInduction of a stringent metabolic response in intracellular stages of Leishmania mexicana leads to increased dependence on mitochondrial metabolismStage-dependent expression and up-regulation of trypanothione synthetase in amphotericin B resistant Leishmania donovaniIntrachromosomal amplification, locus deletion and point mutation in the aquaglyceroporin AQP1 gene in antimony resistant Leishmania (Viannia) guyanensisA rapid, efficient and economical method for generating leishmanial gene targeting constructs.Leishmania major methionine sulfoxide reductase A is required for resistance to oxidative stress and efficient replication in macrophages.Roles of Rad51 paralogs for promoting homologous recombination in Leishmania infantum.The genetic toolbox for Leishmania parasitesThe leishmanicidal activity of oleuropein is selectively regulated through inflammation- and oxidative stress-related genesIntrachromosomal tandem duplication and repeat expansion during attempts to inactivate the subtelomeric essential gene GSH1 in LeishmaniaTolerance to drug-induced cell death favours the acquisition of multidrug resistance in Leishmania.Polyamine-trypanothione pathway: an update.Redox biology of Leishmania and macrophage targeted nanoparticles for therapy.Interplay between a cytosolic and a cell surface carbonic anhydrase in pH homeostasis and acid tolerance of Leishmania.Biochemical and biophysical characterization of Leishmania donovani gamma-glutamylcysteine synthetaseProbing druggability and biological function of essential proteins in Leishmania combining facilitated null mutant and plasmid shuffle analyses.Sulfur mustard causes oxidative stress and depletion of antioxidants in muscles, livers, and kidneys of Wistar rats.Drug target validation of the trypanothione pathway enzymes through metabolic modelling.Compounds with potential activity against Mycobacterium tuberculosis.High-throughput Cos-Seq screen with intracellular Leishmania infantum for the discovery of novel drug-resistance mechanisms.Genomic and transcriptomic alterations in Leishmania donovani lines experimentally resistant to antileishmanial drugs.ABCI3 Is a New Mitochondrial ABC Transporter from Leishmania major Involved in Susceptibility to Antimonials and Infectivity.Biomarkers of antimony resistance: need for expression analysis of multiple genes to distinguish resistance phenotype in clinical isolates of Leishmania donovani.Generation and characterization of thiol-deficient Mycobacterium tuberculosis mutants
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P2860
The gamma-glutamylcysteine synthetase gene of Leishmania is essential and involved in response to oxidants.
description
2009 nî lūn-bûn
@nan
2009年の論文
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2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
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2009年學術文章
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name
The gamma-glutamylcysteine syn ...... olved in response to oxidants.
@en
The gamma-glutamylcysteine syn ...... olved in response to oxidants.
@nl
type
label
The gamma-glutamylcysteine syn ...... olved in response to oxidants.
@en
The gamma-glutamylcysteine syn ...... olved in response to oxidants.
@nl
prefLabel
The gamma-glutamylcysteine syn ...... olved in response to oxidants.
@en
The gamma-glutamylcysteine syn ...... olved in response to oxidants.
@nl
P2093
P2860
P921
P1476
The gamma-glutamylcysteine syn ...... olved in response to oxidants.
@en
P2093
Angana Mukherjee
Chantal Guimond
Gaétan Roy
P2860
P304
P356
10.1111/J.1365-2958.2009.06907.X
P407
P577
2009-10-08T00:00:00Z