Inflammatory skin and bowel disease linked to ADAM17 deletion.
about
Yip1 domain family, member 6 (Yipf6) mutation induces spontaneous intestinal inflammation in miceMutations in CSTA, encoding Cystatin A, underlie exfoliative ichthyosis and reveal a role for this protease inhibitor in cell-cell adhesionADAM and ADAMTS Family Proteins and Snake Venom Metalloproteinases: A Structural OverviewProtease inhibition as new therapeutic strategy for GI diseasesA Disintegrin and Metalloprotease (ADAM): Historical Overview of Their FunctionsGenetics and Therapeutics in Pediatric Ulcerative Colitis: the Past, Present and FutureRole of genetics in pediatric inflammatory bowel diseaseThe diagnostic approach to monogenic very early onset inflammatory bowel diseasePhosphatidylserine exposure is required for ADAM17 sheddase functionGenetics of inflammatory bowel disease from multifactorial to monogenic formsGenetic variation in IBD: progress, clues to pathogenesis and possible clinical utilityEpithelial inflammation resulting from an inherited loss-of-function mutation in EGFREpidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation.Ectodomain Shedding by ADAM17: Its Role in Neutrophil Recruitment and the Impairment of This Process during SepsisGenetic variants of Adam17 differentially regulate TGFβ signaling to modify vascular pathology in mice and humans.CNNdel: Calling Structural Variations on Low Coverage Data Based on Convolutional Neural NetworksiRHOM2-dependent regulation of ADAM17 in cutaneous disease and epidermal barrier functionExome sequencing finds a novel PCSK1 mutation in a child with generalized malabsorptive diarrhea and diabetes insipidusMutations in tetratricopeptide repeat domain 7A result in a severe form of very early onset inflammatory bowel disease.A review of the diverse genetic disorders in the Lebanese population: highlighting the urgency for community genetic services.Involvement of TNF-α converting enzyme in the development of psoriasis-like lesions in a mouse model.Dysbiosis and Staphylococcus aureus Colonization Drives Inflammation in Atopic Dermatitis.iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signalingThe Inflammasome and the Epidermal Growth Factor Receptor (EGFR) Are Involved in the Staphylococcus aureus-Mediated Induction of IL-1alpha and IL-1beta in Human Keratinocytes.Molecular mechanisms in genetically defined autoinflammatory diseases: disorders of amplified danger signaling.Maintaining intestinal health: the genetics and immunology of very early onset inflammatory bowel disease.Targeting ADAM-17 with an inhibitory monoclonal antibody has antitumour effects in triple-negative breast cancer cells.Loss of ADAM17-Mediated Tumor Necrosis Factor Alpha Signaling in Intestinal Cells Attenuates Mucosal Atrophy in a Mouse Model of Parenteral NutritionOpportunities and challenges of whole-genome and -exome sequencing.Primary Immunodeficiencies and Inflammatory Disease: A Growing Genetic Intersection.ADAM Proteases and Gastrointestinal Function.The ADAMs family of proteases as targets for the treatment of cancer.A Lactobacillus rhamnosus GG-derived soluble protein, p40, stimulates ligand release from intestinal epithelial cells to transactivate epidermal growth factor receptor.ADAM17 substrate release in proximal tubule drives kidney fibrosisImpact of exome sequencing in inflammatory bowel disease.Harnessing the natural inhibitory domain to control TNFα Converting Enzyme (TACE) activity in vivo.To grow or not to grow: hair morphogenesis and human genetic hair disordersCell-cell connectivity: desmosomes and disease.Proteases and the gut barrier.Interleukin-10 and interleukin-10-receptor defects in inflammatory bowel disease.
P2860
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P2860
Inflammatory skin and bowel disease linked to ADAM17 deletion.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh-hant
name
Inflammatory skin and bowel disease linked to ADAM17 deletion.
@en
Inflammatory skin and bowel disease linked to ADAM17 deletion.
@nl
type
label
Inflammatory skin and bowel disease linked to ADAM17 deletion.
@en
Inflammatory skin and bowel disease linked to ADAM17 deletion.
@nl
prefLabel
Inflammatory skin and bowel disease linked to ADAM17 deletion.
@en
Inflammatory skin and bowel disease linked to ADAM17 deletion.
@nl
P2093
P50
P356
P1476
Inflammatory skin and bowel disease linked to ADAM17 deletion.
@en
P2093
Amanda Walne
Dominic J Abrams
Edel A O'Toole
Franz Ruschendorf
Joanne E Martin
John I Harper
Keith Lindley
Paolo Biancheri
Thomas T MacDonald
Tom Vulliamy
P304
P356
10.1056/NEJMOA1100721
P407
P50
P577
2011-10-01T00:00:00Z