Pig-a gene mutation and micronucleated reticulocyte induction in rats exposed to tumorigenic doses of the leukemogenic agents chlorambucil, thiotepa, melphalan, and 1,3-propane sultone.
about
Comparison of in vitro and in vivo clastogenic potency based on benchmark dose analysis of flow cytometric micronucleus data.Persistence of cisplatin-induced mutagenicity in hematopoietic stem cells: implications for secondary cancer risk following chemotherapyInduction of Pig-a mutant erythrocytes in male and female rats exposed to 1,3-propane sultone, ethyl carbamate, or thiotepa.Comparison of male versus female responses in the Pig-a mutation assay.Rat Pig-a mutation assay responds to the genotoxic carcinogen ethyl carbamate but not the non-genotoxic carcinogen methyl carbamate.Both PIGA and PIGL mutations cause GPI-a deficient isolates in the Tk6 cell line.Applying the erythrocyte Pig-a assay concept to rat epididymal sperm for germ cell mutagenicity evaluation.Empirical analysis of BMD metrics in genetic toxicology part II: in vivo potency comparisons to promote reductions in the use of experimental animals for genetic toxicity assessment.Characterisation of an in vivo Pig-a gene mutation assay for use in regulatory toxicology studies.
P2860
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P2860
Pig-a gene mutation and micronucleated reticulocyte induction in rats exposed to tumorigenic doses of the leukemogenic agents chlorambucil, thiotepa, melphalan, and 1,3-propane sultone.
description
2014 nî lūn-bûn
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2014年の論文
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2014年学术文章
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2014年学术文章
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name
Pig-a gene mutation and micron ...... alan, and 1,3-propane sultone.
@en
Pig-a gene mutation and micron ...... alan, and 1,3-propane sultone.
@nl
type
label
Pig-a gene mutation and micron ...... alan, and 1,3-propane sultone.
@en
Pig-a gene mutation and micron ...... alan, and 1,3-propane sultone.
@nl
prefLabel
Pig-a gene mutation and micron ...... alan, and 1,3-propane sultone.
@en
Pig-a gene mutation and micron ...... alan, and 1,3-propane sultone.
@nl
P2093
P2860
P356
P1476
Pig-a gene mutation and micron ...... alan, and 1,3-propane sultone.
@en
P2093
Dorothea K Torous
James T Macgregor
Jared Mereness
Jeffrey C Bemis
John Cottom
Souk Phonethepswath
Stephen D Dertinger
Svetlana L Avlasevich
P2860
P304
P356
10.1002/EM.21846
P577
2014-01-21T00:00:00Z