CYP2A6*6, a novel polymorphism in cytochrome p450 2A6, has a single amino acid substitution (R128Q) that inactivates enzymatic activity.
about
Molecular cloning and functional analysis of nine cinnamyl alcohol dehydrogenase family members in Populus tomentosa.Advancing the medical management of epilepsy: disease modification and pharmacogenetics.The role of pharmacogenetically-variable cytochrome P450 enzymes in drug abuse and dependence.Associations of CYP2A6 genotype with smoking behaviors in southern China.Interindividual differences in nicotine metabolism and genetic polymorphisms of human CYP2A6.Association of catechol-o-methyl transferase gene polymorphism with prostate cancer and benign prostatic hyperplasia.Association of CYP2A6 deletion polymorphism with smoking habit and development of pulmonary emphysema.Genetic variability in CYP2A6 and the pharmacokinetics of nicotine.CYP2A6 polymorphisms and risk for tobacco-related cancers.Polymorphic metabolism by functional alterations of human cytochrome P450 enzymes.Distribution of polymorphic variants of CYP2A6 and their involvement in nicotine addiction.Characterization of a novel CYP2A7/CYP2A6 hybrid allele (CYP2A6*12) that causes reduced CYP2A6 activity.Genetic polymorphisms in human CYP2A6 gene causing impaired nicotine metabolismGenetic variants affecting equivalent protein family positions reflect human diversity.Novel and established CYP2A6 alleles impair in vivo nicotine metabolism in a population of Black African descent.Novel human CYP2A6 alleles confound gene deletion analysis.Cytochrome P450 1B1 polymorphisms and risk of renal cell carcinoma in men.Association of genetic polymorphisms CYP2A6*2 rs1801272 and CYP2A6*9 rs28399433 with tobacco-induced lung Cancer: case-control study in an Egyptian population.Point mutation of cytochrome P450 2A6 (a polymorphic variant CYP2A6.25) confers new substrate specificity towards flavonoids.Metabolism of 7-ethoxycoumarin, safrole, flavanone and hydroxyflavanone by cytochrome P450 2A6 variants.
P2860
Q33358883-62CA46A6-35D3-4C80-83E6-E5FB39463F4CQ34579490-BEBBA31C-E9A4-4C00-B371-0E021E3CA7CDQ34612112-E60C3624-E71C-4BE3-8DF0-7F1146A0F7D1Q34778875-183627F3-5E89-4F3C-9B10-1656D3C0DDDFQ35027945-C7ABB2D1-E9C7-47E9-BCC0-D97301ABCD83Q35084863-FD8685A2-C989-4977-AA87-556C520E5B19Q35536013-52B5588F-8800-4AA9-B5FF-9B77C572A99FQ36989832-582200AE-88D4-49EB-9CDD-E1503AC87442Q37329175-BFBB858B-4FAF-4D26-A980-6ADA095D203AQ37964573-0A0E69DC-FC5F-4976-80F6-61C5A44EFEE4Q38683483-0E0C7AF2-DC8F-4A70-A1A8-3032FED1A444Q40701329-1F58AECD-2FCF-4258-B2C7-D2487279B99CQ42284318-C9765866-8E03-4C53-B261-AFA2C17F8C45Q42371793-9910527B-92D8-4B75-88CF-0AFDA1BBC4FCQ43597583-E36BA531-ADA2-4A33-8ADC-E787CEF5F11BQ44957920-DBB3A7D4-464F-4B47-B163-8F424A338837Q51127565-C86C08FE-88BF-4A18-8E6F-EC70B47884EFQ53686438-0603C057-21B7-45BF-ADF4-565760B37B5DQ54263454-4C59CCDC-907C-458B-903A-05C2A297A7DDQ54324598-198171E6-27F3-4E53-8E81-70A1E2C96FB2
P2860
CYP2A6*6, a novel polymorphism in cytochrome p450 2A6, has a single amino acid substitution (R128Q) that inactivates enzymatic activity.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
CYP2A6*6, a novel polymorphism ...... nactivates enzymatic activity.
@en
CYP2A6*6, a novel polymorphism ...... nactivates enzymatic activity.
@nl
type
label
CYP2A6*6, a novel polymorphism ...... nactivates enzymatic activity.
@en
CYP2A6*6, a novel polymorphism ...... nactivates enzymatic activity.
@nl
prefLabel
CYP2A6*6, a novel polymorphism ...... nactivates enzymatic activity.
@en
CYP2A6*6, a novel polymorphism ...... nactivates enzymatic activity.
@nl
P2093
P2860
P356
P1476
CYP2A6*6, a novel polymorphism ...... nactivates enzymatic activity.
@en
P2093
K Kitagawa
M Kitagawa
T Kawamoto
P2860
P304
17830-17835
P356
10.1074/JBC.M009432200
P407
P577
2001-02-16T00:00:00Z