Determining the structure and mode of action of microbisporicin, a potent lantibiotic active against multiresistant pathogens.
about
Evolution of lanthipeptide synthetasesStructure-activity relationship studies of the two-component lantibiotic haloduracinBioengineering Lantibiotics for Therapeutic SuccessThe Lantibiotic NAI-107 Binds to Bactoprenol-bound Cell Wall Precursors and Impairs Membrane FunctionsLantibiotic resistance.Distinct mechanisms contribute to immunity in the lantibiotic NAI-107 producer strain Microbispora ATCC PTA-5024A relA-dependent regulatory cascade for auto-induction of microbisporicin production in Microbispora corallinaMicromonospora avicenniae sp. nov., isolated from a root of Avicennia marina.Dissecting structural and functional diversity of the lantibiotic mersacidinMicrobisporicin gene cluster reveals unusual features of lantibiotic biosynthesis in actinomycetes.Structural investigation of ribosomally synthesized natural products by hypothetical structure enumeration and evaluation using tandem MS.Antibiotic discovery in the twenty-first century: current trends and future perspectives.Micromonospora haikouensis sp. nov., isolated from mangrove soil.Verrucosispora wenchangensis sp. nov., isolated from mangrove soil.Cloning and analysis of the planosporicin lantibiotic biosynthetic gene cluster of Planomonospora alba.Saturation mutagenesis of lysine 12 leads to the identification of derivatives of nisin A with enhanced antimicrobial activity.Efficacy of the new lantibiotic NAI-107 in experimental infections induced by multidrug-resistant Gram-positive pathogens.In vivo pharmacokinetics and pharmacodynamics of the lantibiotic NAI-107 in a neutropenic murine thigh infection model.Improved lanthipeptide detection and prediction for antiSMASHBiosynthesis of the antimicrobial peptide epilancin 15X and its N-terminal lactatePseudomycoicidin, a Class II Lantibiotic from Bacillus pseudomycoides.The Lantibiotic Lacticin 3147 Prevents Systemic Spread of Staphylococcus aureus in a Murine Infection Model.Expanded natural product diversity revealed by analysis of lanthipeptide-like gene clusters in actinobacteriaDecarbonylative approach to the synthesis of enamides from amino acids: stereoselective synthesis of the (Z)-aminovinyl-D-cysteine unit of mersacidinElucidating the molecular physiology of lantibiotic NAI-107 production in Microbispora ATCC-PTA-5024.Micromonospora mangrovi sp. nov., isolated from mangrove soil.Chemical synthesis and biological activity of analogues of the lantibiotic epilancin 15X.A Novel Microbisporicin Producer Identified by Early Dereplication during Lantibiotic ScreeningOn Lactococcus lactis UL719 competitivity and nisin (Nisaplin(®)) capacity to inhibit Clostridium difficile in a model of human colon.Preparation of Specific Polyclonal Antibody Against the Recombinant Mutacin Produced by sfGFP Fusion Protein Technology.Structure and tRNA Specificity of MibB, a Lantibiotic Dehydratase from Actinobacteria Involved in NAI-107 Biosynthesis.The antibiotic planosporicin coordinates its own production in the actinomycete Planomonospora alba.Manipulation of charged residues within the two-peptide lantibiotic lacticin 3147.Ribosomal peptide natural products: bridging the ribosomal and nonribosomal worlds.The dawning of a 'Golden era' in lantibiotic bioengineering.Increasing the success rate of lantibiotic drug discovery by Synthetic Biology.Contribution of the Actinobacteria to the growing diversity of lantibiotics.Anti-infective properties of bacteriocins: an update.Viable screening targets related to the bacterial cell wall.Antimicrobial peptides: versatile biological properties.
P2860
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P2860
Determining the structure and mode of action of microbisporicin, a potent lantibiotic active against multiresistant pathogens.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
Determining the structure and ...... inst multiresistant pathogens.
@en
Determining the structure and ...... inst multiresistant pathogens.
@nl
type
label
Determining the structure and ...... inst multiresistant pathogens.
@en
Determining the structure and ...... inst multiresistant pathogens.
@nl
prefLabel
Determining the structure and ...... inst multiresistant pathogens.
@en
Determining the structure and ...... inst multiresistant pathogens.
@nl
P2093
P1476
Determining the structure and ...... ainst multiresistant pathogens
@en
P2093
Ameriga Lazzarini
Daniele Losi
Emiliana Corti
Enrico Selva
Flavia Marinelli
Francesco Parenti
Ismaela Ciciliato
Lucia Carrano
Luciano Gastaldo
Paolo Candiani
P356
10.1016/J.CHEMBIOL.2007.11.009
P577
2008-01-01T00:00:00Z