about
Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selectionRegnase-1 and Roquin Regulate a Common Element in Inflammatory mRNAs by Spatiotemporally Distinct MechanismsRoquin binds microRNA-146a and Argonaute2 to regulate microRNA homeostasisIL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses.Inflammation: gone with translation.The ROQUIN family of proteins localizes to stress granules via the ROQ domain and binds target mRNAs.Extrafollicular antibody responses.Breakdown in repression of IFN-γ mRNA leads to accumulation of self-reactive effector CD8+ T cells.T-cell subsets in the germinal center.Roquin-2 shares functions with its paralog Roquin-1 in the repression of mRNAs controlling T follicular helper cells and systemic inflammation.The molecular basis of lymphoid architecture and B cell responses: implications for immunodeficiency and immunopathology.Dendritic cells, BAFF, and APRIL: innate players in adaptive antibody responses.Logic and extent of miRNA-mediated control of autoimmune gene expression.B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cellsAnti-islet autoantibodies trigger autoimmune diabetes in the presence of an increased frequency of islet-reactive CD4 T cellsMicroRNA-146a regulates ICOS-ICOSL signalling to limit accumulation of T follicular helper cells and germinal centres.Foxp3+ follicular regulatory T cells control the germinal center response.Pathophysiology of T follicular helper cells in humans and miceCellular and genetic mechanisms of self tolerance and autoimmunity.Attenuation of AMPK signaling by ROQUIN promotes T follicular helper cell formation.Tolerance mechanisms in the late phase of the antibody response.Human SNP links differential outcomes in inflammatory and infectious disease to a FOXO3-regulated pathway.Follicular helper T cells are required for systemic autoimmunity.SiLEncing SLE: the power and promise of small noncoding RNAs.Dysregulation of germinal centres in autoimmune disease.Signals that influence T follicular helper cell differentiation and function.Multiple checkpoints keep follicular helper T cells under control to prevent autoimmunity.T cells and follicular dendritic cells in germinal center B-cell formation and selection.T follicular helper cells during immunity and tolerance.The elusive identity of T follicular helper cells.T-follicular helper cell differentiation and the co-option of this pathway by non-helper cells.Developing connections amongst key cytokines and dysregulated germinal centers in autoimmunity.Innate B cell helpers reveal novel types of antibody responses.Control of TFH cell numbers: why and how?Axon growth and guidance genes identify T-dependent germinal centre B cells.Posttranscriptional T cell gene regulation to limit Tfh cells and autoimmunity.ROQUIN signalling pathways in innate and adaptive immunity.T Follicular Helper Cells in Transplantation.IL-27 Directly Enhances Germinal Center B Cell Activity and Potentiates Lupus in Sanroque Mice.Modulation of Roquin Function in Myeloid Cells Reduces Mycobacterium tuberculosis-Induced Inflammation.
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Carola G. Vinuesa
@en
Vinuesa CG
@ast
Vinuesa CG
@es
Vinuesa CG
@nl
Vinuesa CG
@sl
type
label
Carola G. Vinuesa
@en
Vinuesa CG
@ast
Vinuesa CG
@es
Vinuesa CG
@nl
Vinuesa CG
@sl
altLabel
Vinuesa CG
@en
prefLabel
Carola G. Vinuesa
@en
Vinuesa CG
@ast
Vinuesa CG
@es
Vinuesa CG
@nl
Vinuesa CG
@sl
P1053
B-1108-2010
P106
P31
P3829
P496
0000-0001-9799-0298