HIV-1-specific CD4+ T cells are detectable in most individuals with active HIV-1 infection, but decline with prolonged viral suppression.
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CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tractHIV-1 Nef impairs MHC class II antigen presentation and surface expressionStimulation of HIV-specific cellular immunity by structured treatment interruption fails to enhance viral control in chronic HIV infectionPerforin-low memory CD8+ cells are the predominant T cells in normal humans that synthesize the beta -chemokine macrophage inflammatory protein-1betaDurable cytotoxic immune responses against gp120 elicited by recombinant SV40 vectors encoding HIV-1 gp120 +/- IL-15CD8+ T lymphocyte responses target functionally important regions of Protease and Integrase in HIV-1 infected subjectsT-cell therapies for HIVEffective T helper cell responses against retroviruses: are all clonotypes equal?A crucial role for infected-cell/antibody immune complexes in the enhancement of endogenous antiviral immunity by short passive immunotherapyFunctional impairment of central memory CD4 T cells is a potential early prognostic marker for changing viral load in SHIV-infected rhesus macaquesBroad Specificity of Virus-Specific CD4+ T-Helper-Cell Responses in Resolved Hepatitis C Virus InfectionHighly active antiretroviral therapy in human immunodeficiency virus type 1-infected children: analysis of cellular immune responsesStrong HIV-1-specific T cell responses in HIV-1-exposed uninfected infants and neonates revealed after regulatory T cell removalAssociation of differentiation state of CD4+ T cells and disease progression in HIV-1 perinatally infected childrenModeling of HIV-1 infection: insights to the role of monocytes/macrophages, latently infected T4 cells, and HAART regimesImpaired T(H)17 cell differentiation in subjects with autosomal dominant hyper-IgE syndromeHIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cellsT-helper-cell proliferative responses to whole-killed human immunodeficiency virus type 1 (HIV-1) and p24 antigens of different clades in HIV-1-infected subjects vaccinated with HIV-1 immunogen (Remune)Fundamentals and application of magnetic particles in cell isolation and enrichment: a reviewFully differentiated HIV-1 specific CD8+ T effector cells are more frequently detectable in controlled than in progressive HIV-1 infection.Near-infrared dyes for six-color immunophenotyping by laser scanning cytometry.Identification of key peptide-specific CD4+ T cell responses to human cytomegalovirus: implications for tracking antiviral populations.The role of cytokines which signal through the common gamma chain cytokine receptor in the reversal of HIV specific CD4(+) and CD8(+) T cell anergyImmunity to HIV-1 is influenced by continued natural exposure to exogenous virus.Immunization with single-cycle SIV significantly reduces viral loads after an intravenous challenge with SIV(mac)239.In vitro priming recapitulates in vivo HIV-1 specific T cell responses, revealing rapid loss of virus reactive CD4 T cells in acute HIV-1 infection.Immunodominant HIV-1 Cd4+ T cell epitopes in chronic untreated clade C HIV-1 infection.Cytomegalovirus-specific T cells persist at very high levels during long-term antiretroviral treatment of HIV disease.HIV controller CD4+ T cells respond to minimal amounts of Gag antigen due to high TCR avidity.Clinical, immunological and treatment-related factors associated with normalised CD4+/CD8+ T-cell ratio: effect of naïve and memory T-cell subsetsMemory responses in human immunodeficiency virus type 1-infected individuals with long-term viral load suppression are independent of CD4 cell nadir.Cycling memory CD4+ T cells in HIV disease have a diverse T cell receptor repertoire and a phenotype consistent with bystander activation.Protease cleavage sites in HIV-1 gp120 recognized by antigen processing enzymes are conserved and located at receptor binding sitesStrategies used by human immunodeficiency virus that allow persistent viral replication.Comprehensive characterization of MHC class II haplotypes in Mauritian cynomolgus macaques.HIV-1-specific CD4+ T lymphocyte turnover and activation increase upon viral rebound.Induction of Gag-specific CD4 T cell responses during acute HIV infection is associated with improved viral control.Immune escape mutations detected within HIV-1 epitopes associated with viral control during treatment interruptionHuman immunodeficiency virus-1 Nef expression induces intracellular accumulation of multivesicular bodies and major histocompatibility complex class II complexes: potential role of phosphatidylinositol 3-kinaseImmune reconstitution in HIV-1 infected subjects treated with potent antiretroviral therapy.
P2860
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P2860
HIV-1-specific CD4+ T cells are detectable in most individuals with active HIV-1 infection, but decline with prolonged viral suppression.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
HIV-1-specific CD4+ T cells ar ...... h prolonged viral suppression.
@en
HIV-1-specific CD4+ T cells ar ...... h prolonged viral suppression.
@nl
type
label
HIV-1-specific CD4+ T cells ar ...... h prolonged viral suppression.
@en
HIV-1-specific CD4+ T cells ar ...... h prolonged viral suppression.
@nl
prefLabel
HIV-1-specific CD4+ T cells ar ...... h prolonged viral suppression.
@en
HIV-1-specific CD4+ T cells ar ...... h prolonged viral suppression.
@nl
P2093
P356
P1433
P1476
HIV-1-specific CD4+ T cells ar ...... h prolonged viral suppression.
@en
P2093
Peterson DM
Pitcher CJ
Quittner C
P2888
P304
P356
10.1038/8400
P407
P577
1999-05-01T00:00:00Z