Mammary epithelial-specific expression of the integrin-linked kinase (ILK) results in the induction of mammary gland hyperplasias and tumors in transgenic mice.
about
The integrin-actin connection, an eternal love affairProliferation and apoptosis in mammary epithelium during the rat oestrous cycleIntegrin-linked kinase mediates bone morphogenetic protein 7-dependent renal epithelial cell morphogenesisIntegrin-linked kinase is a functional Mn2+-dependent protein kinase that regulates glycogen synthase kinase-3β (GSK-3beta) phosphorylationEMT tumorigenesis in the mouse mammary gland.The small molecule inhibitor QLT0267 Radiosensitizes squamous cell carcinoma cells of the head and neck.Mechanisms of the epithelial-mesenchymal transition by TGF-betaThe pathology of EMT in mouse mammary tumorigenesis.Identification and characterization of a novel integrin-linked kinase inhibitorCooperative signaling between Wnt1 and integrin-linked kinase induces accelerated breast tumor developmentTumor reversion: correction of malignant behavior by microenvironmental cuesMicroRNA-mediated upregulation of integrin-linked kinase promotes Src-induced tumor progression.Integrin-linked kinase (ILK) and its interactors: a new paradigm for the coupling of extracellular matrix to actin cytoskeleton and signaling complexesSuppression of Her2/neu expression through ILK inhibition is regulated by a pathway involving TWIST and YB-1Dominant negative retinoic acid receptor initiates tumor formation in mice.Functional Role of mTORC2 versus Integrin-Linked Kinase in Mediating Ser473-Akt Phosphorylation in PTEN-Negative Prostate and Breast Cancer Cell Lines.A compendium of the mouse mammary tumor biologist: from the initial observations in the house mouse to the development of genetically engineered mice.Elevated PI3K signaling drives multiple breast cancer subtypes.Role of cell adhesion signal molecules in hepatocellular carcinoma cell apoptosis.Parvin-beta inhibits breast cancer tumorigenicity and promotes CDK9-mediated peroxisome proliferator-activated receptor gamma 1 phosphorylation.Characterisation of integrin-linked kinase signalling in sporadic human colon cancerUsing Pharmacokinetic Profiles and Digital Quantification of Stained Tissue Microarrays as a Medium-Throughput, Quantitative Method for Measuring the Kinetics of Early Signaling Changes Following Integrin-Linked Kinase Inhibition in an In Vivo ModelIntegrin-Linked Kinase: It's Role in the Vascular System.The phosphatidyl inositol 3-kinase signaling network: implications for human breast cancer.Met synergizes with p53 loss to induce mammary tumors that possess features of claudin-low breast cancer.Urokinase-type Plasminogen Activator (uPA) is Inhibited with QLT0267 a Small Molecule Targeting Integrin-linked Kinase (ILK)The pathophysiology of epithelial-mesenchymal transition induced by transforming growth factor-beta in normal and malignant mammary epithelial cells.Transforming growth factor beta induces clustering of HER2 and integrins by activating Src-focal adhesion kinase and receptor association to the cytoskeletonContributions of integrin-linked kinase to breast cancer metastasis and tumourigenesis.JNK1 determines the oncogenic or tumor-suppressive activity of the integrin-linked kinase in human rhabdomyosarcomaSix1 expands the mouse mammary epithelial stem/progenitor cell pool and induces mammary tumors that undergo epithelial-mesenchymal transition.Epithelial-mesenchymal transition in mouse mammary tumorigenesis.There's something about ILK.Modification of mesenchymal stem cells for cardiac regeneration.Integrin-linked kinase 1: role in hormonal cancer progression.Integrin-linked kinase: not so 'pseudo' after all.Overexpression of integrin-linked kinase (ILK) is associated with tumor progression and an unfavorable prognosis in patients with colorectal cancer.Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional extracellular matrix.Optimizing stem cells for cardiac repair: Current status and new frontiers in regenerative cardiologyRole for integrin-linked kinase in mediating tubular epithelial to mesenchymal transition and renal interstitial fibrogenesis.
P2860
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P2860
Mammary epithelial-specific expression of the integrin-linked kinase (ILK) results in the induction of mammary gland hyperplasias and tumors in transgenic mice.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Mammary epithelial-specific ex ...... and tumors in transgenic mice.
@en
Mammary epithelial-specific expression of the integrin-linked kinase
@nl
type
label
Mammary epithelial-specific ex ...... and tumors in transgenic mice.
@en
Mammary epithelial-specific expression of the integrin-linked kinase
@nl
prefLabel
Mammary epithelial-specific ex ...... and tumors in transgenic mice.
@en
Mammary epithelial-specific expression of the integrin-linked kinase
@nl
P2093
P2860
P356
P1433
P1476
Mammary epithelial-specific ex ...... and tumors in transgenic mice
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1204910
P407
P50
P577
2001-10-01T00:00:00Z
P5875
P6179
1032591546