Entry into cells and selective degradation of tRNAs by a cytotoxic member of the RNase A family.
about
Barnase as a new therapeutic agent triggering apoptosis in human cancer cellsRibonucleases as novel chemotherapeutics : the ranpirnase exampleNucleoside modifications in the regulation of gene expression: focus on tRNARegulation of cell death by transfer RNAStructural Basis for Catalysis by OnconaseCytotoxic ribonucleases: molecular weapons and their targetsOnconase and amphinase, the antitumor ribonucleases from Rana pipiens oocytesA novel class of small RNAs: tRNA-derived RNA fragments (tRFs).Onconase responsive genes in human mesothelioma cells: implications for an RNA damaging therapeutic agent.Trop-2-targeting tetrakis-ranpirnase has potent antitumor activity against triple-negative breast cancerThe cytotoxic ribonuclease onconase targets RNA interference (siRNA).Determinants of eukaryal cell killing by the bacterial ribotoxin PrrC.A Humanized Anti-CD22-Onconase Antibody-Drug Conjugate Mediates Highly Potent Destruction of Targeted Tumor CellsOxidative folding and N-terminal cyclization of onconase.tRNA cleavage is a conserved response to oxidative stress in eukaryotes.Dissimilarity in the oxidative folding of onconase and ribonuclease A, two structural homologuesRanpirnase as a potential antitumor ribonuclease treatment for mesothelioma and other malignancies.Ribonucleases as potential modalities in anticancer therapyEvaluation of human pancreatic RNase as effector molecule in a therapeutic antibody platform.Activating transcription factor 3 is crucial for antitumor activity and to strengthen the antiviral properties of Onconase.Apoptotic regulation and tRNA.Antibody-enzyme fusion proteins for cancer therapy.Synonymous codons, ribosome speed, and eukaryotic gene expression regulation.Highly selective toxic and proapoptotic effects of two dimeric ribonucleases on thyroid cancer cells compared to the effects of doxorubicin.Combination of onconase and dihydroartemisinin synergistically suppresses growth and angiogenesis of non-small-cell lung carcinoma and malignant mesothelioma.Anti-gliomas Effect of Chlorotoxin-Conjugated Onconase at High Dose.A fusogenic dengue virus-derived peptide enhances antitumor efficacy of an antibody-ribonuclease fusion protein targeting the EGF receptor.Cell-free protein synthesis of a cytotoxic cancer therapeutic: Onconase production and a just-add-water cell-free system.Onconase mediated NFKβ downregulation in malignant pleural mesothelioma.Binase cleaves cellular noncoding RNAs and affects coding mRNAs.tRNA binds to cytochrome c and inhibits caspase activation.Remarkable enhancement of cytotoxicity of onconase and cepharanthine when used in combination on various tumor cell lines.RNA repair: an antidote to cytotoxic eukaryal RNA damageChlorotoxin-conjugated onconase as a potential anti-glioma drug.The systemic tumor response to RNase A treatment affects the expression of genes involved in maintaining cell malignancy.Mapping, phylogenetic and expression analysis of the RNase (RNase A) locus in cattle.Waste not, want not: a case for tRNA repair.Transfer RNA cleavages by onconase reveal unusual cleavage sites.The nuclear transport capacity of a human-pancreatic ribonuclease variant is critical for its cytotoxicity.Targeted therapeutic RNases (ImmunoRNases)
P2860
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P2860
Entry into cells and selective degradation of tRNAs by a cytotoxic member of the RNase A family.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Entry into cells and selective ...... member of the RNase A family.
@en
Entry into cells and selective ...... member of the RNase A family.
@nl
type
label
Entry into cells and selective ...... member of the RNase A family.
@en
Entry into cells and selective ...... member of the RNase A family.
@nl
prefLabel
Entry into cells and selective ...... member of the RNase A family.
@en
Entry into cells and selective ...... member of the RNase A family.
@nl
P2093
P2860
P356
P1476
Entry into cells and selective ...... member of the RNase A family.
@en
P2093
Kuslima Shogen
Ravi Sirdeshmukh
Richard J Youle
Stanislaw M Mikulski
Wojciech Ardelt
P2860
P304
15142-15146
P356
10.1074/JBC.M108115200
P407
P577
2002-02-11T00:00:00Z