Hydrogen peroxide activates NF-kappa B through tyrosine phosphorylation of I kappa B alpha and serine phosphorylation of p65: evidence for the involvement of I kappa B alpha kinase and Syk protein-tyrosine kinase.
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Inhibition of SRC tyrosine kinases suppresses activation of nuclear factor-kappa B, and serine and tyrosine phosphorylation of Ikappa B-alpha in lipopolysaccharide-stimulated RAW 264.7 macrophagesDigitoxin mimics gene therapy with CFTR and suppresses hypersecretion of IL-8 from cystic fibrosis lung epithelial cellsTranscriptomics: A Step behind the Comprehension of the Polygenic Influence on Oxidative Stress, Immune Deregulation, and Mitochondrial Dysfunction in Chronic Kidney DiseaseThe Reactive Oxygen Species in Macrophage Polarization: Reflecting Its Dual Role in Progression and Treatment of Human DiseasesROS and ROS-Mediated Cellular SignalingNonsteroidal anti-inflammatory agents differ in their ability to suppress NF-kappaB activation, inhibition of expression of cyclooxygenase-2 and cyclin D1, and abrogation of tumor cell proliferationIron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseasesNrf2 and NF-κB and Their Concerted Modulation in Cancer Pathogenesis and ProgressionBasic principles and emerging concepts in the redox control of transcription factorsNF-κB dependent and independent mechanisms of quartz-induced proinflammatory activation of lung epithelial cellsNF-κB potentiates caspase independent hydrogen peroxide induced cell deathPark7 interacts with p47(phox) to direct NADPH oxidase-dependent ROS production and protect against sepsisActivation of Syk by protein kinase C-delta regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via tyrosine phosphorylation of RelA/p65.Nuclear factor-kappaB activation via tyrosine phosphorylation of inhibitor kappaB-alpha is crucial for ciliary neurotrophic factor-promoted neurite growth from developing neurons.Syk tyrosine kinase participates in beta1-integrin signaling and inflammatory responses in airway epithelial cells.Transcriptional and Molecular Pathways Activated in Mesenteric Adipose Tissue and Intestinal Mucosa of Crohn's Disease Patients.Targeted disruption of NF-{kappa}B1 (p50) augments cigarette smoke-induced lung inflammation and emphysema in mice: a critical role of p50 in chromatin remodelingBisdemethylcurcumin and structurally related hispolon analogues of curcumin exhibit enhanced prooxidant, anti-proliferative and anti-inflammatory activities in vitro.SENP3-mediated de-conjugation of SUMO2/3 from promyelocytic leukemia is correlated with accelerated cell proliferation under mild oxidative stressBeauvericin, a cyclic peptide, inhibits inflammatory responses in macrophages by inhibiting the NF-κB pathway.Crotepoxide chemosensitizes tumor cells through inhibition of expression of proliferation, invasion, and angiogenic proteins linked to proinflammatory pathwayModification of the cysteine residues in IkappaBalpha kinase and NF-kappaB (p65) by xanthohumol leads to suppression of NF-kappaB-regulated gene products and potentiation of apoptosis in leukemia cellsButyrate attenuates lipopolysaccharide-induced inflammation in intestinal cells and Crohn's mucosa through modulation of antioxidant defense machinery.Inhibiting NF-κB activation by small molecules as a therapeutic strategy.Long-term neuroprotection from a potent redox-modulating metalloporphyrin in the rat.Critical role of H2O2 generated by NOX4 during cellular response under glucose deprivationRole of pro-oxidants and antioxidants in the anti-inflammatory and apoptotic effects of curcumin (diferuloylmethane).Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)Cutting edge: reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome.GSTM1 modulation of IL-8 expression in human bronchial epithelial cells exposed to ozoneNF-κB addiction and its role in cancer: 'one size does not fit all'.Crosstalk of reactive oxygen species and NF-κB signalingAnti-atherogenic effect of hydrogen sulfide by over-expression of cystathionine gamma-lyase (CSE) gene.Glucose modulation induces reactive oxygen species and increases P-glycoprotein-mediated multidrug resistance to chemotherapeutics.Recruitment of the adaptor protein Nck to PECAM-1 couples oxidative stress to canonical NF-κB signaling and inflammation.Altered ROS production, NF-κB activation and interleukin-6 gene expression induced by electrical stimulation in dystrophic mdx skeletal muscle cells3-Formylchromone interacts with cysteine 38 in p65 protein and with cysteine 179 in IκBα kinase, leading to down-regulation of nuclear factor-κB (NF-κB)-regulated gene products and sensitization of tumor cellsGossypin, a pentahydroxy glucosyl flavone, inhibits the transforming growth factor beta-activated kinase-1-mediated NF-kappaB activation pathway, leading to potentiation of apoptosis, suppression of invasion, and abrogation of osteoclastogenesis.S-allylmercaptocysteine reduces carbon tetrachloride-induced hepatic oxidative stress and necroinflammation via nuclear factor kappa B-dependent pathways in mice.Inflammatory cause of metabolic syndrome via brain stress and NF-κB.
P2860
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P2860
Hydrogen peroxide activates NF-kappa B through tyrosine phosphorylation of I kappa B alpha and serine phosphorylation of p65: evidence for the involvement of I kappa B alpha kinase and Syk protein-tyrosine kinase.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Hydrogen peroxide activates NF ...... d Syk protein-tyrosine kinase.
@en
Hydrogen peroxide activates NF ...... d Syk protein-tyrosine kinase.
@nl
type
label
Hydrogen peroxide activates NF ...... d Syk protein-tyrosine kinase.
@en
Hydrogen peroxide activates NF ...... d Syk protein-tyrosine kinase.
@nl
prefLabel
Hydrogen peroxide activates NF ...... d Syk protein-tyrosine kinase.
@en
Hydrogen peroxide activates NF ...... d Syk protein-tyrosine kinase.
@nl
P2093
P2860
P356
P1476
Hydrogen peroxide activates NF ...... d Syk protein-tyrosine kinase.
@en
P2093
Asok Mukhopadhyay
Bharat B Aggarwal
Ganapati H Mahabeleshwar
Sujay Singh
Yasunari Takada
P2860
P304
24233-24241
P356
10.1074/JBC.M212389200
P407
P50
P577
2003-04-23T00:00:00Z