A human serotonin transporter mutation causes constitutive activation of transport activity.
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Lack of association between the Serotonin Transporter Promoter Polymorphism (5-HTTLPR) and Panic Disorder: a systematic review and meta-analysisPlasma serotonin levels and the platelet serotonin transporterAllelic heterogeneity at the serotonin transporter locus (SLC6A4) confers susceptibility to autism and rigid-compulsive behaviorsSupport for the association between the rare functional variant I425V of the serotonin transporter gene and susceptibility to obsessive compulsive disorderFunctional Evaluations of Genes Disrupted in Patients with Tourette's Disorder.Defining the blanks--pharmacochaperoning of SLC6 transporters and ABC transportersNetworking in autism: leveraging genetic, biomarker and model system findings in the search for new treatmentsCysteine-scanning mutagenesis of serotonin transporter intracellular loop 2 suggests an alpha-helical conformationPhosphorylation of threonine residue 276 is required for acute regulation of serotonin transporter by cyclic GMPGlycosyl modification facilitates homo- and hetero-oligomerization of the serotonin transporter. A specific role for sialic acid residuesHow the serotonin story is being rewritten by new gene-based discoveries principally related to SLC6A4, the serotonin transporter gene, which functions to influence all cellular serotonin systems.Human serotonin transporter variants display altered sensitivity to protein kinase G and p38 mitogen-activated protein kinase.Unbiased simulations reveal the inward-facing conformation of the human serotonin transporter and Na(+) ion release.Kinase-dependent Regulation of Monoamine Neurotransmitter Transporters.Molecular mechanisms of SERT in platelets: regulation of plasma serotonin levels.Serotonin transporter missense mutation associated with a complex neuropsychiatric phenotype.Cyclic GMP-dependent stimulation of serotonin transport does not involve direct transporter phosphorylation by cGMP-dependent protein kinase.A neuronal nitric oxide synthase (NOS-I) haplotype associated with schizophrenia modifies prefrontal cortex function.Myristoylation of cGMP-dependent protein kinase dictates isoform specificity for serotonin transporter regulation.Regulation of monoamine transporters: Role of transporter phosphorylation.At diabetes-like concentration, glucose down-regulates the placental serotonin transport system in a cell-cycle-dependent mannerSerotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder.Nitric oxide donors inhibit 5-hydroxytryptamine (5-HT) uptake by the human 5-HT transporter (SERT).Ontogeny and regulation of the serotonin transporter: providing insights into human disorders.Signaling pathways take aim at neurotransmitter transporters.Gene-environment interaction and the genetics of depression.Platelet serotonergic markers as endophenotypes for obsessive-compulsive disorder.Serotonin transporters: implications for antidepressant drug development.Regulation of monoamine transporters: influence of psychostimulants and therapeutic antidepressants.Human serotonin transporter gene (SLC6A4) variants: their contributions to understanding pharmacogenomic and other functional G×G and G×E differences in health and disease.Anxiety and affective disorder comorbidity related to serotonin and other neurotransmitter systems: obsessive-compulsive disorder as an example of overlapping clinical and genetic heterogeneityControl of serotonin transporter phosphorylation by conformational state.Molecular mechanism of ion-ion and ion-substrate coupling in the Na+-dependent leucine transporter LeuT.Regulation of human organic anion transporter 1 by ANG II: involvement of protein kinase Calpha.Going with the flow: trafficking-dependent and -independent regulation of serotonin transport.Common and rare alleles of the serotonin transporter gene, SLC6A4, associated with Tourette's disorder.Targeted Re-Sequencing Approach of Candidate Genes Implicates Rare Potentially Functional Variants in Tourette Syndrome EtiologycGMP-dependent protein kinase Ialpha associates with the antidepressant-sensitive serotonin transporter and dictates rapid modulation of serotonin uptake.Relationship of genetic variability and depressive symptoms to adverse events after coronary artery bypass graft surgery.Pharmacogenomic implications of variants of monoaminergic-related genes in geriatric psychiatry.
P2860
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P2860
A human serotonin transporter mutation causes constitutive activation of transport activity.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
A human serotonin transporter ...... ivation of transport activity.
@en
A human serotonin transporter ...... ivation of transport activity.
@nl
type
label
A human serotonin transporter ...... ivation of transport activity.
@en
A human serotonin transporter ...... ivation of transport activity.
@nl
prefLabel
A human serotonin transporter ...... ivation of transport activity.
@en
A human serotonin transporter ...... ivation of transport activity.
@nl
P2093
P356
P1476
A human serotonin transporter ...... ivation of transport activity.
@en
P2093
Dennis L Murphy
Fusun Kilic
Gary Rudnick
P304
P356
10.1124/MOL.64.2.440
P577
2003-08-01T00:00:00Z