HOX genes regulate Rac1 activity in hematopoietic cells through control of Vav2 expression.

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Role of HOXA9 in leukemia: dysregulation, cofactors and essential targets Pbx3 and Meis1 cooperate through multiple mechanisms to support Hox-induced murine leukemia.Insulin-like growth factor 1 is a direct HOXA9 target important for hematopoietic transformation.

P2860

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P2860

HOX genes regulate Rac1 activity in hematopoietic cells through control of Vav2 expression.

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http://www.wikidata.org/entity/Q44694070

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2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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HOX genes regulate Rac1 activi ...... gh control of Vav2 expression.

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HOX genes regulate Rac1 activi ...... gh control of Vav2 expression.

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Item

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HOX genes regulate Rac1 activi ...... gh control of Vav2 expression.

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HOX genes regulate Rac1 activi ...... gh control of Vav2 expression.

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HOX genes regulate Rac1 activi ...... gh control of Vav2 expression.

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HOX genes regulate Rac1 activi ...... gh control of Vav2 expression.

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P1476

HOX genes regulate Rac1 activi ...... gh control of Vav2 expression.

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P2093

C Breitinger

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E Maethner

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K D Fischer

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K Schilling

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M-P Garcia-Cuellar

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R K Slany

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P2860

Identification and characterization of Hoxa9 binding sites in hematopoietic cells

Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL.

Leukemogenic transformation by HOXA cluster genes.

HoxA10 regulates transcription of the gene encoding transforming growth factor beta2 (TGFbeta2) in myeloid cells.

Hox genes in hematopoiesis and leukemogenesis.

Inhibition of Rac GTPase signaling and downstream prosurvival Bcl-2 proteins as combination targeted therapy in MLL-AF9 leukemia.

Microenvironment determines lineage fate in a human model of MLL-AF9 leukemia.

The role of Hox proteins in leukemogenesis: insights into key regulatory events in hematopoiesis.

Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia.

Growth factor-dependent activation of the Ras-Raf-MEK-MAPK pathway in the human pancreatic carcinoma cell line PANC-1 carrying activated K-ras: implications for cell proliferation and cell migration.

P2888

leu.2012.166

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236-238

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scholarly article

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10.1038/LEU.2012.166

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Alexandra Schambony

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2012-06-20T00:00:00Z

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HOX genes regulate Rac1 activity in hematopoietic cells through control of Vav2 expression.

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P2860

P2860

HOX genes regulate Rac1 activity in hematopoietic cells through control of Vav2 expression.

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