about
Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemiaCooperative interaction between ETS1 and GFI1 transcription factors in the repression of Bax gene expressionRUNX1 regulates the CD34 gene in haematopoietic stem cells by mediating interactions with a distal regulatory elementMolecular cloning of the human eosinophil-derived neurotoxin: a member of the ribonuclease gene familyDifferential regulation of the human and murine CD34 genes in hematopoietic stem cells.CD34 is required for dendritic cell trafficking and pathology in murine hypersensitivity pneumonitisCell-cycle regulator E2F1 and microRNA-223 comprise an autoregulatory negative feedback loop in acute myeloid leukemiaCCAAT/enhancer binding protein epsilon is preferentially up-regulated during granulocytic differentiation and its functional versatility is determined by alternative use of promoters and differential splicingInduced pluripotent stem cells in hematology: current and future applicationsEGFR mutation and resistance of non-small-cell lung cancer to gefitinib.PU.1 (Spi-1) autoregulates its expression in myeloid cellsInduction of granulocytic differentiation by 2 pathwaysLocalization of the human eosinophil Charcot-Leyden crystal protein (lysophospholipase) gene (CLC) to chromosome 19 and the human ribonuclease 2 (eosinophil-derived neurotoxin) and ribonuclease 3 (eosinophil cationic protein) genes (RNS2 and RNS3) tTargeting transcription factor SALL4 in acute myeloid leukemia by interrupting its interaction with an epigenetic complexOncofetal gene SALL4 in aggressive hepatocellular carcinomaA disrupted RNA editing balance mediated by ADARs (Adenosine DeAminases that act on RNA) in human hepatocellular carcinomaA SALL4/MLL/HOXA9 pathway in murine and human myeloid leukemogenesisSALL4 is a new target in endometrial cancerIdentification and characterization of a functional promoter region in the human eosinophil IL-5 receptor alpha subunit geneEnhancement of hematopoietic stem cell repopulating capacity and self-renewal in the absence of the transcription factor C/EBP alphaC/EBP and DEK coordinately regulate myeloid differentiationTransgenic targeting with regulatory elements of the human CD34 gene.Distal elements are critical for human CD34 expression in vivo.The ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations.Down regulation of PSA by C/EBPalpha is associated with loss of AR expression and inhibition of PSA promoter activity in the LNCaP cell lineNOTCH2 and FLT3 gene mis-splicings are common events in patients with acute myeloid leukemia (AML): new potential targets in AMLIdentification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia.Molecular cloning of the alpha subunit of human and guinea pig leukocyte adhesion glycoprotein Mo1: chromosomal localization and homology to the alpha subunits of integrinsSox4 is a key oncogenic target in C/EBPα mutant acute myeloid leukemiaRunx1 exon 6-related alternative splicing isoforms differentially regulate hematopoiesis in miceApoptosis induced by JAK2 inhibition is mediated by Bim and enhanced by the BH3 mimetic ABT-737 in JAK2 mutant human erythroid cells.Downregulation of RUNX1/CBFβ by MLL fusion proteins enhances hematopoietic stem cell self-renewal.BCR-ABL enhances differentiation of long-term repopulating hematopoietic stem cellsDisruption of the C/EBPα-miR-182 balance impairs granulocytic differentiation.c-Myc is a critical target for c/EBPalpha in granulopoiesis.In vivo generation of transplantable human hematopoietic cells from induced pluripotent stem cells.Elevated PIN1 expression by C/EBPalpha-p30 blocks C/EBPalpha-induced granulocytic differentiation through c-Jun in AMLUse of bicistronic vectors in combination with flow cytometry to screen for effective small interfering RNA target sequencesDevelopmental checkpoints of the basophil/mast cell lineages in adult murine hematopoiesis.Respiratory failure due to differentiation arrest and expansion of alveolar cells following lung-specific loss of the transcription factor C/EBPalpha in mice.
P50
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description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Daniel G Tenen
@ast
Daniel G Tenen
@en
Daniel G Tenen
@es
Daniel G Tenen
@fr
Daniel G Tenen
@nl
Daniel G Tenen
@sl
type
label
Daniel G Tenen
@ast
Daniel G Tenen
@en
Daniel G Tenen
@es
Daniel G Tenen
@fr
Daniel G Tenen
@nl
Daniel G Tenen
@sl
prefLabel
Daniel G Tenen
@ast
Daniel G Tenen
@en
Daniel G Tenen
@es
Daniel G Tenen
@fr
Daniel G Tenen
@nl
Daniel G Tenen
@sl
P106
P21
P31
P496
0000-0002-6423-3888