Mutations in exon 14 of dihydropyrimidine dehydrogenase and 5-Fluorouracil toxicity in Portuguese colorectal cancer patients.
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Can knowledge of germline markers of toxicity optimize dosing and efficacy of cancer therapy?Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related toxicity in cancer patientsPromoter methylation and large intragenic rearrangements of DPYD are not implicated in severe toxicity to 5-fluorouracil-based chemotherapy in gastrointestinal cancer patients.Dihydropyrimidine dehydrogenase polymorphisms and fluoropyrimidine toxicity: ready for routine clinical application within personalized medicine?Evaluation of predictive tests for screening for dihydropyrimidine dehydrogenase deficiency.DPYD IVS14+1G>A and 2846A>T genotyping for the prediction of severe fluoropyrimidine-related toxicity: a meta-analysis.Translating DPYD genotype into DPD phenotype: using the DPYD gene activity score.DPYD genotype-guided dose individualization to improve patient safety of fluoropyrimidine therapy: call for a drug label update.Polymorphism of TS 3'-UTR predicts survival of Chinese advanced gastric cancer patients receiving first-line capecitabine plus paclitaxel.
P2860
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P2860
Mutations in exon 14 of dihydropyrimidine dehydrogenase and 5-Fluorouracil toxicity in Portuguese colorectal cancer patients.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
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2004年学术文章
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2004年學術文章
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name
Mutations in exon 14 of dihydr ...... se colorectal cancer patients.
@en
Mutations in exon 14 of dihydr ...... se colorectal cancer patients.
@nl
type
label
Mutations in exon 14 of dihydr ...... se colorectal cancer patients.
@en
Mutations in exon 14 of dihydr ...... se colorectal cancer patients.
@nl
prefLabel
Mutations in exon 14 of dihydr ...... se colorectal cancer patients.
@en
Mutations in exon 14 of dihydr ...... se colorectal cancer patients.
@nl
P2093
P2860
P50
P1433
P1476
Mutations in exon 14 of dihydr ...... se colorectal cancer patients.
@en
P2093
Evaristo Sanches
José Guimarães dos Santos
Maria Fragoso
Maria L Pellon
Natália Salgueiro
Nuno Costa
Olga Sousa
P2860
P304
P356
10.1097/01.GIM.0000118061.66602.A5
P407
P577
2004-03-01T00:00:00Z
P6179
1004195290