Rapamycin unbalances the polarization of human macrophages to M1. - Test2 - elhamkhani - TriplyDB

Rapamycin unbalances the polarization of human macrophages to M1.

Rapamycin unbalances the polarization of human macrophages to M1.

http://www.wikidata.org/entity/Q45057583

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Double Roles of Macrophages in Human Neuroimmune Diseases and Their Animal Models Current Concept and Update of the Macrophage Plasticity Concept: Intracellular Mechanisms of Reprogramming and M3 Macrophage "Switch" Phenotype The Complexity of Targeting PI3K-Akt-mTOR Signalling in Human Acute Myeloid Leukaemia: The Importance of Leukemic Cell Heterogeneity, Neighbouring Mesenchymal Stem Cells and Immunocompetent Cells The role of macrophage polarization in infectious and inflammatory diseases The Fate of the Tumor in the Hands of Microenvironment: Role of TAMs and mTOR Pathway.High-dose dexamethasone or all-trans retinoic acid restores the balance of macrophage toward M2 in Immune thrombocytopenia.Brucella Dysregulates Monocytes and Inhibits Macrophage Polarization through LC3-Dependent Autophagy.mTOR signaling inhibition modulates macrophage/microglia-mediated neuroinflammation and secondary injury via regulatory T cells after focal ischemia.Overnutrition, mTOR signaling, and cardiovascular diseases.Variation of transaminases, HCV-RNA levels and Th1/Th2 cytokine production during the post-partum period in pregnant women with chronic hepatitis C.Spatial and cellular characterization of mTORC1 activation after spinal cord injury reveals biphasic increase mainly attributed to microglia/macrophages.Effects of the mTOR inhibitor rapamycin on monocyte-secreted chemokines Tumor microenvironment: a new treatment target for cancer Functional TRAIL receptors in monocytes and tumor-associated macrophages: A possible targeting pathway in the tumor microenvironment mTORC2 signalling regulates M2 macrophage differentiation in response to helminth infection and adaptive thermogenesis Activation of mTOR (mechanistic target of rapamycin) in rheumatic diseases.Activation of the Mechanistic Target of Rapamycin in SLE: Explosion of Evidence in the Last Five Years.High-Fat Diet Induces Unexpected Fatal Uterine Infections in Mice with aP2-Cre-mediated Deletion of Estrogen Receptor Alpha.Macrophage phenotypes in atherosclerosis.The possible interaction between periostin expressed by cancer stroma and tumor-associated macrophages in developing mycosis fungoides.Regulation of innate immune cell function by mTOR.A neuropeptide, Substance-P, directly induces tissue-repairing M2 like macrophages by activating the PI3K/Akt/mTOR pathway even in the presence of IFNγ.PTEN/PI3k/AKT Regulates Macrophage Polarization in Emphysematous mice.The mechanism of synergistic effects of arsenic trioxide and rapamycin in acute myeloid leukemia cell lines lacking typical t(15;17) translocation.Synergistic immunologic targets for the treatment of prostate cancer.Akt Signaling Pathway in Macrophage Activation and M1/M2 Polarization.AKT/PKB Signaling: Navigating the Network.The TORC1-activated Proteins, p70S6K and GRB10, Regulate IL-4 Signaling and M2 Macrophage Polarization by Modulating Phosphorylation of Insulin Receptor Substrate-2.MenTORing Immunity: mTOR Signaling in the Development and Function of Tissue-Resident Immune Cells.Modulation of actin dynamics as potential macrophage subtype-targeting anti-tumour strategy.Sustained inhibition of receptor tyrosine kinases and macrophage depletion by PLX3397 and rapamycin as a potential new approach for the treatment of MPNSTs.Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation.Commentary: IL-4 and IL-13 receptors and signaling Advanced Glycation End Products Enhance Macrophages Polarization into M1 Phenotype through Activating RAGE/NF-κB Pathway.Macrophage Polarization Contributes to the Anti-Tumoral Efficacy of Mesoporous Nanovectors Loaded with Albumin-Bound Paclitaxel LncRNA GAS5 inhibits microglial M2 polarization and exacerbates demyelination.The mTOR kinase inhibitors polarize glioma-activated microglia to express a M1 phenotype.Liver damage, inflammation, and enhanced tumorigenesis after persistent mTORC1 inhibition.Hematopoietic stem cell transplantation rescues the immunologic phenotype and prevents vasculopathy in patients with adenosine deaminase 2 deficiency.Molecular Mechanisms Modulating the Phenotype of Macrophages and Microglia.

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P2860

Rapamycin unbalances the polarization of human macrophages to M1.

http://www.wikidata.org/entity/Q45057583

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2013 nî lūn-bûn

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2013年の論文

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2013年学术文章

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2013年学术文章

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2013年学术文章

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2013年学术文章

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2013年学术文章

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2013年學術文章

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2013年學術文章

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name

Rapamycin unbalances the polarization of human macrophages to M1.

@en

Rapamycin unbalances the polarization of human macrophages to M1.

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type

label

Rapamycin unbalances the polarization of human macrophages to M1.

@en

Rapamycin unbalances the polarization of human macrophages to M1.

@nl

prefLabel

Rapamycin unbalances the polarization of human macrophages to M1.

@en

Rapamycin unbalances the polarization of human macrophages to M1.

@nl

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Rapamycin unbalances the polarization of human macrophages to M1.

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P2093

Alessia Mercalli

http://www.w3.org/2001/XMLSchema#string

Antonio Secchi

http://www.w3.org/2001/XMLSchema#string

Elisa Cantarelli

http://www.w3.org/2001/XMLSchema#string

Ines Calavita

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Paola Maffi

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Raffaella Melzi

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Rita Nano

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P2860

Activating and inhibitory IgG Fc receptors on human DCs mediate opposing functions

Exploring the full spectrum of macrophage activation

TOR, a central controller of cell growth.

Rapamycin (AY-22,989), a new antifungal antibiotic. I. Taxonomy of the producing streptomycete and isolation of the active principle

Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen

Endoplasmic reticulum stress controls M2 macrophage differentiation and foam cell formation

Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression

Monocyte and macrophage heterogeneity

Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

mTOR and cancer: insights into a complex relationship

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179-190

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scholarly article

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10.1111/IMM.12126

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2

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140

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Lorenzo Piemonti

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2013-10-01T00:00:00Z

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236947324

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23710834

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