An aldol switch discovered in stilbene synthases mediates cyclization specificity of type III polyketide synthases.
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Biosynthesis of the active compounds of Isatis indigotica based on transcriptome sequencing and metabolites profilingPhenolic lipid synthesis by type III polyketide synthases is essential for cyst formation in Azotobacter vinelandiiExploiting the Biosynthetic Potential of Type III Polyketide SynthasesMechanism of inhibition of bovine F1-ATPase by resveratrol and related polyphenolsDistinct Structural Elements Dictate the Specificity of the Type III Pentaketide Synthase from Neurospora crassaA structure-based mechanism for benzalacetone synthase from Rheum palmatumStructural basis for the one-pot formation of the diarylheptanoid scaffold by curcuminoid synthase from Oryza sativaStructure of trans -Resveratrol in Complex with the Cardiac Regulatory Protein Troponin CCrystal Structure of Mycobacterium tuberculosis Polyketide Synthase 11 (PKS11) Reveals Intermediates in the Synthesis of Methyl-branched AlkylpyronesStructure/Function Analysis of a Type III Polyketide Synthase in the Brown Alga Ectocarpus siliculosus Reveals a Biochemical Pathway in Phlorotannin Monomer BiosynthesisStructural Basis for Cyclization Specificity of Two Azotobacter Type III Polyketide Synthases: A SINGLE AMINO ACID SUBSTITUTION REVERSES THEIR CYCLIZATION SPECIFICITYEngineering microbial factories for synthesis of value-added productsBiosynthesis of the major tetrahydroxystilbenes in spruce, astringin and isorhapontin, proceeds via resveratrol and is enhanced by fungal infectionStructure-function relationships in plant phenylpropanoid biosynthesisA polyketide synthase of Plumbago indica that catalyzes the formation of hexaketide pyrones.The rise of chemodiversity in plants.Biosynthesis of plant-specific stilbene polyketides in metabolically engineered Escherichia coli.Structure and function of enzymes involved in the biosynthesis of phenylpropanoidsBiosynthesis of Dictyostelium discoideum differentiation-inducing factor by a hybrid type I fatty acid-type III polyketide synthase.Structural and biochemical elucidation of mechanism for decarboxylative condensation of beta-keto acid by curcumin synthaseEngineering synthetic recursive pathways to generate non-natural small molecules.Engineered polyketide biosynthesis and biocatalysis in Escherichia coli.In vitro synthesis of curcuminoids by type III polyketide synthase from Oryza sativa.Identifying and manipulating structural determinates linking catalytic specificities in terpene synthases.Characterization of olivetol synthase, a polyketide synthase putatively involved in cannabinoid biosynthetic pathway.Structural basis for the design of potent and species-specific inhibitors of 3-hydroxy-3-methylglutaryl CoA synthasesHigh-yield resveratrol production in engineered Escherichia coli.Evolutionary and functional analysis of mulberry type III polyketide synthases.Vascular dysfunction in aging: potential effects of resveratrol, an anti-inflammatory phytoestrogen.Crystallization and preliminary crystallographic analysis of an acridone-producing novel multifunctional type III polyketide synthase from Huperzia serrata.Crystallization and preliminary crystallographic analysis of a plant type III polyketide synthase that produces benzalacetoneOuter-sphere residues influence the catalytic activity of a chalcone synthase from Polygonum cuspidatumNature's assembly line: biosynthesis of simple phenylpropanoids and polyketides.Stilbene synthase gene transfer caused alterations in the phenylpropanoid metabolism of transgenic strawberry (Fragaria x ananassa)Evolving biosynthetic tangos negotiate mechanistic landscapes.Putting bugs to the blush: metabolic engineering for phenylpropanoid-derived products in microorganisms.Engineering microbes for plant polyketide biosynthesis.Synthetic approaches to oligomeric natural products.Convergent strategies in biosynthesis.Crystallization and preliminary X-ray diffraction studies of polyketide synthase-1 (PKS-1) from Cannabis sativa.
P2860
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P2860
An aldol switch discovered in stilbene synthases mediates cyclization specificity of type III polyketide synthases.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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name
An aldol switch discovered in ...... type III polyketide synthases.
@en
An aldol switch discovered in ...... type III polyketide synthases.
@nl
type
label
An aldol switch discovered in ...... type III polyketide synthases.
@en
An aldol switch discovered in ...... type III polyketide synthases.
@nl
prefLabel
An aldol switch discovered in ...... type III polyketide synthases.
@en
An aldol switch discovered in ...... type III polyketide synthases.
@nl
P2093
P1476
An aldol switch discovered in ...... type III polyketide synthases.
@en
P2093
Jean-Luc Ferrer
Joachim Schröder
Joseph P Noel
Marianne E Bowman
Michael B Austin
P304
P356
10.1016/J.CHEMBIOL.2004.05.024
P577
2004-09-01T00:00:00Z