truncated APC mutants destabilize the destruction complex - Test2 - elhamkhani - TriplyDB

truncated APC mutants destabilize the destruction complex

truncated APC mutants destabilize the destruction complex

http://www.wikidata.org/entity/Q45314408

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APC truncation mutants are not K63 polyubiquitinated APC truncation mutants have impaired AXIN binding

P361

Signaling by WNT in cancer

P527

Q45314410-45DE1A1F-0037-4018-B79D-7B971DB40351 Q45314411-EDA96B94-3F78-4688-9044-AF6A36E43C14

P361

Q45314406-67028430-95D1-4992-91B7-7B2F67BE7AD6

P527

truncated APC mutants destabilize the destruction complex

http://www.wikidata.org/entity/Q45314408

description

An instance of the biological ...... uction complex in Homo sapiens

@en

name

truncated APC mutants destabilize the destruction complex

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type

label

truncated APC mutants destabilize the destruction complex

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prefLabel

truncated APC mutants destabilize the destruction complex

@en

P2860

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P2860

Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

Wnt signaling and cancer

Colorectal cancer and genetic alterations in the Wnt pathway

The β-catenin destruction complex

XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos

Mutations of the APC (adenomatous polyposis coli) gene.

Reversible modification of adenomatous polyposis coli (APC) with K63-linked polyubiquitin regulates the assembly and activity of the β-catenin destruction complex.

The way Wnt works: components and mechanism.

P2888

reactome:R-HSA-4839744

P31

biological pathway

P361

Signaling by WNT in cancer

P3937

R-HSA-4839744

http://www.w3.org/2001/XMLSchema#string

P527

APC truncation mutants are not K63 polyubiquitinated

APC truncation mutants have impaired AXIN binding

P703