about
Glycine degradationUnknown hydroxyproline carrier transports cytosolic HPRO into the mitochondrial matrixPRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylateSpontaneous hydrolysis of 1-pyrroline-3-hydroxy-5-carboxylate to 4-OH-L-glutamate semialdehydeALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamatePXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG)HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvateMitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvateAn unknown carrier transports mitochondrial glyoxylate to the cytosolAn unknown carrier transports cytosolic glyoxylate to the peroxisomeglycine + O2 => glyoxylate + H2O2 + NH4+DDO oxidizes D-Asp to OAglyoxylate + alanine => glycine + pyruvateglyoxylate + NADPH + H+ => glycolate + NADP+PXMP2 trimer transports glycolate from cytosol to peroxisomal matrixHAO1 tetramer oxidizes glycolate to glyoxylateConversion of glyoxylate to oxalateLIPT2 transfers octanoyl group to GCSHLIAS:2(4Fe-4S) transforms octanoyl-K107-GCSH to lipoyl-K107-GCSHLIPT1 transfers lipoyl group from lipoyl-GCSH to DHsGNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC
P361
Q45317456-33059345-CE2C-4B16-8A56-5D2AE715DD7FQ50295132-6163ECCF-DC1B-4500-AF82-5FABA848C94AQ50295133-E0BDCED1-502D-4E0B-AFC0-24489E874ED7Q50295135-A3319735-97B5-4DAE-BE05-EB4A5CDBBE33Q50295136-2030BE04-03E4-4D3F-899D-3E0C82114489Q50295137-4018D773-DE1E-40D8-8779-400AC66A2D24Q50295138-005E88A8-9817-4FC4-B35F-6F3D12486C87Q50295139-00D72FE7-5E06-4606-A874-A0B906177C6EQ50295140-47BA97BE-2CCF-4FDB-A56E-43262256A6C4Q50295141-370C149C-C480-4123-906F-AB614F498498Q50295143-7E9B1802-398C-4FBF-A972-3D07E7EE8F2FQ50295144-6893D9EA-97B8-4B03-8BB3-219D3E4D5B5EQ50295146-A9920B6F-7F2D-4373-9D56-26EC1928AD70Q50295147-8F54AAD6-8A89-43A1-8060-6A32A10AAA39Q50295148-0FF66058-E7CA-4C8E-902C-A3BA8DF32873Q50295149-FAE831F6-BB22-45E8-AB19-45862E7BC248Q50295150-D31F2AB2-40E0-49A4-B2A9-DCC6381962A8Q50295155-10B13AB5-19B9-40D3-8DA8-2D829DC0E18AQ50295156-8C3DCF80-4F47-4221-AED3-57816543ABE0Q50295157-ECC12429-2B56-48DB-AA25-4D481E64EBDCQ50295158-EB208B20-51CF-438E-9ECB-43E71395D5CA
P361
description
An instance of the biological ...... ne degradation in Homo sapiens
@en
name
Glyoxylate metabolism and glycine degradation
@en
type
label
Glyoxylate metabolism and glycine degradation
@en
prefLabel
Glyoxylate metabolism and glycine degradation
@en
P527
P3937
R-HSA-389661