Phosphorylation of tau protein at sites Ser(396-404) is one of the earliest events in Alzheimer's disease and Down syndrome.
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Molecular Pathological Classification of Neurodegenerative Diseases: Turning towards Precision MedicineA human carboxypeptidase E/NF-α1 gene mutation in an Alzheimer's disease patient leads to dementia and depression in mice.Psychotic Alzheimer's disease is associated with gender-specific tau phosphorylation abnormalities.Amyloid and tau pathology of familial Alzheimer's disease APP/PS1 mouse model in a senescence phenotype background (SAMP8).Tau monoclonal antibody generation based on humanized yeast models: impact on Tau oligomerization and diagnosticsTau phosphorylation at serine 396 residue is required for hippocampal LTDHyperphosphorylation of intrinsically disordered tau protein induces an amyloidogenic shift in its conformational ensemble.Discovery of the first dual GSK3β inhibitor/Nrf2 inducer. A new multitarget therapeutic strategy for Alzheimer's diseaseRetinol (Vitamin A) Increases α-Synuclein, β-Amyloid Peptide, Tau Phosphorylation and RAGE Content in Human SH-SY5Y Neuronal Cell Line.Characterization of TauC3 antibody and demonstration of its potential to block tau propagationCharacterization of Early Pathological Tau Conformations and Phosphorylation in Chronic Traumatic Encephalopathy.The BET-Bromodomain Inhibitor JQ1 Reduces Inflammation and Tau Phosphorylation at Ser396 in the Brain of the 3xTg Model of Alzheimer's DiseaseMicrotubule stabilising peptides rescue tau phenotypes in-vivo.Deep Phosphoproteomic Measurements Pinpointing Drug Induced Protective Mechanisms in Neuronal Cells.Presence of a carboxy-terminal pseudorepeat and disease-like pseudohyperphosphorylation critically influence tau's interaction with microtubules in axon-like processes.Protein phosphorylation in neurodegeneration: friend or foe?T3D-959: A Multi-Faceted Disease Remedial Drug Candidate for the Treatment of Alzheimer's Disease.Behind the curtain of tauopathy: a show of multiple players orchestrating tau toxicity.Quantitative computational models of molecular self-assembly in systems biology.Physiological and Pathophysiological Implications of Synaptic Tau.The physiological phosphorylation of tau is critically changed in fetal brains of individuals with Down syndrome.Sterile Neuroinflammation and Strategies for Therapeutic InterventionProteinopathy, oxidative stress and mitochondrial dysfunction: cross talk in Alzheimer's disease and Parkinson's diseaseMitochondrial Metabolism Power SIRT2-Dependent Deficient Traffic Causing Alzheimer's-Disease Related Pathology.Houttuynia cordata Improves Cognitive Deficits in Cholinergic Dysfunction Alzheimer's Disease-Like Models.Generation and characterization of new monoclonal antibodies targeting the PHF1 and AT8 epitopes on human tau.Haloperidol inactivates AMPK and reduces tau phosphorylation in a tau mouse model of Alzheimer's diseaseAdrenomedullin Contributes to Age-Related Memory Loss in Mice and Is Elevated in Aging Human Brains.Neuronal exosomes reveal Alzheimer's disease biomarkers in Down syndrome.Tauopathies: Mechanisms and Therapeutic Strategies.Exosomal biomarkers in Down syndrome and Alzheimer's disease.Tau and neuroinflammation: What impact for Alzheimer's Disease and Tauopathies?Phosphorylation of tau protein correlates with changes in hippocampal theta oscillations and reduces hippocampal excitability in Alzheimer's model.Differential Hyperphosphorylation of Tau-S199, -T231 and -S396 in Organotypic Brain Slices of Alzheimer Mice. A Model to Study Early Tau Hyperphosphorylation Using Okadaic Acid.Alzheimer's Transgenic Model Is Characterized by Very Early Brain Network Alterations and β-CTF Fragment Accumulation: Reversal by β-Secretase Inhibition.Extracellular Forms of Aβ and Tau from iPSC Models of Alzheimer's Disease Disrupt Synaptic Plasticity.A Study of Amyloid-β and Phosphotau in Plaques and Neurons in the Hippocampus of Alzheimer's Disease Patients.Importance of GPCR-Mediated Microglial Activation in Alzheimer's Disease
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P2860
Phosphorylation of tau protein at sites Ser(396-404) is one of the earliest events in Alzheimer's disease and Down syndrome.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
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2014年学术文章
@zh
2014年学术文章
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2014年学术文章
@zh-hans
2014年学术文章
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2014年学术文章
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2014年學術文章
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name
Phosphorylation of tau protein at sites Ser
@nl
Phosphorylation of tau protein ...... r's disease and Down syndrome.
@en
type
label
Phosphorylation of tau protein at sites Ser
@nl
Phosphorylation of tau protein ...... r's disease and Down syndrome.
@en
prefLabel
Phosphorylation of tau protein at sites Ser
@nl
Phosphorylation of tau protein ...... r's disease and Down syndrome.
@en
P2093
P2860
P356
P1476
Phosphorylation of tau protein ...... r's disease and Down syndrome.
@en
P2093
J Luna-Muñoz
M C Acevedo-Aquino
S Mondragón-Rodríguez
S Williams
P2860
P304
P356
10.1111/NAN.12084
P50
P577
2014-02-01T00:00:00Z