Adenoviruses with Tcf binding sites in multiple early promoters show enhanced selectivity for tumour cells with constitutive activation of the wnt signalling pathway.
about
Targeting the Wnt pathway in human cancers: therapeutic targeting with a focus on OMP-54F28Efficient generation of double heterologous promoter controlled oncolytic adenovirus vectors by a single homologous recombination step in Escherichia coliFusion of the BCL9 HD2 domain to E1A increases the cytopathic effect of an oncolytic adenovirus that targets colon cancer cells.Pharmacological and genetic modulation of Wnt-targeted Cre-Lox-mediated gene expression in colorectal cancer cells.Replicating parvoviruses that target colon cancer cellsArmed therapeutic viruses: strategies and challenges to arming oncolytic viruses with therapeutic genes.Chapter One---Cancer terminator viruses and approaches for enhancing therapeutic outcomes.Gene Therapies for Cancer: Strategies, Challenges and Successes.Replication-selective oncolytic viruses in the treatment of cancer.Adenoviruses for treatment of cancer.Oncolytic adenoviruses as antiglioma agents.Targeting the Wnt signaling pathway to treat Barrett's esophagus.Therapeutic potential of replication-selective oncolytic adenoviruses on cells from familial and sporadic desmoid tumors.Adenoviral vector-based strategies for cancer therapy.Modular Cre/lox system and genetic therapeutics for colorectal cancer.A modified E2F-1 promoter improves the efficacy to toxicity ratio of oncolytic adenoviruses.Selective replication of E1B55K-deleted adenoviruses depends on enhanced E1A expression in cancer cells.5-Fluorocytosine increases the toxicity of Wnt-targeting replicating adenoviruses that express cytosine deaminase as a late gene.Radiation increases the activity of oncolytic adenovirus cancer gene therapy vectors that overexpress the ADP (E3-11.6K) protein.Targeting of autonomous parvoviruses to colon cancer by insertion of Tcf sites in the P4 promoter.
P2860
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P2860
Adenoviruses with Tcf binding sites in multiple early promoters show enhanced selectivity for tumour cells with constitutive activation of the wnt signalling pathway.
description
2002 nî lūn-bûn
@nan
2002年の論文
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2002年学术文章
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2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
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2002年學術文章
@zh-hant
name
Adenoviruses with Tcf binding ...... of the wnt signalling pathway.
@en
Adenoviruses with Tcf binding ...... of the wnt signalling pathway.
@nl
type
label
Adenoviruses with Tcf binding ...... of the wnt signalling pathway.
@en
Adenoviruses with Tcf binding ...... of the wnt signalling pathway.
@nl
prefLabel
Adenoviruses with Tcf binding ...... of the wnt signalling pathway.
@en
Adenoviruses with Tcf binding ...... of the wnt signalling pathway.
@nl
P2860
P356
P1433
P1476
Adenoviruses with Tcf binding ...... of the wnt signalling pathway.
@en
P2860
P2888
P304
P356
10.1038/SJ.GT.3301651
P577
2002-02-01T00:00:00Z
P5875
P6179
1037796757