Leukotriene B4 enhances the activity of nuclear factor-kappaB pathway through BLT1 and BLT2 receptors in atherosclerosis.
about
BLT2 is a pro-tumorigenic mediator during cancer progression and a therapeutic target for anti-cancer drug developmentLeukotriene B4 as a Potential Therapeutic Target for the Treatment of Metabolic DisordersDiscovery of Leukotriene A4 Hydrolase Inhibitors Using Metabolomics Biased Fragment Crystallography †Polyunsaturated fatty acids and cardiovascular disease: implications for nutrigenetics5-Lipoxygenase inhibitors attenuate TNF-α-induced inflammation in human synovial fibroblastsLow leukotriene B4 receptor 1 leads to ALOX5 downregulation at diagnosis of chronic myeloid leukemia.Leukotriene B4 amplifies NF-κB activation in mouse macrophages by reducing SOCS1 inhibition of MyD88 expression.Retinal upregulation of inflammatory and proangiogenic markers in a model of neonatal diabetic rats fed on a high-fat-diet.The Kaposi's sarcoma-associated herpesvirus (KSHV)-induced 5-lipoxygenase-leukotriene B4 cascade plays key roles in KSHV latency, monocyte recruitment, and lipogenesis.Deficiency of the leukotriene B4 receptor, BLT-1, protects against systemic insulin resistance in diet-induced obesity.Leukotriene B4 receptor-1 mediates intermittent hypoxia-induced atherogenesis.5-(4-Hydroxy-2,3,5-trimethylbenzylidene) thiazolidine-2,4-dione attenuates atherosclerosis possibly by reducing monocyte recruitment to the lesion.LPS Increases 5-LO Expression on Monocytes via an Activation of Akt-Sp1/NF-κB Pathways.EETs Attenuate Ox-LDL-Induced LTB4 Production and Activity by Inhibiting p38 MAPK Phosphorylation and 5-LO/BLT1 Receptor Expression in Rat Pulmonary Arterial Endothelial Cells.Adiponectin-AdipoR1/2-APPL1 signaling axis suppresses human foam cell formation: differential ability of AdipoR1 and AdipoR2 to regulate inflammatory cytokine responses.Platelet microparticles are internalized in neutrophils via the concerted activity of 12-lipoxygenase and secreted phospholipase A2-IIAIntrapulmonary administration of leukotriene B(4) augments neutrophil accumulation and responses in the lung to Klebsiella infection in CXCL1 knockout mice.Leukocytes regulate retinal capillary degeneration in the diabetic mouse via generation of leukotrienes.Elevated levels of leukotriene B4 and thromboxane B2 distinguish chest pain of cardiac and non cardiac origin.Leukotriene B4 levels in human atherosclerotic plaques and abdominal aortic aneurysms.Adipose tissue B2 cells promote insulin resistance through leukotriene LTB4/LTB4R1 signalingA novel positive feedback loop involving FASN/p-ERK1/2/5-LOX/LTB4/FASN sustains high growth of breast cancer cells.Interactions between prostaglandins, leukotrienes and HIV-1: possible implications for the central nervous system.Quantitative metabolic profiling of lipid mediators.The role of leukotrienes in immunopathogenesis of rheumatoid arthritis.Critical Role of LTB4/BLT1 in IL-23-Induced Synovial Inflammation and Osteoclastogenesis via NF-κB.Biochemical and immunological characterization of a novel monoclonal antibody against mouse leukotriene B4 receptor 1.Novel mechanism of regulation of the 5-lipoxygenase/leukotriene B4 pathway by high-density lipoprotein in macrophages.Leukotriene B4 receptor 2 gene polymorphism (rs1950504, Asp196Gly) leads to enhanced cell motility under low-dose ligand stimulation.Integrative transcriptomic analysis reveals key drivers of acute peanut allergic reactions.BLT1 antagonist LSN2792613 reduces infarct size in a mouse model of myocardial ischaemia-reperfusion injury.Too much of a good thing: How modulating LTB4 actions restore host defense in homeostasis or disease.Selective inhibition of leukotriene receptor BLT-2 reduces vascular oxidative stress and improves endothelial function in ApoE-/- mice.In silico epigenetics of metal exposure and subclinical atherosclerosis in middle aged men: pilot results from the Aragon Workers Health Study.Initial Clinical Experience with AZD5718, a Novel Once Daily Oral 5-Lipoxygenase Activating Protein Inhibitor.
P2860
Q24631264-12D0FDC7-3ED3-4981-A62C-6286F172519FQ26779189-0A7D4F9B-83AD-49C8-B3AD-222DA130340FQ27646546-6006A497-93EA-4985-9297-2C0D90E9FC0AQ33647546-F05E281E-CF47-4989-A90A-165A41CB474DQ34208803-CBB76C1D-7860-4368-B69D-75F268ECFDD6Q34463628-843439FD-6059-4821-AFC1-B1997FE57B45Q34519864-0AF03D76-2532-4E42-A23A-9BE2CF701324Q34669369-D645B2DB-0041-4E6A-BE98-3C3489A9E157Q35066362-17985288-1BA5-40C7-A9A4-91EB8BE63E45Q35147692-6FF64339-35E2-4535-B7B9-58D807DB748DQ35212608-988EE686-9F47-4D9D-AE89-E0FB4842F1EAQ35216398-C8121F67-479E-467D-BC52-9C0DDAAF6AA5Q35578620-37585670-B5B0-4D3C-86C4-8F3E6A2EED77Q35649907-4E231226-CCE0-4F25-A4AD-053E1EFBA012Q35785437-A3168266-AF83-49DD-8A09-39222CE12A1AQ35845952-19F1BF97-E02E-496B-935C-673AB260096EQ35851033-765EAB9F-F33A-4007-9263-85B42EF92316Q36476651-4F06C8C4-0F54-40EC-869B-360AE46226E2Q37388158-904DC7AD-18E1-4F83-AB49-0E22C90AF024Q37520764-C9B1DD08-3373-4F0D-AD4F-49313975001BQ37672127-3D56DDB6-6C99-41D6-A860-C3D85E08F302Q37729512-6196C6DB-F1B5-4FAF-B24B-318A93ED8606Q37974980-7F03A1ED-0D60-4C4A-8EDA-51CA0907FD73Q38119472-F3102866-05FD-432F-9B53-14FB7ACA86DCQ38193193-D3B804B8-E7CF-4477-B174-786B45B8C1E2Q39147426-F4A4BA8D-3239-4E10-A452-EDABCFD7FFFFQ41702445-878A7885-6316-4A95-B394-78F6C61C0622Q42374930-5D776098-4023-4D05-88D4-62C38610FF1BQ46255055-D0BD73AE-175B-4C15-B781-2F094C96237DQ47224576-FC958847-4017-4A93-98D2-B682DE42366BQ47355559-53C3D851-7422-4FF9-811B-5D1C427A1776Q50084722-DBD659E4-2339-4E6E-B73C-2CF00EAD54D5Q50529436-B3999A11-3257-49BC-982E-BA8FBA393859Q52568731-F769B007-BBD7-44FD-A302-5F5DFF05BD45Q52667224-FE47E32A-A92B-44A0-BE19-980BD9ADAE9C
P2860
Leukotriene B4 enhances the activity of nuclear factor-kappaB pathway through BLT1 and BLT2 receptors in atherosclerosis.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Leukotriene B4 enhances the ac ...... receptors in atherosclerosis.
@en
Leukotriene B4 enhances the ac ...... receptors in atherosclerosis.
@nl
type
label
Leukotriene B4 enhances the ac ...... receptors in atherosclerosis.
@en
Leukotriene B4 enhances the ac ...... receptors in atherosclerosis.
@nl
prefLabel
Leukotriene B4 enhances the ac ...... receptors in atherosclerosis.
@en
Leukotriene B4 enhances the ac ...... receptors in atherosclerosis.
@nl
P2093
P356
P1476
Leukotriene B4 enhances the ac ...... receptors in atherosclerosis.
@en
P2093
Almudena Gómez-Hernández
Begoña Muñoz-García
Cristina Vidal
Eva Sánchez-Galán
Jesús Egido
José Luis Martín-Ventura
Luis Miguel Blanco-Colio
Luis Ortega
P304
P356
10.1093/CVR/CVN277
P50
P577
2008-10-13T00:00:00Z