N-methyl-D-aspartate receptor subtype mediated bidirectional control of p38 mitogen-activated protein kinase. - Test2 - elhamkhani - TriplyDB

N-methyl-D-aspartate receptor subtype mediated bidirectional control of p38 mitogen-activated protein kinase.

N-methyl-D-aspartate receptor subtype mediated bidirectional control of p38 mitogen-activated protein kinase.

http://www.wikidata.org/entity/Q46557740

about

NMDA and dopamine converge on the NMDA-receptor to induce ERK activation and synaptic depression in mature hippocampus Computational investigation of the changing patterns of subtype specific NMDA receptor activation during physiological glutamatergic neurotransmission Extrasynaptic NMDA receptors couple preferentially to excitotoxicity via calpain-mediated cleavage of STEP Disassembly of shank and homer synaptic clusters is driven by soluble beta-amyloid(1-40) through divergent NMDAR-dependent signalling pathways Enhanced vascular PI3K/Akt-NOX signaling underlies the peripheral NMDAR-mediated pressor response in conscious rats Glucocorticoid rapidly enhances NMDA-evoked neurotoxicity by attenuating the NR2A-containing NMDA receptor-mediated ERK1/2 activation.Spinal mediators that may contribute selectively to antinociceptive tolerance but not other effects of morphine as revealed by deletion of GluR5 Conantokins inhibit NMDAR-dependent calcium influx in developing rat hippocampal neurons in primary culture with resulting effects on CREB phosphorylation.Effect of Conantokin G on NMDA receptor-mediated spontaneous EPSCs in cultured cortical neurons.NR2B-NMDA receptor mediated modulation of the tyrosine phosphatase STEP regulates glutamate induced neuronal cell death NR2B-NMDA receptor-mediated increases in intracellular Ca2+ concentration regulate the tyrosine phosphatase, STEP, and ERK MAP kinase signaling The involvement of neuroinflammation and kynurenine pathway in Parkinson's disease.Switching of N-methyl-D-aspartate (NMDA) receptor-favorite intracellular signal pathways from ERK1/2 protein to p38 mitogen-activated protein kinase leads to developmental changes in NMDA neurotoxicity Compound MQA, a Caffeoylquinic Acid Derivative, Protects Against NMDA-Induced Neurotoxicity and Potential Mechanisms In Vitro.Bi-directional regulation of CaMKIIα phosphorylation at Thr286 by NMDA receptors in cultured cortical neurons Novel crosstalk between ERK MAPK and p38 MAPK leads to homocysteine-NMDA receptor-mediated neuronal cell death.Fyn-mediated phosphorylation of NR2B Tyr-1336 controls calpain-mediated NR2B cleavage in neurons and heterologous systems Phosphoinositide 3-kinase couples NMDA receptors to superoxide release in excitotoxic neuronal death.NR2B-selective conantokin peptide inhibitors of the NMDA receptor display enhanced antinociceptive properties compared to non-selective conantokins.Homocysteine-NMDA receptor-mediated activation of extracellular signal-regulated kinase leads to neuronal cell death.Calpain and the glutamatergic synapse Glutamate-N-methyl-D-aspartate receptor modulation and minocycline for the treatment of patients with schizophrenia: an update.Probing NMDA receptor GluN2A and GluN2B subunit expression and distribution in cortical neurons.Ionotropic NMDA receptor signaling is required for the induction of long-term depression in the mouse hippocampal CA1 region.Developmental localization of NMDA receptors, Src and MAP kinases in mouse brain.Chronic brain inflammation causes a reduction in GluN2A and GluN2B subunits of NMDA receptors and an increase in the phosphorylation of mitogen-activated protein kinases in the hippocampus.Developmental and cell-selective variations in N-methyl-D-aspartate receptor degradation by calpain.Enhanced NMDA receptor tyrosine phosphorylation and increased brain injury following neonatal hypoxia-ischemia in mice with neuronal Fyn overexpression.Ketamine reduces the induced spinal p38 MAPK and pro-inflammatory cytokines in a neuropathic rats.Soluble Aβ oligomers inhibit long-term potentiation through a mechanism involving excessive activation of extrasynaptic NR2B-containing NMDA receptors.Specific targeting of pro-death NMDA receptor signals with differing reliance on the NR2B PDZ ligand.Schizophrenia and depression, two poles of endocannabinoid system deregulation.

P2860

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P2860

N-methyl-D-aspartate receptor subtype mediated bidirectional control of p38 mitogen-activated protein kinase.

http://www.wikidata.org/entity/Q46557740

description

2005 nî lūn-bûn

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年學術文章

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2005年學術文章

@zh-hant

name

N-methyl-D-aspartate receptor ...... ogen-activated protein kinase.

@en

N-methyl-D-aspartate receptor ...... ogen-activated protein kinase.

@nl

type

label

N-methyl-D-aspartate receptor ...... ogen-activated protein kinase.

@en

N-methyl-D-aspartate receptor ...... ogen-activated protein kinase.

@nl

prefLabel

N-methyl-D-aspartate receptor ...... ogen-activated protein kinase.

@en

N-methyl-D-aspartate receptor ...... ogen-activated protein kinase.

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P1433

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P1433

Journal of Biological Chemistry

P1476

N-methyl-D-aspartate receptor ...... ogen-activated protein kinase.

@en

P2093

David R Lynch

http://www.w3.org/2001/XMLSchema#string

Elisa A Waxman

http://www.w3.org/2001/XMLSchema#string

P2860

NMDA receptor function is regulated by the inhibitory scaffolding protein, RACK1

The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist

Functional consequences of NR2 subunit composition in single recombinant N-methyl-D-aspartate receptors

Rescuing impairment of long-term potentiation in fyn-deficient mice by introducing Fyn transgene

Structural Determinants of Phosphoinositide 3-Kinase Inhibition by Wortmannin, LY294002, Quercetin, Myricetin, and Staurosporine

The NMDA receptor is coupled to the ERK pathway by a direct interaction between NR2B and RasGRF1.

Coincidence in dendritic clustering and synaptic targeting of homer proteins and NMDA receptor complex proteins NR2B and PSD95 during development of cultured hippocampal neurons

Activation of PI3-kinase is required for AMPA receptor insertion during LTP of mEPSCs in cultured hippocampal neurons

Changing subunit composition of heteromeric NMDA receptors during development of rat cortex

SynGAP: a synaptic RasGAP that associates with the PSD-95/SAP90 protein family

P304

29322-29333

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scholarly article

P356

10.1074/JBC.M502080200

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P433

32

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P478

280

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P577

2005-06-20T00:00:00Z

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P698

15967799

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