The combined use of ibutilide as an active control with intensive electrocardiographic sampling and signal averaging as a sensitive method to assess the effects of tadalafil on the human QT interval.
about
Update on the evaluation of a new drug for effects on cardiac repolarization in humans: issues in early drug developmentQT/QTc prolongation in placebo-treated subjects: a PhRMA collaborative data analysis.A once-daily dose of tadalafil for erectile dysfunction: compliance and efficacyEffects of atomoxetine on the QT interval in healthy CYP2D6 poor metabolizers.Detecting moxifloxacin-induced QTc prolongation in thorough QT and early clinical phase studies using a highly automated ECG analysis approachTadalafil for the treatment of pulmonary arterial hypertension.Early investigation of QTc liability: the role of multiple ascending dose (MAD) study.Tadalafil: in the treatment of signs and symptoms of benign prostatic hyperplasia with or without erectile dysfunction.Effect of number of replicate electrocardiograms recorded at each time point in a thorough QT study on sample size and study cost.Phosphodiesterase inhibitors, congestive heart failure, and sudden death: time for re-evaluation.Sample size calculations in thorough QT studies.Computerized extraction of electrocardiograms from continuous 12-lead holter recordings reduces measurement variability in a thorough QT study.
P2860
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P2860
The combined use of ibutilide as an active control with intensive electrocardiographic sampling and signal averaging as a sensitive method to assess the effects of tadalafil on the human QT interval.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
The combined use of ibutilide ...... afil on the human QT interval.
@en
The combined use of ibutilide ...... afil on the human QT interval.
@nl
type
label
The combined use of ibutilide ...... afil on the human QT interval.
@en
The combined use of ibutilide ...... afil on the human QT interval.
@nl
prefLabel
The combined use of ibutilide ...... afil on the human QT interval.
@en
The combined use of ibutilide ...... afil on the human QT interval.
@nl
P2093
P1476
The combined use of ibutilide ...... afil on the human QT interval.
@en
P2093
Alex A Dmitrienko
Alun W Bedding
Arash Bakhtyari
Jeffrey T Emmick
Jeremy N Ruskin
Louis R Cantilena
Malcolm I Mitchell
Margaret R Warner
Michael A Turik
Robert A Kloner
P304
P356
10.1016/J.JACC.2005.05.036
P407
P577
2005-08-01T00:00:00Z